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Potatoes… - Bayer CropScience

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New combination of active<br />

substances against potato blight<br />

The new Infinito ® has already established itself in the<br />

market as a highly-effective potato fungicide – within<br />

only a few years of its introduction. The first registrations<br />

were obtained in 2006; in the meantime, Infinito can be<br />

used to control potato late blight (Phytophthora infestans)<br />

in nearly twenty countries. The latest registration was<br />

granted in Japan at the beginning of 2008. The product<br />

will be marketed there under the trade name Reliable ® .<br />

Bad news for potato blight, but good news for Infinito:<br />

in the last few years, the product has been able to demonstrate<br />

its strength in controlling the disease on aboveground<br />

parts and tubers, thereby protecting the entire potato<br />

plant. To achieve this, it draws on the combination of<br />

two highly effective active substances: propamocarb-HCl<br />

und fluopicolide.<br />

Fluopicolide is a new active substance from <strong>Bayer</strong><br />

<strong>CropScience</strong>’s Research Unit. It has a unique mode of action<br />

that leads to a rapid destabilisation of fungal cells.<br />

Products based on this innovative active substance stand<br />

out by virtue of the long-term, consistently high level of<br />

protection they provide to crops, as well as through their<br />

favourable environmental profile.<br />

Fluopicolide’s new mode of action<br />

Fluopicolide acts by disrupting the pathogen’s cell structure.<br />

It inhibits the formation of spectrin-like proteins that<br />

are assumed to play an important role in the stabilisation<br />

of the pathogen’s cells. This unique mode of action is<br />

effective against all of the most critical stages of the<br />

pathogen’s life-cycle. However, fluopicolide’s main target<br />

is the zoospore stage: the spores stop moving within seconds<br />

of coming into contact with the active substance;<br />

then they swell-up, and, eventually, burst. Fluopicolide<br />

also reduces sporulation and suppresses the growth of<br />

fungal mycelia within plant tissues. Moreover, it inhibits<br />

both direct and indirect sporangial germination.<br />

Fluopicolide’s partner in Infinito is the time-tested<br />

active substance propamocarb-HCl, which has been on<br />

the market for 30 years now. Propamocarb-HCl influences<br />

fatty acid synthesis, so it has a completely different mode<br />

of action from fluopicolide. The two active substances<br />

complement each other very well to provide the effective,<br />

long-term protection that Infinito affords. Both possess<br />

systemic and trans-laminar distribution properties. Active<br />

substance taken up by the stem is thus transported to other<br />

parts of the plant, which means that newly-grown plant<br />

tissues can also be protected from infection. ■<br />

Late blight: the thread-like mycelium of the pathogen<br />

Phytophthora infestans has formed a network within<br />

the tissues of the potato plant. The <strong>Bayer</strong> active substance<br />

fluopicolide is particularly active against the zoospores<br />

(contained in the capsules at the ends of the mycelial threads)<br />

that help the late blight pathogen to spread.<br />

1/08 COURIER 21

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