Equipment/Facilities/Services Guide (2.2MB PDF) - Office of Grants ...

Guide to 

Equipment 

Facilities & 

Services at 

Rutgers 

Rutgers University 

Office of Research Alliances 



FYA 

Rutgers’ facilities operate many highly sophisticated 

world-class research technologies that have valuable 

functionalities of interest to researchers in industry 

as well as other academic institutions. 

September 2012

GETTING THE RIGHT PEOPLE IN THE ROOM 



About the Office of Research Alliances 

Director’s Message 

Rutgers’ Office of Research Alliances (ORA) focuses on corporate 

partnerships. Our specialty is getting the right people in the room for high‐impact, highyield 

interactions among faculty and industry. Our team works university‐wide to help 

executives, scientists and others in business find the right people at Rutgers. We do 

that by listening and working with our colleagues across the university to make the 

optimal connections. 

ORA’s main goal is to increase industry engagement with the university. As New Jersey’s 

comprehensive public research university, Rutgers provides broad and integrated resources to external partners and 

ORA helps make those resources more readily available. Formed just two years ago, ORA also promotes intra‐university 

collaborations. Rutgers is a large, dynamic and diverse university, and we pride ourselves on creating new synergies 

within the research enterprise and with our industrial partners. 

→ Thomas Richardson, Director, Office of Research Alliances 

The Imperative 

Influential leaders in American higher education consistently emphasize the need for universities to engage 

more extensively with the commercial sector, given the state of the economy and government budgets. Partnering the 

research enterprise more fully with the corporate sector brings immediate opportunities to faculty and students. It leads 

to the development of innovative education products and transformation of intellectual property into economic benefit 

for the university and stakeholders. Rutgers has a strong foundation to build on, to drive research at the university and 

economic development for the State of New Jersey. 

What We Do 

ORA works with the research community, both inside Rutgers and with the industrial base, to increase 

returns on the research assets at the university. By identifying unmet needs for Rutgers faculty, ORA connects expertise 

for joint programs, and oftentimes introduces faculty who may have never met. An example is a recent internal 

collaboration set up between the RUCDR and the supercomputing capabilities in New Brunswick. 

Further, ORA works directly with companies to generate sponsored research and to recruit members for Rutgers 

corporate‐sponsored centers. 

Office of Research Alliances Guide to Equipment‐Facilities‐Services – September 2012 Page 2




Office of Research Alliances (ORA) 

Guide to Equipment/Facilities/Services from Rutgers University 

INTRODUCTION: 

ORA has created two guides to research equipment/facilities/services that are available to researchers both 

inside and outside of Rutgers. ORA's newly updated guides are intended to: 

Promote research, 

Maximize the use of these resources, 

Provide a means for technology development and opportunities for cooperation, and 

Provide researchers with access to equipment/facilities/services whose purchase and/or maintenance 

expenses might otherwise be cost-prohibitive. 

Many of the items in these guides are a paid service, or their use by trained Rutgers facilities’ affiliates may be 

obtained to provide paid testing/services or as sponsored research. Information regarding fees & contact 

information for Rutgers facilities managers are included for each item. Both guides are available at: 

ora.rutgers.edu/guide. 

If you are interested in any of the equipment/facilities/services please contact: 

the Facility Manager directly, or 

The Rutgers Office of Research Alliances 

Tel: 732-445-3344 or E-mail: frontdoor@rutgers.edu 

This information is not exhaustive, but rather is intended only as a guide - not as an offer of services or access. 

While the information herein was believed to be accurate as of the date of its compilation, all information is 

subject to change (including e.g. prices and availability). Please check with the facilities manager for current 

and complete information, pricing, and any restrictions. This information should only be reproduced with 

permission – to request permission please contact frontdoor@rutgers.edu or 732-445-3344. 





TABLE OF CONTENTS: 

A. Analysis ..................................................................................................................................... Page 5 

1. Flow Cytometry 

2. Microarray reading/scanning 

3. Physical Properties 

i. Hardness 

ii. Rheometer 

4. Spectrometry 

i. Laser Induced Breakdown 

ii. Mass 

iii. Near IR 

iv. NMR 

5. Surface plasmon resonance (SPR) monitoring/measurement 

6. Other 

B. Imaging & Visualization .......................................................................................................... Page 24 

1. Genetics – Imaging Core Facility 

2. Magnetic Resonance Imaging (MRI) 

3. Microscopy 

i. Atomic force 

ii. Confocal 

iii. Fluoresent/Epifluoresent 

iv. STEM 

v. Dissecting 

4. PET/CT 

5. Preclinical Imaging 

6. Ultrasound 

C. Physical Processes ................................................................................................................. Page 47 

1. Drying 

2. Fermentation 

3. Polishing 

4. Machining 

5. Mixing 

D. PCR Tools ................................................................................................................................ Page 63 

E. Cell and DNA Repository ........................................................................................................ Page 64 

F. Microelectronics Research Laboratory .................................................................................. Page 65 

G. Robotics .................................................................................................................................... Page 67 





ANALYSIS: FLOW CYTOMETRY 

C6 Flow Cytometer® Instrument 

DEPARTMENT NAME 

School of Environmental and Biological Science 

INSTRUMENTATION 

The Accuri C6 Flow Cytometer® is equipped with one blue and one red laser, forward and side scatter detectors, and four fluorescence 

detectors with interference filters optimized for the detection of FITC, PE, PerCP-Cy5.5, and APC. Other common fluorochromes that can be 

used with the C6 including GFP, Alexafluors, Texas Red, and Mitotracker Red. The C6’s fully digital data collection system allows complete 

flexibility to display and analyze data post-collection, without any alteration of your original data file. It also allows you to export CFlow files into 

most 3rd party flow cytometry software programs, e.g. FCS Express, FlowJo. Finally, Accuri developed the C6 to use the same reagents 

currently used by leading flow cytometers to allow for ease of transfer of existing protocols developed on different flow cytometers. Since the C6 

fluidics system is non-pressurized, any brand of sample tube that is 12x75 mm or smaller can be used. This includes microfuge tubes and 

tubes made of polypropylene or polystyrene. 

FACILITY MANAGER 

Michael Pierce, Ph.D. 

Nilgun E. Tumer, Ph.D. 

mdpierce@rci.rutgers.edu 

tumer@rci.rutgers.edu 

Phone: 

Phone: 

(732) 932-8165 x127 (732) 932-8165 x215 

Foran Hall 59 Dudley Rd, 


New Brunswick, NJ 08901 New Brunswick, NJ 08901 

http://www.sebs.rutgers.edu/core-facility/ http://www.sebs.rutgers.edu/core-facility/ 

APPLICATION SERVICES 

The C6 is highly versatile and has many applications in cell cycle analysis, immunophenotyping, bacteria analysis, proliferation assays, 

apoptosis, DNA analysis, gene expression, viability, absolute cell counts, intracellular cytokines, membrane potential, yeast and algae 

analysis, and phagocytosis studies. 

IMPORTANT NOTE 

For more information, specifications, and instrument availability, please visit our core facility website, and contact us to schedule an 

appointment. 

COSTS OUTSIDE RUTGERS $30 /hr 

MANUFACTURER WEBSITE 

http://www.accuricytometers.com/products/c6_flow_cytometer/ 

LOCATION 

59 Dudley Rd, New Brunswick, NJ, 08901-8520 





ANALYSIS: MICROARRAY READING/SCANNING 

BioTek Synergy 4 Multi-detection Microplate reader 




BioTek Synergy 4 is a modular microplate reader that offers Monochromator-Based Fluorescence Intensity (M); Filter-Based Top and Bottom 

Fluorescence Intensity (F); Fluorescence Polarization (P); Time-Resolved Fluorescence (T); Luminescence (L); UV-Visible Absorbance (A); and 

Dual Reagent Injection System (D). With its unique Hybrid Technology TM optics, the Synergy 4 covers more applications than any other 

reader on the market. The hybrid fluorescence system comes with two double-grating monochromators, two excitation filters (360/40, 485/20 

nm default), three emission filters (460/40, 528/20, 620/40 nm default) and three mirrors (50%, 400 nm half-size and 510 nm full-size default). 

Temperature control system and shaking are standard. Additional filter sets include: 485/20 EX (EGFP), 516/20 EM (EGFP), 540/35 EX (RFP), 

600/40 EM (RFP), 360/40 EX (DAPI), 460/40 EM (DAPI), 590/20 EX (Texas Red), 645/40 EM (Texas Red) 


appointment. 






Phone: 

Phone: 

(732) 932-8165 x127 (732) 932-8165 x215 

Foran Hall 59 Dudley Rd, New 

Foran Hall 59 Dudley Rd, New 

Brunswick, NJ08901 

Brunswick, NJ08901 

http://www.sebs.rutgers.edu/core-facility http://www.sebs.rutgers.edu/core-facility 


Capable of measuring: 

• fluorescence intensity 

• fluorescence polarization 

• time-resolved fluorescence 

• luminescence 

• UV-visible absorbance 

COSTS OUTSIDE RUTGERS $ 50 /hr 


http://www.biotek.com/products/microplate_detection/synergyh4_hybrid_multimode_m... 

LOCATION 






ANALYSIS: MICROARRY READING/SCANNING 

SGA Robotics: RoToR HDA 




The RoToR HDA is a very small benchtop robot for easy ultra-fast manipulation of high density arrays of yeast or bacteria. The RoToR uses 

plastic replica plating pads and supports liquid pinning to and from 96- and 384-well microtitre plates and agar pinning at densities 96, 384, 768, 

1536, 3072, and 6144. The RoToR HDA is very fast and can process up to 100 plates per hour. It is user-friendly and is very easy to use. It 

supports 96- and 384-well liquid-liquid / liquid-agar / agar-liquid spotting. It allows replication, arraying, mating and breakdown at 96, 384, 768 

and 1536 density. Can dispense to and from solid or liquid media in 96- and 384-well formats with a throughput of up to 100 plates per hour. It 

is compatible with all SBS format plates/trays and shallow multi-well plates 






Phone: 

Phone: 

(732) 932-8165 x127 (732) 932-8165 x215 






Use reagents such as the yeast deletion mutant strain collection for large-scale yeast two-hybrid, synthetic genetic array, phenotypic, 

and chemical-genetic screening analysis. 



appointment. 

COSTS OUTSIDE RUTGERS $80 /hr 


http://www.singerinstruments.com/index.phpoption=com_content&task=view&id=16&It... 

LOCATION 






ANALYSIS: MICROARRAY READING/SCANNING 

Microarray Scanner Axon 4200AL 


Department of Biochemistry and Microbiology 


The Axon Autoloader 4200AL is a scanner for microarrays, tissues and cell arrays, and general fluorescence studies. GenePix Pro 6.0, for 

microarray imaging and analysis, and Acuity 4.0, for data warehousing, advanced statistic analysis and visualization are also available to 

scanner users. 

• Chip format: All 25x75 mm slide arrays: Agilent, Amersham, Illumina, Combimatrix, etc. Up to 36 slides/run 

• Maximum scan area: 22 x 69 mm 

• Resolution: 5, 10 20, 40, 60, 80, 100 um/pixel 

• Scan speed per channel: 5 min (full-size area at 10 um/pixel) 

• Lasers: 532, 635 nm, upgradeable with 488 and 594 nm 

• Laser power settings: 5% to 100% in 1% increments 

• Dynamic range: 16-bit 

• Focus: Adjustable in 1 um steps 


Elisabetta Bini 

bini@aesop.rutgers.edu 

Phone: 

(732) 932-9763 x122 

Dept. of Biochemistry and Microbiology 

76 Lipman Drive 

New Brunswick, NJ 08901 

http://biotech.rutgers.edu /instrumentation/index.html 


For more information, specifications, costs and instrument availability, please visit our core facility website, and contact us to schedule an 

appointment. 


http://www.moleculardevices.com/Products/Instruments/Microarray-Scanners.html 

LOCATION 






ANALYSIS: PHYSICAL PROPERTIES: HARDNESS 

Tablet Tester Model 6D Pharmatron 


Center for Structured Particulate Organic Systems (CSOPS) 


6D the #1 top selling bench top hardness tester worldwide! The Pharmatron Model 6D was first introduced in 1989. After placing more than 

4,000 units in service worldwide the 6D has become the de facto standard in the industry. The Model 6D uses the same strain gauge S beam 

load cell as the current Schleuniger Model 8M and fully automatic Model AutoTest 4. Maintaining the same sensor across the product range 

ensures consistent results throughout the manufacturer's product lifecycle. The Model 6D can be used to measure any shape and form of solid 

dose. Optional quick change fixtures make sample alignment easy and repeatable. An easy to use menu makes product set up a snap. The 6D 

accommodates a plain paper 40 column printer where a comprehensive report is generated automatically after the completion of a test. Using 

the companion user friendly TabStat 2000 software makes data storage and batch evaluation an easy task. You can even export date and 

generate custom reports using MS Excel. 


Eric Erenrich 

Eric.Erenrich@Rutgers.edu 

Phone: 

(732) 445-6711 

Fax: 

(732) 445-6758 Engineering C124B 

http://ercforsops.org/ 


Please contact the facility manager for cost and additional information. 


http://www.pharmatron.ch/ 

LOCATION 

CSOPS Labs, Engineering Wing C, Busch campus Piscataway, NJ 





ANALYSIS: PHYSICAL PROPERTIES: RHEOMETER 

Freeman FT4 Rheometer 




The FT4 Powder Rheometeris a universal powder tester - three instruments in one, combining the Freeman patented blade methodology for 

measuring flow energy with a range of shear cells, wall friction modules and other accessories for measuring bulk properties. The 

methodologies allow measurement of: 

• Flow energy in relation to many variables and all packing states 

• Shear properties of consolidated and unconsolidated powders 

• Bulk properties – precision bulk density, compressibility and permeability 

• Process variables such as moisture, attrition and segregation 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 






http://www.freemantech.co.uk/ 

LOCATION 







Gravitational Displacement Rheometer Custom Made for Rutgers 

By Rothgreaves Inc. 




The GDR measures the cohesive properties of a powder by capturing the changes in the center of mass of a powder bed caused by the 

powder avalanches, as well as recording the dilation of the material due to the initiated flow. The GDR measurement unit consists of an acrylic 

cylinder containing the powder of interest, which rotates on top of a pivot plate. A load cell below the pivot plate records the fluctuations in the 

force signal that correspond to the powder avalanches caused by rotating the drum. Also, the expansion percentage (dilation) of the powder 

bed within the rotating cylinder can be measured with an infrared camera system. With these types of powder measurements it has been 

determined that the volume of the avalanche is directly proportional to the cohesion of the material. In addition, it has been determined that the 

dilated density is directly related to the unconfined density. Combining these concepts and utilizing software powder flow is characterized based 

on a flow index value, where free flowing powders show low flow index values and cohesive powders show high index values. The use of the 

flow index allows for the prediction of powder flow, taking both cohesion and dilated density of the powder into account. 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 



IMPORTANT NOTE: 


LOCATION 







Rheometer Rheoscientific Model # SP 200n 




Rheoscientific rheometer Model#: SP 200n 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 






http://www.rheoinstruments.com/ 

LOCATION 







Shear Rheometer Metropolitan Computing Corporation 




The brain child of Professor Fernando Muzzio, this “controlled shear” apparatus was developed by MCC in close cooperation with Rutgers 

University. It is fully instrumented for measurements of torque and speed. It is designed to analyze the role of shear on the lubrication process 

and on the resulting mechanical properties of drug products 

• Study the effect of shear on lubrication 

• Study the effect of shear on tapped density 

• Study the effect of shear on flow 

• Analyze dilation and flow properties for pure materials and mixtures 

• Study granulation lubrication 

• Study agglomerate breakup 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 






http://www.mcc-online.com/ 

LOCATION 






ANALYSIS: SPECTROMETRY: LASER INDUCED BREAKDOWN 

PharmaLIBS 250 




PharmaLIBS250 is an innovative, patented, laser-based analytical instrument designed for rapid, reliable testing of solid and oral dosage 

pharmaceuticals. Analyses are performed directly on tablets without any sample preparation or extensive sample extraction with solvents. 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 






http://www.pharmalaser.com/ 

LOCATION 






ANALYSIS: SPECTROMETRY: MASS 

SCIEX 4800 MALDI-TOF/TOF Mass Spectrometer 


Center for Advanced Biotechnology and Medicine 


The Applied Biosystems/SCIEX 4800 can perform both MS and MS/MS experiments on a wide variety of compounds including proteins, 

peptides, polymers, and organic compounds. This instrument can be either operated by the facility on behalf of clients or by users themselves. 


Haiyan Zheng, Ph.D. 

Peter Lobel, Ph.D. 

Haiyanz@cabm.rutgers.edu 

Lobel@cabm.rutgers.edu 

Phone: 

Phone: 

(732) 235-5362 (732) 235-5032 

Fax: 

Fax: 

(732) 235-4466 (732) 235-4466 

CABM, Room 112 679 Hoes Lane CABM, Room 204 679 Hoes Lane 

Piscataway, NJ 08854 Piscataway, NJ 08854 

http://cabm-ms.cabm.rutgers.edu/ http://cabm-ms.cabm.rutgers.edu/ 


Molecular weight measurement · Characterization of post-translational modifications (phosphorylation, disulfide bond identification, methylation, 

biotinylation, etc) 

COSTS OUTSIDE RUTGERS 

Users wishing to operate the instrument directly will receive initial training ($270/2 hours) by facility staff and subsequent guidance as needed. 

The cost to use the instrument is $80/hour. For frequent users, our User's Group provides a price discount ($2000 annual fee plus $25/hour) 

and free initial training. Alternatively, samples can be submitted to facility for $45/sample plus any extra costs that may be incurred (purchase of 

special matrix, extra time for methods development, etc) with consent of the user. 


http://www.ABscix.com 

LOCATION 

Location: CABM, Room 112, 679 Hoes lane, Piscataway, NJ 08854 





ANALYSIS: SPECTROMETERY: MASS 

LTQ linear Ion Trap Mass Spectrometer with 

Dionexnano/Analytical HPLC 




The ThermoFisher LTQ operated in nano LC mode is routinely used in tandem mass spectrometry experiments to identify peptides present at 

sub-femtomole levels. In practice, we can identify proteins in gel bands that are present at the lower levels detectable by silver staining (~1 ng). 

The instrument is also operated at higher flow rates for other applications such as H-D exchange. This instrument is generally operated by 

facility staff but some highly experienced users are granted direct access. 






Phone: 

Phone: 

(732) 235-5362 (732) 235-5032 

Fax: 

Fax: 

(732) 235-4466 (732) 235-4466 





• Protein identification 

• Protein structure analysis (H-D exchange, limited proteolysis) 

• Molecular weight measurement 


We strongly advise you to contact the facility director or manager in the early stages of project planning. For more details about facility services, 

prices, and information regarding sample submission, please visit our website and/or contact us via email or phone. 


Cost: $75/1 hour run for nano-LC-MS/MS, including first-pass automated database search. See website for other services. 


http://www.thermofisher.com 

LOCATION 

CABM, Room 112, 679 Hoes lane, Piscataway, NJ 08854 





ANALYSIS: SPECTROMETERY: MASS 

LTQ Orbitrap VELOS EDT Mass Spectrometer with Ultra 

High Pressure Nano HPLC 




The LTQ-Orbitrap-Velos, representing the latest generation of high resolution mass spectrometers, possesses different ion fragmentation 

capabilities including CID, ETD, and HCD. The instrument is particularly useful for applications that require special fragmentation mechanisms, 

high resolution (100,000 ppm), high sensitivity, and/or rapid duty cycle. Such applications include analysis of complex mixtures, posttranslational 

modification studies (e.g., phospho-proteomics, histone code analysis), label-and label-free quantitative proteomics experiments, 

and top-down analysis of intact proteins. 






Phone: 

Phone: 

(732) 235-5362 (732) 235-5032 

Fax: 

Fax: 

(732) 235-4466 (732) 235-4466 





• Protein Identification 

• Quantitative proteomics (iTRAQ, TMT, SILAC labeling and label-free) 

• Molecular weight measurement 

• PTM characterization (Phosphorylation, disulfide bond identification, methylation, biotinylation) 


We strongly advise you to contact the facility director or manager in the early stages of project planning. For more details about facility 

services, prices, and information regarding sample submission, please visit our website and/or contact us through email or phone. 


Cost: $100/60 minute run for nano-LC-MS/MS. For longer runs, we charge $100 for the first 60 min plus $1/each additional min. Price includes 

first-pass automated database search. Note: gradient length is generally based on estimated sample complexity. 


http://www.thermofisher.com 

LOCATION 

CABM, Room 112, 679 Hoes lane, Piscataway, NJ 08854 





ANALYSIS: SPECTROMETRY: NEAR IR 

Near IR Analyzer Thermo Electro Corporation 




Thermo Scientific Antaris II FT-NIR Analyzer sets an industry standard, providing laboratory-based FT-NIR performance in a ready-for-plant 

package. The Antaris II NIR analyzer provides robust and reliable data collection for at-line, online and in-line analysis. 

Analyze any sample type rapidly and accurately—solids, powders, tablets, paste, gel, films, and liquids 

• ValPro* Instrument Qualification package contains all the tools necessary to make regulatory compliance easy—DQ, IQ, OQ, and PQ 

• Industry-leading method transfer performance 

• Reproducible regardless of configuration, maintenance, user, or environment 

• Rugged design ready for fast, precise and accurate measurements in the lab or in the plant 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 






http://www.thermoscientific.com/ 

LOCATION 






ANALYSIS: SPECTROMETRY: NMR 

Department of Chemistry and Chemical Biology 

NMR Facility 




The NMR (Nuclear Magnetic Resonance) facility contains five Varian (currently Agilent, http://www.chem.agilent.com/) and two Bruker 

(http://www.bruker-biospin.com/) NMR spectrometers for solution state samples. The Varian VNMRS 300 MHz NMR is equipped with a 7.0 T 

Oxford magnet, two RF channels, and an AutoSwitchable probe (4 nucleus mode; 1 H, 19 F, 31 P, 13 C). A Switchable probe (using a broad band X- 

channel) is available. 

• The Varian VNMRS 300 MHz NMR is equipped with a 7.0 T Oxford magnet, two RF channels, and an AutoSwitchable probe (4 nucleus 

mode; 1 H, 19 F, 31 P, 13 C). A Switchable probe (using a broad band X-channel) is available. 

• The Varian VNMRS 400 MHz NMR is equipped with a 9.4 T Oxford magnet, two RF channels, and an AutoX Dual Broadband probe 

with ProTune*. 

• The Varian VNMRS 500 MHz NMR is equipped with an 11.7 T Magnex magnet, two RF channels, and an AutoX Dual Broadband probe 

with ProTune*. 

• The Varian VNMRS 600 MHz NMR is equipped with a 14.1 T Oxford magnet, four RF channels, and a HCN warm probe (a triple 

resonance probe for 1 H, 13 C, and 15 N). A HCN cold probe is available. 

• The Varian VNMRS 800 MHz NMR is equipped with an 18.8 T Magnex magnet, four RF channels, and a HCN warm probe. A HCN cold 

probe is available. 

• The Bruker Avance III 600 MHz NMR is equipped with a 14.1 T Bruker magnet, four RF channels, and a TXI room-temperature probe (a 

triple resonance probe for 1 H, 13 C, and 15 N) with ATM*. 

• The Bruker Avance III 700 MHz NMR is equipped with a 16.4 T Bruker magnet, four RF channels, and a TCI CryoProbe with ATM*. A 

TXI room-temperature probe with ATM is available. 

• ProTune and ATM are automated probe tuning and matching devices. 


Dr. Nagarajan Murali 

Dr. Seho Kim 

nmurali@rci.rutgers.edu 

seho@rci.rutgers.edu 

Phone: 

Phone: 

(732) 445-6592 (732) 445-1288 

Wright-Rieman Labs 610 Taylor Road 

Wright-Rieman Labs 610 Taylor Road 

Piscataway, New Jersey 08854 Piscataway, New Jersey 08854 

http://rutchem.rutgers.edu/nmr_facility 

http://rutchem.rutgers.edu/nmr_facility 


The NMR facility is divided into two operational groups. Varian VNMRS 300, 400, and 500 MHz NMR’s are used for research on small organic 

and inorganic chemicals. Varian VNMRS 600 and 800 MHz and Bruker Avance III 600 and 700 MHz NMR’s are used for biomolecular NMR for 

structure and dynamics study of biological macromolecules. Facilitymanagers provide user training, applications development, and NMR 

related lectures. 

IMPORTANT NOTE Instrument scheduling: Use our web-based NMR scheduling application: 

(https://ccbapps.rutgers.edu/ccb_nmr_schedule/ login.aspx) within our building to sign up for NMR time. You will need a University “NetID” to 

gain access to the scheduler. External users can apply for a guest NetID by following the instructions noted on the Computing Services web 

pages (https://netid.rutgers.edu/). Once you obtain your NetID, contact a member of the NMR facility staff. 





ANALYSIS: SPECTROMETRY: NMR 


NMR Facility (continued) 

New User Training: 

All new users must complete the New User NMR Training course to use NMR instruments. Please contact a member of the facility staff for the 

training schedule. After completion of the training, new users must fill out the New User Access form to obtain an NMR UserID. External users - 

not collaborating with a PI in the Department of Chemistry and Chemical Biology - must pay a one-time training fee of $100.00 per person. 

Billing Rates: 

$45.00/hr for self-service $160.00/hrfor assisted data acquisition All users acquire NMR data for themselves. Please contact a member of the 

facility staff for assisted data acquisition. The billing rates are for external users. Rutgers internal billing rates are subject to change. Contact the 

Facility Manager for current rates. 

LOCATION 

The NMR facility is located at Wright-Rieman Labs, 610 Taylor Road, Piscataway, NJ 08854-8066. The 800 MHz NMR is located at Technology 

Center of NJ, 671 Route 1 South, North Brunswick, NJ 08902. 





ANALYSIS: SPR MONITORING/MEASUREMENT 

Biacore TM 3000 




Biacore 3000 offers label-free detection of biomolecular binding and is an ideal system for all research laboratories, providing high quality data 

on the kinetic and affinity parameters for a given biomolecular interaction. Biacore 3000 is an invaluable tool for exploring protein function and 

is used by proteomics groups, therapeutic cancer research, neuroscience, immunology and infectious disease laboratories in academic, 

pharmaceutical and biotech facilities around the world. The minimal working range of Biacore 3000 is 10 RU, maximum sample capacity is 2 x 

96 + 8 reagent vials and injection volume between 5-750 μl. 






Phone: 

Phone: 

(732) 932-8165 x127 (732) 932-8165 x215 






• Quantitative kinetic analysis (rate constants) 

• Quantitative determination of affinity constants 

• Concentration determination 

• Determination of binding specificity 


Surface Plasmon Resonance (SPR) is used to monitor macromolecular interactions in real time. The Biacore systems (Biacore 3000 and 

Biacore T200) use SPR technology for measuring the interactions of macromolecules with each other, and with small molecules. One of the 

molecules (ligand) is immobilized on carboxymethylated dextran over a gold surface while the second partner (analyte) flows over the 

immobilized ligand surface. Interaction is detected via SPR, in real time, with high sensitivity, without the use of radioactivity. The bound analyte 

can be stripped from the immobilized ligand without affecting its activity to allow many cycles of binding and regeneration on the same 

immobilized surface. These instruments excel over most other methods of affinity measurements in that they are able to measure on-rates (ka 

in the range of 10 3 - 5x10 7 M -1 s -1 ) and off-rates (kd of 10 -5 - 1 s -1 ). For more information, specifications, and instrument availability, please visit our 

core facility website, and contact us to schedule an appointment. 

COSTS OUTSIDE RUTGERS $1,500 /day 

* The Biacore 3000 is a shared instrument between the School of Environmental and Biological Sciences and the School of Pharmacy on the 

Busch Campus of Rutgers University. 


http://www.biacore.com/lifesciences/products/systems_overview/ 

LOCATION 






ANALYSIS: SPR MONITORING/MEASUREMENT 

Biacore T200 




Biacore T200 is a versatile, label-free system that uses SPR for detailed studies of biomolecular interactions. It has exceptional sensitivity, 

which enables interaction analysis with greater precision and confidence. It can be used to: 

• Obtain high quality kinetics from the fastest on-rates to the slowest off-rate 

• Analyze interactions involving the smallest low molecular weight compounds 

• Can process up to 384 samples in unattended runs 

• Has flexible software with high-level user guidance for fast assay development, analysis and evaluation 

• Has guided workflows with built-in data quality assessments and tools 






Phone: 

Phone: 

(732) 932-8165 x127 (732) 932-8165 x215 






• Comprehensive characterization of biomolecular interactions - including kinetics, affinity, specificity and concentration 

• Detailed analysis of structure-function relationships 

• Increased understanding of molecular pathways and biological mechanisms 

• Confident identification/selection of potential drug targets, diagnostic markers and research tools 


Surface Plasmon Resonance (SPR) is used to monitor macromolecular interactions in real time. The Biacore systems (Biacore 3000 and 

Biacore T200) use SPR technology for measuring the interactions of macromolecules with each other, and with small molecules. One of the 

molecules (ligand) is immobilized on carboxymethylated dextran over a gold surface while the second partner (analyte) flows over the 

immobilized ligand surface. Interaction is detected via SPR, in real time, with high sensitivity, without the use of radioactivity. The bound 

analyte can be stripped from the immobilized ligand without affecting its activity to allow many cycles of binding and regeneration on the same 

immobilized surface. These instruments excel over most other methods of affinity measurements in that they are able to measure on-rates (ka 

in the range of 10 3 - 5x10 7 M -1 s -1 ) and off-rates (kd of 10 -5 - 1 s -1 ). 


appointment. 


http://www.biacore.com/lifesciences/products/systems_overview/ 





ANALYSIS: OTHER 

PharmaLIBS 250 




PharmaLIBS250 is an innovative, patented, laser-based analytical instrument designed for rapid, reliable testing of solid and oral dosage 

pharmaceuticals. Analyses are performed directly on tablets without any sample preparation or extensive sample extraction with solvents. 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 






http://www.pharmalaser.com/ 

LOCATION 






IMAGING & VISUALIZATION: 

Carestream In-Vivo MS FX PRO 


Rutgers University Molecular Imaging Center - http://imaging.rutgers.edu/ 


The Carestream In Vivo MS FX PRO® system is designed for researchers who need to image and monitor pathologies within small animals 

using optical probes and radioactive probes in 2D. Multiple mice or rats can be imaged simultaneously. The system can image small animal 

models using any combination of fluorescence, luminescence, radio-isotopic and radiographic imaging modalities. The system comes with 

a high resolution X-ray system capable of generating high resolution X-ray for co-registering optical signals to anatomical landmarks as well as 

tracking and quantifying changes in bone and soft tissue. This system also provides researchers an advanced methodology for the removal of 

non-specific autofluorescence excitation based spectral deconvolution. This software can also be utilized to image multiple fluorescent probes 

simultaneously. These optical imaging modalities are most often used for tumor and stem cell tracking, imaging enzyme activity with 

activatable probes, inflammation imaging, and cell death imaging. Researchers developing novel optical probes including peptides, 

antibodies and nanoparticles can also utilize this instrument to rapidly validate the targeting and specificity of their probes. For researchers 

designing translatable probes the MS FX PRO can serve as a pre- screening tool prior to imaging on the Albira PET/CT using the radio-isotopic 

screen or by leveraging multi functional fluorescence and radio-isotopic probes and biomarkers. 


wendy.sun@rutgers.edu 

Phone: 

(848) 445-1563 

LOCATION 

41 Gordon Road, Piscataway New Jersey 






IVIS 100 




The IVIS 100 is a sensitive and large field of view imaging system. The IVIS 100 offers an adjustable field of view of 10 – 25 cm, allowing 5 mice or 2 large rats 

to be imaged. The system features a 25 mm (1.0 inch) square back‐thinned, back‐illuminated CCD, which is cooled to ‐90 °C via a closed system to minimize 

electronic background and maximize sensitivity. An extremely light tight, low background imaging chamber allows the IVIS 100 to be used in standard lab 

lighting environments. 

The system includes animal handling features such as a heated sample shelf, gas anesthesia connections, and an optional full anesthesia system. 

The IVIS 100 is highly automated with all hardware motor movement, imaging parameters, and image analysis controlled via Living Image software. 

Specialized Living Image software from Caliper controls the imaging process as well as image acquisition and analysis. 



Phone: 

(848) 445-1563 

LOCATION 41 Gordon Road, Piscataway New Jersey 






Genetics - Imaging Core Facilities 


School of Arts and Sciences, Department of Genetics 


The imaging core facilities for the Human Genetics Institute of New Jersey consist of four instruments for shared use by the genetics 

department faculty. The primary instrument is a Zeiss Laser Scanning confocal microscope system with 3-Dimensional image reconstruction 

software, multispectral fluorescence deconvolution and FRAP capabilities. There is also a Zeiss/P.A.L.M. Laser Dissecting Microscope, a Zeiss 

epifluorescence microscope system equipped with a high-sensitivity CCD camera for long-term live cell imaging. The fourth system is a truecolor 

bright-field/ epifluorescence Nikon microscope system for histology. 


Management and oversight of the Human Genetics Institute of New Jersey Imaging Facility is performed by Dr. Serrano 

(Serrano@biology.rutgers.edu) with technical support from Dr. Kane-Goldsmith (noriko@rci.rutgers.edu). 

COSTS - Go to http://genetics.rutgers.edu/content/files/Instruments_ApplicationForm_Fees.pdf 

Instrument HGI members Rutgers External 

Zeiss LSM 510 META 

Assisted/Training 

Unassisted * 

$ 50/h $100/h $150/h 

Zeiss PALM, Microbeam $ 30/h $ 60/h $120/h 

Zeiss AxioObserver Z1 $ 20/h $ 35/h _ 

Zeiss AxioVert 200M 

and/or 

Nikon Eclipse E800 

$500/yr $1,000/yr _ 

*Unassisted use 

requires certification 

from facility 

administrator 





IMAGING & VISUALIZATION: MRI 

Siemens 3T MRI 


Rutgers University Brain Imaging Center 


Siemens 3T MRI RUBIC uses a 3T Siemens TRIO for scanning both humans and animals. 

• Bore inner tunnel diameter = 60 cm 

• Max participant weight = 200 kg (440 lbs) 

• Maximum FOV = 50 cm 

• 32 channel head coil 

RAVANA computing cluster Ravana is 28 node cluster used for RUMBA analyses and has: 

• 25 dual AMD Opteron nodes 1.4GHz (10 nodes - Opteron 240) 

o MainNode: ravana (8GB RAM) 

o node11-node25 (6GB RAM) 2 dual-core Opteron nodes 2.2GHz 

o Opteron 275 

o node26,node27 (12GB RAM) 

• 1 dual CPU Itanium (ia64) [itanix] 

• 1 dual-core Opteron 270, 2GB RAM [raider] OS 

All nodes are running amd 64 (Debian GNU/Linux). 

Eyetracking 

An Eyelink-1000 is available for the collection of eye movement data while scanning. 

• non-ferromagnetic optimized design 

• up to 2000 Hz sampling rate 

• down to 0.01Âº RMS spatial resolution 

• real-time eye position access of 1.4 msec (SD < 0.4 msec) @ 2000 Hz 

• supports Camera-to-eye distances of 60 - 150 cm 

Physiological Recording 

A BIOPAC MP150 system is available for recording GSR and ECG. Other modules can be added as needed. Pulse and respiration can also be 

recorded using Siemens TRIO physiological measurement units. 

Stimulus Presentation 

Both Windows 7 and Ubuntu linux computers are available for use. Pre-loaded stimulus presentation software includes E-Prime (Windows) as 

well as PyEPL, PsychoPy, and OpenSesame (Linux). 

Response Acquisition 

A number of fiber optic response options are available including multi-button response pads and trackballs. 


M. Reza Tehrani 

mr.tehrani@rutgers.edu 

Phone: 

(973) 353-3313 

http://rubic.rutgers.edu/ 






Siemens 3T MRI (continued) 


Scanning 

RUBIC offers a state-of-the-art imaging facility for both MRI and fMRI scanning and is available to researchers studying either humans or 

animals. 

Consultation 

Fee-based consulting services for experimental design, scan operation, and data analysis are available on request. 

LOCATION 

197 University Avenue, Newark, NJ, 07102-1814 






M2 Compact High-Performance MRI (1 T) 




Aspect's M2 platform and suite of products enables users to harness the power and insights of MRI but without the cost, complexity and 

technical burden of traditional MRI systems. With Aspect’s integrated and simple-to-use platform, researchers can derive deep insights into 

their biological questions quickly, easily and cost-effectively with the push of a button. The system has no fringe magnetic field, therefore the 

M2 can be placed anywhere in a working lab including at a scientist’s benchtop. 

The M2 platform is used by leading institutions for a broad range of in vivo, ex vivo and in vitro applications including high-resolution 3D 

anatomical, molecular, functional and multi-modality imaging. The Aspect high-performance MRI system is used to quantify the expression of 

disease, to monitor disease progression and to assess therapeutic efficacy and response. 



Phone: 

(848) 445-1563 

LOCATION 






IMAGING & VISUALIZATION: MICROSCOPY 

Lasentec PVM In-Process Real-Time Imaging Microscope 




Particle Vision and Measurement (PVM®) provides the ability to see particles and droplets as they naturally exist in a crystallizer, vessel or 

pipeline. With rapid capture, saving, and analysis of microscope-quality images at full process concentration, the PVM® facilitates detailed 

understanding of complex particle systems faster than any other method. 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 






http://www.mt.com/alasentec 

LOCATION 






IMAGING & VISUALIZATION: MICROSCOPY 

Microscopy Sample Preparation 


Institute for Advanced Materials, Devices and Nanotechnology (IAMDN) 


We have everything you need when it comes to preparing your SEM/TEM samples. Whether 

you need to section slices of your material for making cross-section TEM samples, to polish 

specimens to the finest degree, or sputte away material with an ion beam for the thinnest 

samples possible, we can help you produce a high quality sample for study. 

Interactive Sample Prep Guide 

Sample Prep Workshops have been offered in the past by Daniele Laub from the Swiss 

Federal Institute of Technology. Daniele Laub is the co-author of the book entitled "Sample 

Preparation Guide for Transmission Electron Microscopy", (2010, Springer) and of an 

interactive website on TEM sample preparation website. 

Overview of Sample Prep Methods 

The Tripod Method to Prepare Cross Sectional TEM Speciman 

The Model 170 Ultrasonic Disk Cutter rapidly cuts transmission electron microscopy (TEM) 

specimens from hard, brittle materials without mechanical or thermal damage. It directly 

produces disk specimens from materials as thin as 10 microns, cylindrical rods up to 10mm 

long from bulk samples, or rectangular wafers that are subsequently used in the preparation of 

cross-section TEM (XTEM) specimens. The MultiPrep System enables precise semiautomatic 

sample preparation of a wide range of materials for microscopic (optical, SEM, 

TEM, AFM, etc.) evaluation. Capabilities include parallel polishing, precise angle polishing, 

site-specific polishing or any combination thereof. It provides reproducible sample results by 

eliminating inconsistencies between users, regardless of their skill. The MultiPrep eliminates 

the need for hand-held polishing jigs, and ensures that only the sample makes contact with the 

abrasive. It maintains geometric orientation of the sample relative to the abrasive plane during 

polishing, allowing quantification of material removal; rate of polish can be monitored, and total 

amount removed can be preset. The Model 650 Low Speed Diamond Wheel Saw is a 

compact, multipurpose, precision saw designed to cut a wide variety of materials with minimal 

subsurface damage. It's low speed makes it possible to cut fragile materials that would 

otherwise fracture and soft materials that would load the diamond wheel on a higher speed 

saw. A variety of sample holders provides a means for mounting any shape sample while 

goniometer adaptability simplifies cutting oriented crystals. Ion milling is used on physical 

science specimens to reduce their thickness to electron transparency. Inert gas, typically 

argon, is ionized and then accelerated toward the specimen surface. By means of momentum 

transfer, the impinging ions sputter material from the specimen at a controlled rate. Liquid 

nitrogen cooling of the specimen stage is highly effective in eliminating heat-induced artifacts. 


Prof. Frederic Cosandey 

LOCATION 

McLaren Center for Ceramic, Research Building, CCR 128 





IMAGING & VISUALIZTION: MICROSCOPY: ATOMIC FORCE 

Digital Instruments Bioscope Atomic Force Microscope 


Department of Biomedical Engineering, Facility of Confocal Imaging 


EMSL's Digital Instruments BioScope Atomic Force Microscope (AFM) combines optical and AFM techniques used to examine heterophase 

processes on mineral surfaces and to image biological systems, such as bacterial colonies, on minerals and other substrates. The BioScope 

AFM allows samples to be examined in fluids or air with little or no sample preparation. Its optics provide an effective magnification range of 25 

to 10,000,000 times and can be used simultaneously with bright-field, fluorescence, and confocal techniques. The microscope supports all 

major AFM-imaging techniques and modes, including contact and intermittent contact (TappingMode) atomic force, lateral force, force 

modulation, phase, lift, etc. The system's NanoScope IV controller enables high-speed data capture of high-pixel-density images (up to 4096 

data points per scan line) that makes possible characterization of surface interactions at timescales previously inaccessible to the scanning 

probe microscope. The controller enables simultaneous acquisition through up to four independent data acquisition channels. A full range of 

data acquisition and analysis algorithms is included in the upgraded control software. 

• Digital Instruments Bioscope AFM with Contact and Tapping Mode 

• Vibration-free compressed air table 

• Zeiss Axiovert Inverted Light Microscope 

• Dual monitor setup 

• Internal Zip drive and Ethernet combo board for image storage and exportation 

*Info: http://www.emsl.pnl.gov/capabilities/viewInstrument.jspid=1039 

Surface view of polyethylene glycol variant copolymer with human plasma fibronectin, done in Tapping Mode. (Courtesy: R. Sharma & Dr. P. 

Moghe, 2003) 


Dr. Prabhas Moghe 

Joseph Kim 

moghe@rutgers.edu 

joekim@rutgers.edu 

Phone: 

Phone: 

(732) 445-4500 x6315 (732) 445-4500 x6376 or x6013 

599 Taylor Road. Piscataway, NJ 08854 599 Taylor Road. Piscataway, NJ 08854 

http://www.confocal.rutgers.edu 




appointment. 


http://www.bruker-axs.com/atomicforcemicroscopy.html 

LOCATION 599 Taylor Road, Piscataway, NJ 08854 





IMAGING & VISUALIZATION: MICROSCOPY: CONFOCAL 

Leica TCS SP2 Confocal Microscopy Workstation 




• Argon-Krypton Laser for Light Emission at 488nm (blue), 568nm (green), and 647nm (red) · 

• Fluorescence Emission Filters: Long Pass (LP) 515, 520, and 590nm; Band Pass (BP) 575-640, 590-610, and 670-810nm · 

• Photomultiplier Tube (PMT) detectors for imaging three channels (any combination of two fluorescent modes, and a reflected or 

transmitted mode) · 

• Objectives for 10x, 20x, 40x, 63x (dry and glycerin immersion) and 100x (oil immersion) · 

• Differential Interference Contrast (DIC) optics · 

• Motorized specimen stage in x, y, and z-directions with a minimum stepsize of 50nm · 

• Incubator-stage apparatus providing atmospheric and temperature control · 

• Vibration-free compressed air table · 

• Stage adaptability to diverse specimen carriers, including slides, Petri-dishes, and Mat-Tek chambers · 

• Two IBM compatible computers equipped with Image Analysis software for digital image acquisition, image processing, and 

measurement · 

• Image Pro Plus Image Analysis Software · 

• External SCSI Iomega Jaz and Zip drives and ethernet combo board f 

Presence of voids on the external surface of a clinically approved biomaterial scaffold. Surface contour details can also be visualized 

surrounding the voids. (Courtesy: E.J Semler, 1997 



Joseph Kim 



Phone: 

Phone: 

(732) 445-4500 x6315 (732) 445-4500 x6376 or x6013 






appointment. 

http://www.confocal.rutgers.edu/fees.html 


http://www.leica-microsystems.com/products/confocal-microscopes/details/product/... 

LOCATION 

599 Taylor Road, Piscataway, NJ 08854 






Zeiss LSM 710 Confocal Microscope 




Laser lines 

The LSM 710 is capable of 34 spectral detection channels using six laser lines - 405, 458, 488, 514, 561 & 633 nm, plus an additional 594 

nm HeNe laser (includes replacement main beam splitter wheel equipped for 458, 488, 514, 561, 594 & 633 nm laser lines). The 561 and 

594 lasers are needed to visualize mCherry, Texas Red, and other red fluorophores including Alexa 568, Alexa 594. 

Fluorescence Equipment 

The LSM 710 uses a six position turret that houses cubes holding a DAPI fluorescence filter, a Cy3 fluorescence filter and a GFP fluorescence filter. 

Transmitted light equipment 

The transmitted light source uses a halogen bulb for transmitted light source and a mirror to switch between transmitted light source and 

transmitted PMT (detector). 

HBO Illuminator 

The fluorescence light source uses a mercury bulb and power supply along with a touch pad for microscope control with docking station. 

Manual Stage 

The stage for microscope has specimen holders for slides and petri dishes allowing for imaging of fixed and live cell samples. 

Lens Objectives 

The LSM 710 has 10X, 20X, 40X oil, 63X water and 100X oil objectives and Nomarski optics. 

Environmental Control System 

An incubator chamber encloses the microscope allowing for temperature control during image acquisition. A heated insert for the stage holds 

petri dishes and a cover for this insert delivers CO2. The Environmental Control Chamber can be used for containment of mammalian cells and 

C.elegans allowing for motility studies. For temperature sensitive experiments the microscope stage can be cooled allowing for a working 

temperature range of 4°C to 45°C. 

Computer driven X-Y stage 

The computer driven X-Y stage allows imaging of multiple fields over time for any given live specimen. It is ideal for projects that collect multiple 

images over a period of time intervals or require imaging of multiple animals (C. elegans, Drosophila, mammalian cells). This stage allows for 

imaging to take place in parallel, rather than serially, facilitating collection of more data over the length of the experiment. 

FRET/FRAP software package 

The LSM 710 is fitted with quantitative FRET/FRAP (Fluorescence Resonance Energy Transfer/ Fluorescence Recovery after Photobleaching) 

software package allowing for acquisition and analysis of sensitized emission, acceptor photobleaching and Emission fingerprinting based 

FRET and FRAP fitting parameters to establish rate constants for recovery. 

Image VisArt plus program module 

Permits innovative 3D and 4D renderings of the data. Up to three clipping planes allow different rendering modes within the same sample. 






Phone: 

Phone: 

(732) 932-8165 x127 (732) 932-8165 x215 










Zeiss LSM 710 Confocal Microscope (continued) 



appointment. 

COSTS 

Non- Rutgers users: 

Fees: $ 100 /hr 

Assisted use fee : $ 200 /hr 

Annual use: 

$ 6,000 / 1000 hr 

$ 4,000 / 100 hr 

$ 2,000 / 40 hrs 


http://www.zeiss.de/c12567be0045acf1/Contents-Frame/abe2e11db0ad4e88c12567c1005b... 

LOCATION 







Zeiss LSM 510 Confocal Microscope 





department faculty. The primary instrument is a Zeiss Laser Scanning confocal microscope system with 3-Dimensional image reconstruction 

software, multispectral fluorescence deconvolution and FRAP capabilities. The Zeiss LSM510 META is a laser scanning system built on an 

Axiovert 200M microscope stand equipped with a high-precision motorized XY stage (50 nm Z-step size), with “Mark & Find” functions. The 

system has four Zeiss objective lenses, EC Plan-Neofluar 10x/0.3 NA, Plan-Apochromat 20x/0.8 NA, C. Apochromat 63x/1.2 NA water 

(Nomarski DIC) and Plan-Apochromat 100x/1.46 NA oil to accommodate from large tissue imaging to high resolution 3-D rendering. The 

system has three single channel PMT detectors and META, a polychromatic 32-channel detector for spectral imaging/emission fingerprinting. 

META detector can also be used as a PMT detector with freely definable emission ranges. The system is equipped with 4 lasers from visible to 

far red excitation range (switching time < 5 μs): Argon (458, 477, 488 and 514nm lines), HeNe543nm, HeNe633 nm and a 405nm blue diode 

laser. 






Zeiss LSM 510 META 

Assisted/Training 

Unassisted * 

$ 50/h $100/h $150/h 





IMAGING & VISUALIZATION: MICROSCOPY: 

FLUORESCENT/EPIFLUORESCENT 

ZEISS/ P.A.L.M. Laser Dissecting Microscope 





department faculty including a Zeiss/P.A.L.M. Laser Dissecting Microscope. The Zeiss P.A.L.M., the Microbeam. Is an inverted fluorescent 

microscope Axiovert 200M equipped with laser micro-dissecting module for contact-free and contamination-free specimen capture from archival 

material to living cells. The system has four objective lenses (Fluar 5x/0.25 NA, Fluar 10x/0.50 NA, Fluar 20x/0.75/NA, and Fluar 100x/1.3 NA) 

and two illumination sources, bright-field and epifluorescence for specimen viewing. For more information see: 

http://www.zeiss.com/C1256D18002CC306/0/1042746EDBB1F8BEC125727D003C07D5/$file/49-0006_e.pdf 













Nikon Eclipse TE2000-S Epifluorescent Microscope 




• X-Cite® 120Q system uses a 120-watt lamp to deliver rich spectral excitation with a uniformly illuminated field of view. The optional 

adjustable iris allows the user to set the level of illumination. 

• 3 fluorescence filter blocks: Ultraviolet Excitation (UV-2E/C) Ex 340-380 and Em 435-485, Blue Excitation (UV-2E/C) Ex 465-495 and 

Em 515-555, Yellow Excitation (Y-2E/C-TR) Ex 540-580 and Em 600-660 

• Objectives for 4x, 10x, 20x, 40x, and 100x magnification 

• Differential Interference Contrast (DIC) optics 

• Motorized specimen stage in x and y directions 

• Stage adaptability to diverse specimen carriers including well-plates, slides, Petri-dishes, and Mat-Tek chambers 

• Dage Excel Digital Firewire Camera 

• Dell computer equipped with Image Analysis software for digital image acquisition, image processing, and measurement 

• Image Pro Plus Image Analysis Software 

• Attached to Cytoviva Microscope System 



Joseph Kim 



Phone: 

Phone: 

(732) 445-4500 x6315 (732) 445-4500 x6376 or x6013 





Imaging of fixed biological samples 



appointment. 

*In addition to our microscopes, the Department of Biomedical Engineering, Facility of Confocal Imagingalso offer a tissue culture facility 

conveniently located in the same suite as the Confocal and Atomic Force Microscopes: 

• Labconco Purifier Class II Safety Cabinet 

• 2 Forma-Scientific Water Jacketed Incubators 


http://www.confocal.rutgers.edu/fees.html 


http://www.nikon-instruments.jp/eng/page/products/te2000.aspx 

LOCATION 

599 Taylor Road, Piscataway, NJ 08854 







Zeiss Observer Z1 



INSTRUMENTATION The imaging core facilities for the Human Genetics Institute of New Jersey consist of four instruments for shared use by 

the genetics department faculty. This includes a Zeiss epifluorescence microscope system equipped with a high-sensitivity CCD camera for 

long-term live cell imaging. More specifically, the Zeiss Observer Z1 is an advanced inverted fluorescence microscope with motorized stage 

and two AxioCam cameras (MRc for color and MRm for fluorescence). A new illumination system (Lumen 200; PRIOR) is a long lasting 200 

watt metal arc lamp known for its extended transmission in UV and IR. There are four fluorescence filter sets, DAPI, GFP, Texas Red and Cy5 

for multi-fluorescence imaging. Selection of objective lenses is suitable for live cell imaging through a culture dish and they include EC-Plan 

Neofluar 10x, LD-Plan Neofluar 20x and LD-Plan Neofluar 40x long working distance/phase contrast lenses. Axiovision ver. 4.8 is versatile and 

programmable acquisition software and the applications include automatic multi-fluorescence, time-lapse and tile imaging (Mosaix). 






Zeiss AxioObserver Z1 $ 20/h $ 35/h _ 







ZEISS AXIOVERT 200M 





department faculty. This includes the Zeiss Axiovert 200M. An inverted fluorescence microscope with motorized Z-axis acquisition and a filter 

wheel with DAPI, GFP, Texas Red and bright field. Objective lenses include Plan-Noefluar 10x/0.3 NA, EC Plan-Neofluar 20x/0.5, LD Achro- 

Plan 40x/0.6, and Plan-Apochromat 63x /1.4 oil. The system is equipped with sensitive Retiga-SRV (Q-Imaging) CCD camera for high 

resolution/low-light detection and with Slidebook, the advanced acquisition software (3i, Intelligent Imaging Innovations). Good for fixed cell 

specimens and chromosome/karyo-type imaging. 






Zeiss AxioVert 200M $500/yr $1,000/yr _ 







NIKON ECLIPSE E800 





department faculty. The Nikon Eclipse E800 is an upright fluorescence/bright-field equipped with “Micro Color”, liquid crystal tunable RGB filter 

(CRI Inc.) for true-color imaging. Objective lenses include Plan 2x/0.06 NA, Plan-Fluor 4x/0.13 NA, Plan-Apo 10x/0.45 NA, Plan-Apo 20x/0.75 

NA, Plan-Fluor 40x/0.75 NA, Plan-Apo 60x/1.4 NA oil and Plan-Fluor100x /1.3 NA oil. The system is equipped with a Retiga1300 CCD camera 

(Q-Imaging) and uses QCapture as basic acquisition software. Good for histology-stained specimens. 






Nikon Eclipse E800 $500/yr $1,000/yr _ 





IMAGING & VISUALIZATION: MICROSCOPY: STEM 

JEOL 2010F STEM Microscope 


Institute for Advanced Materials, Devices and Nanotechnology (IAMDN) 


Field Emission TEM/STEM, (JEOL 2010F) 

Acceleration voltage 20-200kV with ZrO-W field emission source 

Scanning Transmission Electron Microscopy (STEM) interface 

Digital imaging with 1Kx1K CCD camera 

BF/DF STEM detectors 

HADF STEM detector 

Electron Energy Loss (EELS) spectrometer 

2Kx2K GATAN imaging EELS filter (GIF) 

Heating (1400K) and cooling (90K) holders 


Electron biprism for holography imaging of magnetic and electrical fields Contact: Frederic Cosandey Professor, Materials Science and 

Engineering 607 Taylor Road, Piscataway, NJ 08854 Telephone: 732-445-4942 , Contact: Philip Batson Professor, IAMDN, Physics, MSE 136 

Frelinghuysen Road, Piscataway, NJ 08854 Telephone: 732-445-5500 x4839 E-mail: batson@physics.rutgers.edu 


Go to http://iamdn.rutgers.edu/facilities 






DISSECTING 

ZEISS/ P.A.L.M. Laser Dissecting Microscope 





department faculty including a Zeiss/P.A.L.M. Laser Dissecting Microscope. The Zeiss P.A.L.M., the Microbeam. Is an inverted fluorescent 

microscope Axiovert 200M equipped with laser micro-dissecting module for contact-free and contamination-free specimen capture from archival 

material to living cells. The system has four objective lenses (Fluar 5x/0.25 NA, Fluar 10x/0.50 NA, Fluar 20x/0.75/NA, and Fluar 100x/1.3 NA) 

and two illumination sources, bright-field and epifluorescence for specimen viewing. For more information see: 

http://www.zeiss.com/C1256D18002CC306/0/1042746EDBB1F8BEC125727D003C07D5/$file/49-0006_e.pdf 




COSTS 

Go to http://genetics.rutgers.edu/content/files/Instruments_ApplicationForm_Fees.pdf 







IMAGING & VISUALIZATION: PET/CT 

Carestream Albira PET/CT 




The Carestream Albira® PET/CT provides two powerful imaging modalities for pre-clinical in vivo molecular imaging. These capabilities include 

Positron Emission Tomography (PET) and X-ray Computed Tomography (CT). The state-of-the-art detector system consists of continuous 

crystals coupled to PSMPTs and advanced PET detector electronics. This PET and CT are ideally suited for quantitative 3D imaging in small 

animal models such as mice and rats. The system is a fully shielded cabinet X-ray system to provide users the safest working environment. 

Researchers can utilize the Albira system for both static and dynamic PET acquisitions which are automatically co-registered with CT for 

anatomical localization of functional imaging data. Because the animal is not harmed during the study, researchers can conduct longitudinal 

studies in oncology, neuroscience, metabolic, and bone diseases. For researchers interested in developing and validating translational 

reporters and probes, this system offers an opportunity to study and validate their probes in vivo using PET tracers which are much more 

readily translatable to clinical environments than optical probes. 



Phone: 

(848) 445-1563 

LOCATION 






IMAGING & VISUALIZATION: PRECLINICAL IMAGING 

Molecular Imaging Center 




Opened in 2012 in new space near the university’s main campus, the Molecular Imaging Center is an advanced facility for Rutgers faculty and 

researchers from industry and other organizations. The center’s equipment includes an MRI system, PET/CT and other imaging systems. 

Expert staff is available for research consultation and user training. 

The Rutgers Molecular Imaging Center is supported by the University-wide AAALAC accredited animal care program managed by Laboratory 

Animal Services. Under the direction of an ACLAM Diplomate Director, the Rutgers animal care program is a registered USDA Research 

Animal Facility and operates under an Animal Welfare Assurance from PHS/NIH. The adjacent animal facilities allow researchers to maintain 

animals for longitudinal imaging studies of any length. 

Research Applications and Services 

• Imaging study and consultation 

- MRI 

- PET / CT 

- MS FX Pro Optical Imaging 

- IVIS Optical Imaging 

- Ultrasound (coming soon) 

• Image reconstruction, 3D display, fusion and quantitative image analysis 

• Training of imaging systems and software applications 

• Animal holding facilities for serial imaging, surgery, anesthesia and veterinary care 



Phone: 

(848) 445-1563 

LOCATION 






IMAGING & VISUALIZATION: ULTRASOUND 

VisualSonices Vevo 2100 




The VisualSonics Vevo ® 2100 is a system with expanded functionality, flexibility and image quality, and operating at frequencies never before 

achieved with solid-state array transducers. The imaging and processing options include Color and Power Doppler Modes for blood flow 

quantification & anatomical identification; M-Mode single line acquisition allowing high-temporal resolution for LV functional analysis; anatomical 

M-Mode for adjustable anatomical orientation in reconstructed M-Mode imaging; 3D-Mode Imaging & volume analysis; nonlinear contrast 

imaging and advanced measurements & quantification. The new MicroScan transducers provide increased frame rates, superb contrast, 

unrivaled resolution and a wider field of view. The system is easy to use, non-invasive and fast, providing extremely high throughput when 

needed. The Vevo high-resolution in vivo micro-imaging systems provides high-resolution imaging down to 30 microns and the ability to easily 

export derived statistical data to any computer for analysis. All areas of research involving phenotypic expression within the small animal model 

can apply the high-resolution, real-time visualization benefits of this system. This includes cardiovascular, cancer biology, neurobioloby, gene 

delivery, nephrology, regenerative medicine, contrast imaging, image-guided injection and 3D visualization and measurement etc. Vevo 2100 

is a redefined state-of-the-art system with a new digital platform delivering outstanding performance in a wide range of applications and animal 

models. 



Phone: 

(848) 445-1563 

LOCATION 






PHYSICAL PROCESSES 

Dissolution Tester D800 Logan Instruments Corp 




Bath dissolution tester ideal for USP dissolution measurements. Key features: 

• 8-Spindle, 8-position configuration 

• Self-centering vessel design, self-calibrating speed and temperature control system 

• Electronic sampling height adjustment at different media volumes 

• Space saving integrated built-in heater/circulator 

• The no-vibration and self-calibrating design ensures all tablets dissolve at the true speed and same temperature 

• An acid-resistant vessel plate and height adjustable platform seals the water tank to limit evaporation 

• Auto-heat setting for preheating the bath 

• Basket & paddle interchangeable shafts 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 




Please contact the facility manager for cost and additional information 


http://www.loganinstruments.com 

LOCATION 







Fitz Mill Roller Compactor 




Fine powders can be processed into densified sheets in the Fitz Mill Roller Compactor by the use of mechanical pressure exerted on two 

counter rotating compaction rolls. The densified sheets can then be granulated to any desired mesh size. 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 






http://www.fitzmill.com/ 

LOCATION 







GeneMachines HiGro Shaker/Incubator 




Machine has four growth chamber towers. Each tower can accommodate 6 deepwell or, 12 standard microwellplates. Temperature, oxygen 

delivery rate, and shaking speed (~600 RPM Max) can be adjusted. 


appointment. 






Phone: 

Phone: 

(732) 932-8165 x127 (732) 932-8165 x215 






Yeast and bacterial growth 


http://www.digilabglobal.com/higro 

LOCATION 







Gericke Feeders DIW KE-87-15VR 




Gericke feeders – DIW KE-87-15VR 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 






http://www.gericke.net 

LOCATION 







Glatt Powder Coater Granulator GPCG1 




A GPCG (Glatt-Powder-Coater-Granulator) from Glatt for processes that are uniform, reproducible and gentle on the product using fluid bed 

techniques. From demanding powder coating to simple drying. Whether granulation/ agglomeration, particle coating or pelletizing. Whether 

spraying from above (Top Spray), from below (Bottom Spray) or from the side (Tangential Spray): simply anything is possible with a GPCG. 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 






http://www.glatt.com/ 

LOCATION 







K-TRON Feeders (KT35, KT20) 




K-TRON single and twin screw volumetric feeders: 

Twin Screw Volumetric Feeders Materials Fed: Twin screw volumetric feeders handle more difficult materials such as pigments, sticky, 

bridging or flooding powders, fiber and fiberglass. 

Twin Screw Microfeeder Materials Fed: For feeding of free flowing to difficult powders (e.g. lumpy, moist, or bridge building materials). 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 

(732) 445-6758 

Engineering C124B 





http://www.ktron.com 

LOCATION 







Kikusui LIBRA2 Tablet Press 




High Speed Medium-sized Tablet Press The reliable production scale rotary press with cGMP compliance. The LIBRA 2 has consistently shown 

an unmatched capacity for compressing difficult products. With its generous 80kN pre-compression capability and wide speed range, the LIBRA 

has proven applicable to the various demands of the customers around the world. 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 




Tablet formation by compression, both single and bilayer 




http://www.kikusui.com/ 

LOCATION 







Schenk Feeders 




Three Schenk Feeders 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 






http://www.schenckamericas.com 

LOCATION 







Vacuum Processing Equipment Envax Products Inc 




The VacuMix vacuum mixer provides the means to combine two or more liquids and/or fillers under vacuum conditions. By mixing in a vacuum 

environment, the end-product will be free of air pockets and bubbles. 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 




• Mixing catalyst into silicones and epoxides 

• Mixing fillers into resins 

• Mixing and degassing in one step 




http://www.envaxproducts.com/ 

LOCATION 






PHYSICAL PROCESSES: DRYING 

Mini Spray Dryer BUCHI B-191 




The Mini Spray Dryer is the laboratory equipment of choice for the quick and gentle drying to powder of liquid end products. The impressive 

features of the Spray Dryer include its efficient performance with very short set-up times, an effective integrated nozzle cleaning mechanism 

and a high degree of flexibility thanks to the different cylinder geometries. Whether the requirement is the gentle drying of natural product 

dyestuffs, the isolation of highly effective pharmaceutical active agents, or the microencapsulation of aromas. The outstanding features greatly 

extends the number of applications that are possible with a spray drying process 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 




• Spray drying from solutions 

• Structure modifications 

• Drying of suspensions 

• Agglomeration 

• Spray crystallization 

• Micro-encapsulation and coating 




http://www.buchi.com/ 

LOCATION 






PHYSICAL PROCESSES: FERMENTATION 

Waksman Institute of Microbiology 

DEPARTMENT NAME Cell and Cell Product Fermentation Facility 


Since its inception in 1951, the fermentation facility's goal has been to provide affordable fermentation services to a highly diverse client base. 

Completely renovated in 2011 the fermentation facility, which meets BL2-LS containment requirements, is comprised of four contiguous 

operation units: 

 

 

 

 

Material Preparation Laboratory 

Fermentation In-Process 

Computer Control 

Product Recovery Room 

Bio-reactor working capacities range from 10 to 800 liters. All systems are computer controlled with algorithm-based cascade-capable PID 

programming. 

In the recovery room, downstream processing includes: 

 

 

 

 

Centrifugation 

Filtration 

Micro and Ultra-filtration 

Cell Disruption 

With the advantage of having the world's pharmaceutical industry in its backyard, a productive climate of industrial liaison has been the 

historical legacy of the facility. Many former facility students and graduates hold positions within the industry. 


Ken Callanan 

fermentation@waksmman.rutgers.edu 

Phone: 

(732) 445-2925 

Fax: 

(732) 445-5735 

190 Frelinghuysen Road. Piscataway, New Jersey 08854-8020 

Website #1: 

http://www.waksman.rutgers.edu/fermentation/home 

Website #2: 

http://fermentation.rutgers.edu/ferment 


For more information, specifications, and instrument availability, please visit our core facility website, and contact us 

(http://waksman.rutgers.edu/ferment) to schedule an appointment. 

LOCATION 

Room 116, Waksman Institute/Rutgers University on the Busch Campus. 

Address: 190 Frelinghuysen Road, Piscataway, New Jersey 08854-8020 





PHYISCAL PROCESSES: POLISHING 

Ion Beam Cross Section Polisher 


Department of Materials Science and Engineering 


The JEOL’s Cross Section Polisher IB-09010CP is routinely used to produce pristine cross sections of samples without smearing, crumbling, 

distorting or contaminating the samples in any way. The samples are fixed to a rotating sample holder that rocks under an argon beam with 

excellent precision. The angle of incidence of the argon beam is such that no surface contamination occurs during milling. 

Key Feature Results 

 

 

 

 

Clean polished cross sections of difficult-to-polish or hard-to-cut samples of hard, soft, and composite materials: powders, films, and 

monoliths 

Clean polished cross sections of samples too sensitive for mechanical polishing 

Clean mirrored surfaces with minimal strain or distortion 

Wide area cross sections (up to several mm across) 


Nathalie Pereira, Ph.D. 

npereira@rci.rutgers.edu 

Phone: 

(732) 932-6850 x603 

Fax: 

(732) 932-6855 671 

US Highway 1, North Brunswick, NJ 08902 


High resolution cross section SEM and FESEM microscopy 

Grain contrast induced by orientation via EBS or EBSD 

EPMA, SAM, EDS, nano-indentation or any other characterization technique requiring polished cross sections 


For sample submission, please contact us via e-mail or phone. 


$375/sample, includes sample preparation and cross polishing 


http://www.jeol.com/PRODUCTS/SamplePreparationEquipment/CrossSectionPolisher/tab... 

LOCATION 

ESRG, 671 US Highway 1, North Brunswick, NJ 08902 





PYHISCAL PROCESSES: MACHINING 

Sarix SX-200 Micro EDM 


Department of Materials Science and Engineering 


The Sarix Micro EDM enables micromachining of conductive work pieces to produce complex designs to high tolerances with feature sizes 

down to 20 microns. A computer aided manufacturing (CAM) module enables high precision positioning, milling, sinking and drilling following 

designs imported from computer aided design (CAD) files in the most commonly used formats. 

Key Feature Results 

 

 

 

 

 

 

 

High precision m-forms and designs 

Concentric and accurate holes, down to 20 micron 

No angle limit 

High quality surface finish (Surface Ra up to 0.05 microns) 

No material alteration or discoloration 

No cracks or deformation 

Working envelope is typically 100 mm in the XYZ Axis 


Nathalie Pereira, Ph.D. 

npereira@rci.rutgers.edu 

Phone: 

(732) 932-6850 x603 

Fax: 

(732) 932-6855 671 

US Highway 1, North Brunswick, NJ 08902 


 

 

High-precision micromachining for fabrication of complex micro-scale pieces 

Can be utilized with any electronically conductive material such as silicon. Even traditionally difficult to machine materials such as 

Titanium, Inconel, Nickel, Carbide and conductive ceramics 


For information and quotes, please contact us via e-mail or phone. Final quote upon review of the required design, materials to be machined 

and tolerances. 


Upon request. 


http://www.sarix.com 

LOCATION 

ESRG, 671 US Highway 1, North Brunswick, NJ 08902 





PHYISCAL PROCESSES: MIXING 

Glatt Multi Axis Blender 




Glatt's patented two axis blending system is a major advancement in bin blending technology. The two axis mixer reduces mixing times and 

significantly improves the blending/mixing process. Through the patented two axis motion, the Glatt TAM system eliminates the need for 

internal baffles within the IBC which reduces cost, improves ergonomics and makes the bin easier to clean. 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 

(732) 445-6758 






http://www.glatt.com/ 

LOCATION 







Liquid Solids Blender The Patterson-Kelley Co. Inc LIB-6919 




Twin-Shell Intensifier Blender provides consistent performance for precise blending, uniformity and efficiency. It features an intensifier bar 

placed at the axis of rotation. The bar’s intensive agitation propels all material into the solids-solids or liquid-solids contacting area. Surface 

action provides the necessary impact, but without excessive work input. 

 

 

 

 

 

Incorporates updated mechanical features while maintaining fast, intimate, high quality blends of even the most minor ingredients 

Sharp angle of discharge helps the operator quickly, efficiently remove blended product 

Intensifier bars promote blending and agglomerating of abrasives, fragiles, lumped materials and heavy or light densities 

Dispersion bar sprays liquids directly into the product at specified times during the process cycle 

Removable intensifier cartridge design allows maintenance to be performed outside the production area; requires only one longlasting 

product seal 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 

(732) 445-6758 






http://www.pkblenders.com/ 

LOCATION 







V-Blender Blend Master 4, 8 and 16 qrt shells Patterson Kelley 




Twin-Shell Intensifier Blender provides consistent performance for precise blending, uniformity and efficiency. It features an intensifier bar 

placed at the axis of rotation. The bar’s intensive agitation propels all material into the solids-solids or liquid-solids contacting area. Surface 

action provides the necessary impact, but without excessive work input. 

 

 

 

 

 

Incorporates updated mechanical features while maintaining fast, intimate, high quality blends of even the most minor ingredients 

Sharp angle of discharge helps the operator quickly, efficiently remove blended product 

Intensifier bars promote blending and agglomerating of abrasives, fragiles, lumped materials and heavy or light densities 

Dispersion bar sprays liquids directly into the product at specified times during the process cycle 

Removable intensifier cartridge design allows maintenance to be performed outside the production area; requires only one longlasting 

product seal. 


Eric Erenrich 


Phone: 

(732) 445-6711 

Fax: 

(732) 445-6758 






http://www.pkblenders.com/ 

LOCATION 






PCR TOOLS 

StepOnePlus Real-Time PCR System 




The StepOnePlus Real-Time PCR System is a 96-well Real-Time PCR instrument perfect for both first-time and experienced users. The 

StepOnePlus uses an LED-based four-color optical recording system that reads fluorescence from FAM⁄SYBR® Green, VIC®⁄JOE, 

NED⁄TAMRA, and ROX dyes. 






Phone: 

Phone: 

(732) 932-8165 x127 (732) 932-8165 x215 






The StepOnePlus System supports many Real-Time PCR applications: 

 

 

 

 

 

 

 

 

 

 

 

SNP genotyping - Gene expression analysis 

microRNA expression 

Protein expression 

Translocation analysis 

Gene detection A variety of analysis methods are available with the StepOnePlus including: 

Standard curve (absolute quantitation) 

Relative standard curve 

Comparative Ct (∆∆Ct) 

Genotyping and presence/absence 

Melt curve analysis (available as a standalone application) 

High resolution melting (available as a standalone application) 


For more information, specification, and instrument availability, please visit our core facility website, and contact us to schedule an appointment. 



appointment. Non-Rutgers: $ 20 / run 


LOCATION 






REPOSITORY 

Rutgers University Cell and DNA Repository (RUCDR) 

RUCDR Infinite Biologics 


Rutgers University Cell & DNA Repository www.RUCDR.com 


Sample Collection / Logistics Services 

Customized sample collection kits 

SOPs and training materials for sample collection 

Real-time registration and tracking of sample submission 

Biomaterial Sample Processing Services 

Isolation and cryopreservation of tissue samples 

Automated blood fractionation 

Nucleic Acid Services 

Automated DNA and RNA extraction from a variety of sources including : whole blood, cell lines, blood spot cards, frozen tissues, 

FFPE tissue, serum, plasma and saliva 

Nucleic acid amplification 

Comprehensive analytical and functional quality control 

Cell Culture Services 

Isolation and cyropreservation of primary source cells from tissue 

Reprogramming of primary fibroblast, blood lymphoblast cells to induced Pluripotant stem cells (iPSCs) 

Lymphocyte transformation from whole blood and cryopreserved PBMCs 

Fibroblast cell line establishment from tissue 

Extensive genotypic and phenotypic characterization of primary, transformed and iSPC lines 

Storage in heat-sealed glass or plastic ampules 

Bioinformatics and Analytical Services 

Web based enterprise-level LIMS with real-time sample/service tracking 

Study design and statistical genetics consultation 

Comprehensive genotyping 

Epigenetic analyses 

Whole transcriptome analyses 

DNA copy number analyses 

DNA/RNA "fingerprinting" 

Diagnostic tests for common disease variance 

Sample Storage Services 

4° C, -20° C, 80° C mechanical storage 

Liquid nitrogen storage in either vapor or liquid phase 

Real-time temperature and security monitoring (24/7/365) 


support@rucdr.org 

Phone: (732) 445-1498 

Fax: (732) 445 1149 

WEBSITE: www.rucdr.org 

LOCATION 

604 Allison Road Piscataway, NJ 08854 





MICROELECTRONICS RESEARCH LABORATORY (MERL) 


Rutgers University Microelectronics Research Laboratory (MERL) http://www.merl.rutgers.edu/ 


The Microelectronics Research Laboratory closely works with researchers in academic, government and industry to help solve 

problems in multidisciplinary science and engineering and high-tech industry to carry out advanced research in micro- and nanooptoelectronics, 

solid state devices and electronic materials. The capabilities of the laboratory include a dry processing area for plasma 

processing, thin film metallization and dielectric, thermal processing, ultraviolet lithography, nano-imprint and most recently atomic layer 

deposition. 


Warren Lai MERL Associate Director warren.lai@rutgers.edu (732) – 445-0680 

LOCATION 98 Brett Rd Rutgers University-Bush Piscataway, NJ 08854 

Rates* 

Equipment 

Description 

($/hr) 

Some with multiple units External Rutgers 

* Listed are typical rates. 

MERL offers lower rates (monthly, contract, fee caps, membership, price 

match) based on usage. 

Facility Access: Entitles user to all equipments except: 60 30 

a. equipment with hourly rate listed separately below 

b. excessive or expensive consumables, precious metal and gases 

c. overlong or special processes 

Lithography 

Karl Suss Contact Printer Photolithography Contact Printer 70 35 

Nanonex Nanoimprint System Nanolithography Nanoimprint System 50 25 

Laurell Spin Coater Manual Photoresist Spin Coater 0 0 

Thermolyne Hot Plate Hot Plate Unit 0 0 

Cole Palmer Hot Plate Digital Hot Plate & Stirrer 0 0 

Dexon Process Bench 

Photolithography Chemical Process 

Bench 

0 0 

Ultra Tech Mask Cleaner Photo Plate Cleaner 0 0 

Deposition 

Varian E-Beam System Evaporation Deposition 70 35 

Plasma Therm PECVD 

Plasma Enhanced Chemical Vapor 

Deposition 

70 35 

Unaxis PECVD 

Plasma Enhanced Chemical Vapor 

Deposition 

70 35 

System Design Sputter Machine Sputter Deposition 70 35 

Denton Sputter Machine Sputter Deposition 70 35 

Spire MOCVD System 

Metal Organic Chemical Vapor 

Deposition 

70 35 

Ge MOCVD System 

Ge Metal Organic Chemical Vapor 

Deposition 

70 35 

Wet Chemistry/Etch 

Wet Etch Bench Dexon Process Benches 0 0 

Glove Box Hazard Process/Controlled Enclosures 0 0 

STI Semitool Spin Dryer Automated Spin Dryer 0 0 





MICROELECTRONICS RESEARCH LABORATORY (continued) 

Dry Etch & CMP 

Unaxis Etcher Device Process Dry Etcher 70 35 

Trion Gas Etcher Device Process Dry Etcher 70 35 

Ecomet Polisher Chemical Mechanical Polisher 0 0 

Thermal Process 

Thermco Furnace Tubes Oxidation/Diffusion/Annealing Furnace 0 0 

Lindberg Furnace Multi Process Furnace Tube 0 0 

Heatpluse RTA System Rapid Thermal Anneal 0 0 

Blue-M Box Ovens Process Dehydration Ovens 0 0 

GCA Vacuum Oven Process Vacuum Oven 0 0 

Thermotron Chamber Burn In Chamber 0 0 

Metrology/Inspection 

ISI SEM (microelectronics) Scanning Electron Microscope 60 30 

Hitachi FESEM (nanoelectronics) 

Field Emission Scanning Electron 

Microscope 

140 70 

Leitz Microscope Multi Function Inspection Microscope 0 0 

Nanometrics Film Thickness Film Thickness Measurement 0 0 

Dektak Alpha Prolifometer Surface Profiler 0 0 

Nanoline Linewidth Measurement Linewidth Measurement 0 0 

Particle Inspection Unit Particle Analyzer System 0 0 

Nikon MicroPattern Align Analyzer 

Mask Inspection System For Photo 

Plates 

0 0 

Backend 

Hybond Wire Bonder Manual Device Wire Bonder 0 0 

K&S Wire Bonder Device Packaging 0 0 

Microautomation Dicing Saw Device Separation Dicing Saw 0 0 

Test 

Magne-Tron Probe Device - 4 Point Probe 0 0 

Electroglass Probe Automated Electronics Probe Station 0 0 

Temp Vacuum System 

High Voltage-Temperature Vacuum 

System 

0 0 

Hall Effect Electromagnet Hall Effect Measurement 0 0 

Technical Support Personnel support beyond normal need 100 50 





ROBOTICS 

SGA Robotics: RoToR HDA 




The RoToR HDA is a very small benchtop robot for easy ultra-fast manipulation of high density arrays of yeast or bacteria. The RoToR uses 

plastic replica plating pads and supports liquid pinning to and from 96- and 384-well microtitre plates and agar pinning at densities 96, 384, 768, 

1536, 3072, and 6144. The RoToR HDA is very fast and can process up to 100 plates per hour. It is user-friendly and is very easy to use. It 

supports 96- and 384-well liquid-liquid / liquid-agar / agar-liquid spotting. It allows replication, arraying, mating and breakdown at 96, 384, 768 

and 1536 density. It can dispense to and from solid or liquid media in 96- and 384-well formats with a throughput of up to 100 plates per hour. It 

is compatible with all SBS format plates/trays and shallow multi-well plates 






Phone: 

Phone: 

(732) 932-8165 x127 (732) 932-8165 x215 






Use reagents such as the yeast deletion mutant strain collection for large-scale yeast two-hybrid, synthetic genetic array, phenotypic, and 

chemical-genetic screening analysis. 



appointment. 

COSTS OUTSIDE RUTGERS $ 80 /hr 


http://www.singerinstruments.com/index.phpoption=com_content&task=view&id=16&It... 

LOCATION 



Rutgers Office of Research Alliances: Contact Us 

Thomas Richardson, PhD, MBA 

Director, ORA 

732‐445‐0320 

thomrich@vpr.rutgers.edu 

Tom leads ORA and focuses on long‐term strategy and oversight of the 

group. He also has domain expertise in the life sciences with over 12 

years experience in scientific and business roles. He worked as one of 

the early scientists at a Boston‐based start‐up that went public and 

moved to a business development and licensing role at a mid‐sized 

biotech in Princeton that was ultimately acquired. Most recently, he 

oversaw licensing in the life sciences at Rutgers office of technology 

commercialization. He has a PhD in biochemistry from Boston 

University School of Medicine and completed a post‐doctoral fellowship 

in biomaterials at the University of Michigan. 

David Sadowski, MS 

Associate Director, ORA 

732‐445‐3344 

d.sadowski@rutgers.edu 

David serves as a liaison to many internal and external partners. He 

fields requests from schools and departments, interdisciplinary 

programs, technology centers and companies in order to connect 

resources and create partnerships in scientific fields distinct from life 

sciences and information technology. Prior to joining ORA in 2011, 

David served in a variety of customer service‐oriented positions, 

including Assistant Vice President of the University of Rhode Island, 

Deputy Director of the NIH Office of Technology Transfer DTDT, Patent 

Advisor at USDA and as a Primary Patent Examiner in the United States 

Patent and Trademark Office. 

James Mielke, MBA 

Associate Director, ORA 

732‐445‐2229 

james.mielke@rutgers.edu 

James connects Rutgers Research with industry and provides business 

layer support to faculty. With a focus on Information Technology and 

Computer Science, his corporate portfolio includes a wide band of 

industries, namely pharmaceuticals, biotechnology, finance, IT, 

aerospace and media. After 13 years in the IT industry working primarily 

for financial, biotech and pharmaceutical firms, James joined Rutgers in 

2011. In addition to his duties within the ORA, he is presently serving as 

the Deputy Director of the Center for Dynamic Data Analytics. James 

holds an MBA from Penn State and maintains an MCSE certification. 

Chris Perkins 

Program Coordinator, ORA 

732‐445‐2226 

christopher.perkins@rutgers.edu 

Chris joined the ORA team in 2011 after earning a B.A. in journalism 

from Penn State University. Utilizing his marketing and communications 

background, he handles a great deal of the day‐to‐day administrative 

business for ORA. In addition to coordinating meetings, conducting 

outreach to speakers and arranging presentations, he is also 

responsible for maintaining web content, print publications and social 

media outreach. 

ora.rutgers.edu linkd.in/RutgersResearch @RutgersResearch 

Contact Edward Tate for media and communications inquiries regarding Rutgers research. 

732‐ 445‐3153 

edward.tate@rutgers.edu

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