PART 5_2 Chemical contaminants and ecotoxicology
PART 5_2 Chemical contaminants and ecotoxicology
PART 5_2 Chemical contaminants and ecotoxicology
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Internal dosimeters-<br />
1. measure the amount of a toxicant or its metabolite<br />
present in cells, tissues, or body fluids. Ex.<br />
urinary nitrophenol concentration used as a<br />
marker for methyl parathion exposure.<br />
2. account for individual differences in absorption<br />
<strong>and</strong> bioaccumulation of the xenobiotic <strong>and</strong> are<br />
relatively easy to measure.<br />
The biologically effective dose is the amount of the<br />
internal dose necessary to elicit a response or<br />
health effect.