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BIO DATA - University of Karachi

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Name : Naheed Akhtar<br />

<strong>BIO</strong> <strong>DATA</strong><br />

Father’s Name : Mohammad Ismail Qureshi<br />

Present position : Pr<strong>of</strong>essor and Chairperson<br />

Department <strong>of</strong> Biochemistry<br />

<strong>University</strong> <strong>of</strong> <strong>Karachi</strong><br />

Address : B/189/Block “A” North Nazimabad,<br />

<strong>Karachi</strong>, Pakistan.<br />

Date <strong>of</strong> Birth : May 08, 1952.<br />

N.I.C. No. : 42101-1500410-8<br />

Religion : Islam<br />

Phone No : 36639604<br />

Email : nakhter@uok.edu.pk<br />

mohdfasieh@hotmail.com<br />

Qualification :<br />

Examination<br />

Subject<br />

Year <strong>of</strong> Passing Division Institution Main Subject<br />

Matric 1967 1 st <strong>Karachi</strong> Board Biology,<br />

Chemistry and<br />

Physics<br />

Intermediate 1970 2 nd <strong>Karachi</strong> Board Biology<br />

Chemistry<br />

Physics<br />

B.Sc (Hons) 1973 2 nd Uni. <strong>of</strong> <strong>Karachi</strong> Biochemistry<br />

Chemistry<br />

Physiology<br />

M.Sc 1974 1 st Uni. Of <strong>Karachi</strong> Biochemistry<br />

M.phil 1980 Uni. Of <strong>Karachi</strong> Biochemistry<br />

Ph.D 1988 Uni. Of <strong>Karachi</strong> Biochemistry<br />

Teaching Experience:<br />

Cooperative Teacher : Sept. 1980 to December 1982.<br />

Jan 1986 to December ,1986.<br />

Lecturer: : Jan. 1988 to September , 1991.<br />

Department <strong>of</strong> Biochemistry<br />

<strong>University</strong> <strong>of</strong> <strong>Karachi</strong>


Assistant Pr<strong>of</strong>essor : Sept. 1991 to August, 1997.<br />

Department <strong>of</strong> Biochemistry<br />

<strong>University</strong> <strong>of</strong> <strong>Karachi</strong><br />

Associate Pr<strong>of</strong>essor : Aug. 1997 to 31-12-2000<br />

Department <strong>of</strong> Biochemistry<br />

<strong>University</strong> <strong>of</strong> <strong>Karachi</strong><br />

Pr<strong>of</strong>essor : January 01, 2001 to date<br />

Department <strong>of</strong> Biochemistry<br />

<strong>University</strong> <strong>of</strong> <strong>Karachi</strong><br />

Chairperson : January 2009 to date<br />

Department <strong>of</strong> Biochemistry<br />

<strong>University</strong> <strong>of</strong> <strong>Karachi</strong><br />

Research Experience :<br />

M.Phil : 1976 to 1980<br />

Ph.D : January 1983 to December 1985.<br />

Scholarship Awarded :<br />

1 : Scholarship from university <strong>of</strong> Grant Commission Islamabad for M.phil.<br />

2: Scholarship from <strong>Karachi</strong> university for Ph.D<br />

LIST OF MS/Ph D AND Ph D STUDENTS (Supervisor not Approved by HEC)<br />

S.No Name <strong>of</strong> Student Admission<br />

1 Ms Afshan Naz Ph.D Submitted<br />

2 Ms Atia Masood Ph.D Submitted<br />

3 Ms Farhat Bano Ph.D Writing Thesis<br />

4 Ms Khalida Bano Ph.D Writing Thesis<br />

5 Mr Asnad Ahmed Ph.D Writing Thesis<br />

6 Mrs Ambreen Faiyaz M.Phil/Ph.D<br />

7 Ms Bushra Bilal MS/Ph.D<br />

8 Dr.Syed Danish MS/Ph.D<br />

9 Ms Tahira Ph.D<br />

10 Mrs Uzma Asif MS/Ph.D<br />

11 Mr Asif Khan MS/Ph.D<br />

12 Mrs Hoor Fatima Ms/PhD


Publications:<br />

1: Naheed Akhtar and M.A. Haleem. (1985): Studies on the structure <strong>of</strong> b-chitin. 3rd<br />

International conference on chitinand chitosan (ITALY).<br />

2: Naheed Akhtar and M.A.Haleem (1990): Studies on the structure <strong>of</strong> b-chitin:<br />

Z.Naturforsch.,45b:87-92<br />

3: M.Ismail ,Naheed Akhtar,I.M.Kidwai and M.A.Haleem.(1991): Potential energy calculations<br />

<strong>of</strong> 2-formyl-4-morpholino pyridine thio semicarbazone as an anti tumor drug. Pak.J.Pharmacol.,<br />

9(1): 41-44.<br />

4: Ateeq Farhana,Naheed Akhtar,I.M.Kidwai and M.A.Haleem.(1991): Studies on the structure<br />

<strong>of</strong> b-chitin. in:International sym.on contemp.biol.,Islamabad.,pp.103<br />

5: K.Perveen,N.Akhtar,I.M.Kidwai and M.A.Haleem.(1992): Potential energy calculations <strong>of</strong><br />

metyrapone. in:Proc.Ist.Nat.Biochem.Sym.,<strong>Karachi</strong>, Pakistan.<br />

6: Farhat Deeba,N.Akhtar,I.M.Kidwai and M.A.Haleem.(1992): Studies on the structure <strong>of</strong><br />

cellulose II , in:Proc.Ist.Nat.Biochem.Sym.,<strong>Karachi</strong>, Pakistan.<br />

7: M.A.Haleem and N.Akhtar .(1992): Refinement <strong>of</strong> triple helical structure <strong>of</strong> b-D-1,3 xylan.<br />

in:Proc.Ist.Nat.Biochem.Sym.,<strong>Karachi</strong>, Pakista<br />

8: N.Akhtar and M.A.Haleem.(1992): Studies on the structure <strong>of</strong> b-chitin.<br />

in:Proc.Ist.Nat.Biochem.Sym.,<strong>Karachi</strong>, Pakistan ed: S.N. Hasnain, M.A. Haleem, H.S.A. Athar,<br />

pp 113-119.<br />

9: M. Ismail, Naheed Akhter, I.M. Kidwai and M. A. Haleem (1992): Potential energy<br />

calculations <strong>of</strong> 2-formyl-4-morpholino pyridinethio semicarbazone as an-antitumor drug. Pak. J.<br />

Pharmacol, 9(1) 41-44<br />

10: Noor Jehan,N.Akhtar,I.M.Kidwai and M.A.Haleem.(1992): Potential energy calculations <strong>of</strong><br />

2-formyl-4-morpholino-pyridine thio semicarbazone. in:Proc.Ist.Nat.Biochem.Sym.,<strong>Karachi</strong>,<br />

Pakistan.ed: S.N. Hasnain, M.A. Haleem, H.S.A. Athar, pp 120-124.<br />

11: N.Akhtar and M.A.Haleem (1992): Rigid refinement <strong>of</strong> triple helical structure <strong>of</strong> b-D-1,3<br />

xylan in.Proc. Ist.Int.Conf. <strong>of</strong> Pharmaceutical Sciences.<strong>Karachi</strong>. pp.23. Ist.Int.Conf. <strong>of</strong><br />

Pharmaceutical Sciences.<strong>Karachi</strong>. pp.23.<br />

12: K.Perveen,N.Akhtar, I.M.Kidwai and M.A.Haleem.(1993): Potential energy calculations <strong>of</strong><br />

metyrapone.


Kar.Uni.J.Sc.,21(1-2):201-205.<br />

13: M.K.Azim, Naheed Akhtar and M.A.Haleem.(1993): Computer aided conformational<br />

analysis <strong>of</strong> psychoactive agent:amoxapine. in: 2nd.Nat.Biochem.Sym.,Hyderabad,Pakistan.,pp.9.<br />

14: A. Khatoon, N. Akhter, I.M. Kidwai and M. A. Haleem (1993): Potential energy calculations<br />

<strong>of</strong> methyl-a-thiomaltoside. Pak. J. Scie. Ind. Res. 36(12), 517-519<br />

15: M.K. Azeem, Naheed Akhter and M. A. Haleem (1994): Computer aided conformational<br />

analysis <strong>of</strong> psychoactive agent: amoxipine. Proc. ISBBP Symposium Biochem.Biophysics<br />

(<strong>Karachi</strong>) 1, 40-43.<br />

16: M. Zehra, N. Akhter, I. M. Kidwai and M. A. Haleem (1994): Conformational studies <strong>of</strong><br />

Gallamine Triethiodide: a neuromuscular blocking agent. Proc.ISBBP Symposium<br />

Biochem.Biophysics ( <strong>Karachi</strong>) 1, 99-102<br />

17: F. Zaheer, N. Akhter, I. M. Kidwai, Z. A. Saify and M. A. Haleem (1994): Conformational<br />

analysis <strong>of</strong> Loxapine: a psychoactive drug. Proc. ISBBP Symposium Biochem.Biophysics<br />

(<strong>Karachi</strong>) 1, 127-130<br />

18: M. A. Haleem, F. Deeba and Naheed Akhter (1994): Computational studies on the structure<br />

<strong>of</strong> cellulose II. Proc. ISBBP Symposium Biochem.Biophysics (<strong>Karachi</strong>) 1, 165-168.<br />

19: M.Ismail,N.Akhtar,I.M.Kidwai and M.A.Haleem (1994): Potential energy calculations <strong>of</strong><br />

(Rs)-1,4-dibenzoyl-cis-2,5 dimethyl piperazine. Kar.Univ.J.Sc. 22(1&2):101-107.<br />

20: M.Ismail, N.Akhtar,I.M.Kidwai and M.A.Haleem(1995): Potentential energy calculations <strong>of</strong><br />

4'-fluoro-4-[4-(2-pyridyl)-1-piperazinyl] butyrophenone (azaperone). Kar.Uni.J.Sc.23(1&2), 81-<br />

87.<br />

21: M. A. Haleem, N. Akhtar and M. Zehra (1997): Conformational analysis <strong>of</strong> opiate alkaloid<br />

(7-(1-cyclohexyl-1-hydroxyethyl)-16-ethyl-6,14-endo- 6,7,8,14-tetrahydro-3-oripavinyl methyl<br />

ether. Proc. ISBBP Symp. Biochem. Biophys.2, 55-57.<br />

22: M. A. Haleem, M. Zehra, I. M. Kidwai, Z. S. Saify and N. Akhtar (1997): Conformational<br />

analysis <strong>of</strong> histamine H-1 receptor antagonist. Proc. ISBBP Symp. Biochem. Biophys.2, 283-<br />

286.<br />

23: N. Akhtar, N. Fatima, I. M. Kidwai and M. A. Haleem (1999): Computer aided<br />

conformational analysis <strong>of</strong> antihistamine drug chlorpheniramine maleate. Hamdard Medicus XIII<br />

(2), 69-71.<br />

24: Naheed Akhtar ,Imran Aslam and M.A.Haleem (2001): Computer aided conformational<br />

analysis <strong>of</strong> thebaine. Hamdard Medicos XLIV(1). 96-98.


25: Waseem Ahmed, Naheed Akhtar and M. A. Haleem (2002): Computer aided conformational<br />

analysis <strong>of</strong> histamine H1 receptor antagonists. Pak J. Biochem and Mol Biol. 35 (2) 60-62.<br />

26: Waseem Ahmed, Nahid Akhtar and M. A. Haleem (2003): Conformational analysis <strong>of</strong> 3{4-<br />

(5-Bromo-3 methy1 pyrid-2-yl-buty1 amino-4-(benzylamino-1,2,5-thiadiazole-1-oxide. Pak J.<br />

Biochem and Mol. Biol 36 (1), 40-44.<br />

27: Farhat Bano, Naheed Akhtar and M. A. Haleem (2003): Computer aided conformational<br />

analysis <strong>of</strong> P I (diethylene triamine) guanosine} (CIO4)2. Pak J. Biochem and Mol Biol 36 (1),<br />

24-26.<br />

28: Sadaf Naeem ,Naheed Akhtar ,Waseem Ahmed ,Farhat Bano and M.A.Haleem (2004)<br />

Conformational Analysis <strong>of</strong> 2-( a -D-lyx<strong>of</strong>uranosyl) Maleimide . Pak.J.Pharmacol. 21(1),31-36.<br />

29: Waseem Ahmed ,N.Akhtar and M A Haleem(2004) . Conformational analysis <strong>of</strong> 2(4-(5bromo-Methyl<br />

pyridyl)butyl amino)-4-pyrimidone. Hamdard Medicus XLVII(1),50-53.<br />

30: N.Akhtar,S.Naeem,F.Bano,W.Ahmed and M.A.Haleem(2004) . Conformational analysis <strong>of</strong> [<br />

Pd(diethylene triamine )(guanosine)](ClO4)2 . Hamadard Medicus XLVII(3),133-135<br />

31: N.Akhtar,S.Haseen ,I.M.Kidwai and M.A.Haleem(2004). Computer aided conformational<br />

analysis <strong>of</strong> 2-Deoxy-3-5-di-o-acetyl Adenosine . Hamdard Medicus XLVII(2),52-53.<br />

32: N.Akhtar,S.Naeem,W,Ahmed and M.A.Haleem (2004). Rigid body refinement <strong>of</strong> water<br />

mediated triple helical structure <strong>of</strong> b - D-1,.3 xylan from Palmaria Palmata (L.)Kuntze,<br />

Rhodophyta . Pak.J.Botany 36(4),745-750.<br />

33: W.Ahmed, N.Akhtar and M.A.Haleem (2004). Conformational analysis <strong>of</strong> temalastine<br />

<strong>Karachi</strong> <strong>University</strong>. Journal <strong>of</strong> Science 32(1-2):1-5<br />

34: Khalida Bano, Najaf Abbas Ghafoor, Naheed Akhtar.(2005) .Conformational Analysis <strong>of</strong><br />

Cimitidine .(poster Presentation) (poster Presentaion) at 8 th Biiennial National Conferenec <strong>of</strong><br />

Pakistan Society for Biochemistry and MolecularBiology<br />

35: Afshan Naz, Naheed Akhtar(2005) . Poster on Conformational Analysis on Antitumor Drugs<br />

Showdomycin, 8 th National Biennial Conference In Biochemistry Department <strong>Karachi</strong> <strong>University</strong><br />

On 2005.<br />

36Farhat Bano, Sadaf Naeem, Naheed Akhtar and M.A Haleem (2005). Computer aided<br />

conformational analysis <strong>of</strong> sulfonated Azo Dyes Diammonium orange (C16<br />

H10N2O7S2(NH4).4H2O. pak.J. <strong>of</strong> pharma Sci.18(3):66-70.<br />

37: Afshan Naz, Farhat Bano Sadaf Naeem, Naheed Akhtar and M.A.Haleem (2006). Computer<br />

Aided Conformational Analysis Of Diazepam (7-Chloro-1.3-Dihydro-1-Methyl-5-Phenyl-2H-4-<br />

Benzodizapine-2-One). 1NT. J. <strong>BIO</strong>TECH., 3(1): 145-149.


38: Khalida Bano, Zaheer-ul-Haq, Naheed Akhtar(2008). 3D QSAR analysis on<br />

acylpiperazines as Histamine H3 Receptor Antagonists 11 th INTERNATIONAL SYMPOSIUM<br />

ON NATURAL PRODUCT (Poster)<br />

39: Khalida Bano, Zaheer-ul-Haq, Naheed Akhtar (2008). CoMFA and CoMSIA 3D QSAR<br />

analysis on acylpiperazines as a New Class <strong>of</strong> Imidazole-Free Histamine H3 Receptor<br />

Antagonists.. 35 th all Pakistan science conference .(oral)<br />

40: Khalida Bano, Sana Farman, Farhat Bano, Naheed Akhtar (2008).Conformational Analysis<br />

<strong>of</strong> Histamine H2 Receptor’s Antagonist”Temalastine” as a Cimetidine Derivative by Argus lab<br />

4 s<strong>of</strong>tware. 35 th all Pakistan science conference.(oral)<br />

41: Khalida Bano, Naheed Akhtar ,Najaf Abbas Ghafoor, M.A. Haleem. (2008) Conformational<br />

Analysis <strong>of</strong> Histamine H1- Receptor Antagonist “Temalastine” as a Cimetidine Derivative. Int.<br />

J. Biol. Biotec. 2008: 5(1);93-100.<br />

42: Afshan Naz, Naheed Akhtar, Khalida Bano, Najaf Abbas Ghafoor , Farhat Bano ( 2009).<br />

Conformational Analysis (Geometry optimization ) <strong>of</strong> Nucleosidic Antitumor Antibiotic<br />

Showdomycin by Arguslab 4 S<strong>of</strong>tware. Pak.J.Pharm. Vol 22. pp.78-82.<br />

43: Farhat Bano, Kahalida Bano, Naheed Akhtar, M.A. Haleem (2009) Potential energy<br />

calculation <strong>of</strong> antimuscaranic-6-methyl-6-azabicyclo[3-2-1]octainol-2,2-diphenyl propionate.<br />

Pak.J. Biochem. Mol. Biol. 42(4); 178-182.<br />

44: Khalida Bano, Afshan Naz, Nazia Akber, Ambreen Faiyaz, Naheed Akhtar (2010)<br />

.Conformational Analysis <strong>of</strong> Flavanoid Derivatives as Histamine H1 Receptor Antagonist. .<br />

Pakistan Journal Of Biochemistry and Molecular Biology. 43(3): 109-113.<br />

45: Khalida Bano, Riffat Touheed ,Sana Farman , Najaf Abbas Ghafoor and Naheed<br />

Akhtar(2010). Computer Aided conformational Analysis <strong>of</strong> β- Blocker /Vasodilator Agent<br />

Prizidilol. Pak.J.Biochem.Mol.Biol.2010:43(4).<br />

46: Zafar S. Saify , Afshan Naz, Naheed Akhter, Khalida Bano (2010). Molecular Docking study<br />

Of Tiaz<strong>of</strong>urin Analogues as Human Nicotinamide / Nicotinic acid mononucleotide<br />

Adenylytransferase inhibitors. Int. J. Mol. Sci. 2010, 11,<br />

(1doi:10.3390/ijms110x000x)(accepted).<br />

47: Khalida Bano, Najaf Abbas Ghafoor, Naheed Akhtar.(2010). Comparative Studies <strong>of</strong><br />

Cimetidine Derivative “Temalastine” for Potential Energy Calculation By Kitaigorodskii and<br />

Lennard –Jones Functions. Pak.J.Biochem.Mol.Biol.2010:43(1).


48: Farhat Bano, Naheed Akhtar, Hajra Naz (2011) Effect <strong>of</strong> the Aqueous Extract <strong>of</strong><br />

MOMORDIC CHARANTIA on Body Weight <strong>of</strong> Rats.. Journal <strong>of</strong> Basic and Applied Sciences,<br />

Vol.7, No1, 1-5, 2011<br />

49: Khalida Bano, Amber Yaseen, Mohammad Farhan , Najaf Abbas Ghafoor, Naheed<br />

Akhter(2011). Conformational Analysis <strong>of</strong> Ciproxifan as a Histamine H3 Receptor Antagonist.<br />

Pak.J. Biochem. Mol. Biol..(accepted)<br />

50: Khalida Bano , Mohammad Farhan , Naheed Akhter (2010) Conformational Analysis and<br />

Docking studies <strong>of</strong> Ciproxifan as a Histamine H3 Receptor Antagonist. (Poster presentation) at<br />

10 th Biiennial National Conferenec <strong>of</strong> Pakistan Society for Biochemistry and MolecularBiology.<br />

51: Khalida Bano, Kulsoom Javaid, Naheed Akhtar. (2011). Molecular Docking Studies and<br />

Conformational Analysis <strong>of</strong> 1 –Alkyle- 4-Acylepiperazine Derivative As A Imidazole free H3<br />

Receptor Antagonist 3 rd International Symposium Cum Training Course on Molecular Medicine<br />

and Drug Research .3 rd to 6 th January 2011.<br />

52: Khalida Bano Abbas, Afshan Naz, Ayesha Khan, Farhat Bano, Naheed Akhtar(2011) .<br />

Moloecular Docking And Geometry Optimization <strong>of</strong> Phenstatin, A Benzophenone Analogue<br />

Use As An Anti Cancer Drug. Symposium cum Workshop on Tools in Biomedical Research,<br />

Golden Jubilee Celebrations. Department <strong>of</strong> Biochemistry, <strong>University</strong> <strong>of</strong> <strong>Karachi</strong> . 1 st -3 rd March<br />

2011.<br />

53: Najaf Abbas Ghafoor, Khalida Bano Abbas , Naheed Akhtar, M. A. Haleem (2011)<br />

Conformational Analysis And Geometry Optimization <strong>of</strong> Codeine Hydro Bromide Dihydrate, As<br />

A Morphine Derivative. Symposium cum Workshop on Tools in Biomedical Research, Golden<br />

Jubilee Celebrations. Department <strong>of</strong> Biochemistry, <strong>University</strong> <strong>of</strong> <strong>Karachi</strong> .<br />

54: Khalida Bano Abbas , Najaf Abbas Ghafoor, Ambreen Faiyaz , Naheed Akhtar, M.A.<br />

Haleem.(2011) Conformational Analysis And Geometry Optimization <strong>of</strong> 2-[Benzyl-N-2-<br />

Pyridyl Amino Propylamino]-4-Pyrimidone , Cimetidine Derivative as a Histamine H2 Receptor<br />

Antagonist Drug . Symposium cum Workshop on Tools in Biomedical Research, Golden Jubilee<br />

Celebrations. Department <strong>of</strong> Biochemistry, <strong>University</strong> <strong>of</strong> <strong>Karachi</strong> . 1 st -3 rd March 2011<br />

55: Sehrish Aziz, Afshan Naz, Naheed Akhtar.(2010) . Molecu7lar Docking study and<br />

Conformational Analysis <strong>of</strong> Temozolomide inhibitor (as Brain antitumor agent) by using Argus<br />

Lab S<strong>of</strong>tware. (Poster presentation) at 10 th Biiennial National Conferenec <strong>of</strong> Pakistan Society for<br />

Biochemistry and MolecularBiology.<br />

56: Chaudhary, A.M.A, Akhtar, N.(2008).Three dimensional quantitative structure activity<br />

relationship <strong>of</strong> 3-[3-9N-4-Fluroenzyl-N-2 pyridylamino]-4-Ethylamino-1,25-Thiazole-1-Oxide<br />

(Histamine H1 receptor antagonist ) as an antiulcer and anti allergy. Inte. J. Biol. Biotec. 5(3-4):<br />

197-210, 2008


57: Khalida Bano, Asnad Ahmed, Najaf Abbas Ghafoor, Ambreen Faiyaz, Naheed Akhter(2011)<br />

. Conformational Analysis and Geometry Optimization <strong>of</strong> Amlodipine Besylate (NORVASC) as<br />

a Vasodilator. . Pak.J.Biochem.Mol.Biol.

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