림프구성 누두신경뇌하수체염：증례 보고 및 문헌고찰
림프구성 누두신경뇌하수체염：증례 보고 및 문헌고찰
림프구성 누두신경뇌하수체염：증례 보고 및 문헌고찰
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KISEP Case Reports J Korean Neurosurg Soc 29822-825, 2000<br />
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<strong>림프구성</strong> 누두신경뇌하수체염:증례 <strong>보고</strong> <strong>및</strong> <strong>문헌고찰</strong><br />
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손영제·왕규창·최기영<br />
*·지제근<br />
*·조병규<br />
= Abstract =<br />
Lymphocytic InfundibuloneurohypophysitisCase Report and Review of the Literature<br />
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Young-Je Son, M.D., Kyu-Chang Wang, M.D., Gheeyoung Choe, M.D.,*<br />
Je Keun Chi, M.D.,* Byung-Kyu Cho, M.D.<br />
Department of Neurosurgery and Pathology,* Seoul National University College of Medicine ,Seoul, Korea<br />
Neuroscience Research Institute, Seoul National University Medical Research Center, Seoul, Korea<br />
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KEY WORDS <br />
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서 론<br />
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증 례<br />
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822<br />
J Korean Neurosurg SocVolume 29June, 2000
손영제 · 왕규창 · 최기영 · 지제근 · 조병규<br />
Fig. 1. T1-weighted MR image showing loss of high signal in neurohypophysisleft and strong homogeneous nodular enhancement<br />
of the infundibulum after administration of gadoliniumright.<br />
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Fig. 2. Photomicrograph of lymphocytic infundibuloneurohypophysitis.<br />
Note infiltration of many lymphocytes and<br />
a few plasma cells in the pituitary stalkH & E, 400.<br />
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J Korean Neurosurg SocVolume 29June, 2000 823
<strong>림프구성</strong> 누두신경뇌하수체염:증례 <strong>보고</strong> <strong>및</strong> <strong>문헌고찰</strong><br />
Fig. 3. Seven months after the operation, the follow-up gadolinium-enhanced coronal T1-weighted MR image demonstrating disappearance<br />
of previous infundibular noduleRight, but remained loss of high signal in neurohypophysis on sagittal T1-<br />
weighted MR imageLeft.<br />
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고 찰<br />
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824<br />
J Korean Neurosurg SocVolume 29June, 2000
손영제 · 왕규창 · 최기영 · 지제근 · 조병규<br />
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결 론<br />
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References<br />
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1) Baskin DS, Townsend JJ, Wilson CB:Lymphocytic adenohypophysitis<br />
of pregnancy simulating a pituitary adenoma:A<br />
distinct pathological entity. Report of two cases. J Neurosurg<br />
56:148-153, 1982<br />
2) Chae HB, Park JY, Shong YK, Kim KJ, Kim CH, Hwun BD,<br />
et al:A case of lymphocytic infundibuloneurohypophysitis.<br />
Korean J Med 53:345-349, 1997<br />
3) Fujisawa I, Nishimura K, Asato R, Togashi K, Itoh K, Noma<br />
S, et al:Posterior lobe of the pituitary in diabetes insipidus:<br />
MR findings. J Comput Assist Tomogr 11:221-225, 1987<br />
4) Hashimoto K, Takao T, Makino S:Lymphocytic adenohypophysitis<br />
and lymphocytic infundibuloneurohypophysitis. Endocr<br />
J 44:1-10, 1997<br />
5) Imura H, Nakao K, Shimatsu A, Ogawa Y, Sando T, Fujisawa<br />
I, et al:Lymphocytic infundibuloneurohypophysitis as a cause<br />
of central diabetes insipidus. N Engl J Med 329:683-689, 1993<br />
6) Kamel N, Ilgin SD, Corapcioglu D, Dela H, Gullu S:Lymphocytic<br />
infundibuloneurohypophysitis presenting as diabetes<br />
insipidus in a man. J Endocrinol Invest 21:537-540, 1998<br />
7) Kojima H, Nojima T, Nagashima K, Ono Y, Kudo M, Ishikura<br />
H:Diabetes insipidus caused by lymphocytic infundibulo-neurohypophysitis.<br />
Arch Pathol Lab Med 113:1399-1401, 1989<br />
8) Saito T, Yoshida S, Nakao K, Takanshi R:Chronic hypernatremia<br />
associated with inflammation of the neurohypophysis.<br />
J Clin Endocrinol Metab 31:391-396, 1970<br />
9) Sato N, Sze G, Endo K:Hypophysitis:Endocrinologic and<br />
dynamic MR findings. AJNR Am J Neuroradiol 19:439-<br />
444, 1998<br />
J Korean Neurosurg SocVolume 29June, 2000 825
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