Acute Variceal Bleeding
Acute Variceal Bleeding
Acute Variceal Bleeding
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Vasoactive Drugs<br />
• Somatostatin & Analogues<br />
– Octreotide & Vapreotide<br />
– Inhibits vasodilator hormones e.g. glucagon,<br />
+/- direct vasoconstricting property<br />
• Splanchnic vasocontriction<br />
• Vasopressin & Analogues<br />
– Terlipressin<br />
– Non-specific arteriolar vasoconstriction<br />
• Splanchnic vasocontriction