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Acute Variceal Bleeding

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Management of Coagulopathy<br />

• FFP and/ or Platelets<br />

– Can be considered in patients with significant<br />

coagulopathy and/or thrombocytopenia<br />

• Recombinant Factor VIIa<br />

– No benefit in cirrhotic patients with UGIB in<br />

general<br />

– But post hoc analysis data shows reduced<br />

failure to control variceal bleeding in Child’s B,<br />

C patients<br />

Garcia-Tsao G et al. Hepatology 2009<br />

Bosch J et al. Gastroenterology 2004

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