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Acute Variceal Bleeding

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• Restrictive transfusion strategy (Tx if Hb < 7)<br />

vs Liberal transfusion strategy (Tx if Hb < 9)<br />

in 921 patients with UGIB<br />

• In subgroup analysis of 277 patients with<br />

cirrhosis<br />

– Reduced rate of re-bleeding & mortality in the<br />

restrictive transfusion group in Child’s A or B patients<br />

– No difference in Child’s C patients<br />

Vaillanueva et al. NEJM 2013

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