Prioritizing new malaria vaccine candidates for further development
Prioritizing new malaria vaccine candidates for further development
Prioritizing new malaria vaccine candidates for further development
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Global <strong>malaria</strong> <strong>vaccine</strong> pipeline<br />
Phase 1a<br />
TRANSLATIONAL PROJECTS<br />
Phase 2a<br />
Phase 1b<br />
VACCINE CANDIDATES<br />
Phase 2b Phase 3<br />
ChAd63/MVA ME-<br />
TRAP + Matrix M<br />
(Ox<strong>for</strong>d U)<br />
Ad35.CS/RTS,S-AS01<br />
(GSK/Crucell/WRAIR)<br />
PvCSP-AS01<br />
(WRAIR/GSK)<br />
Ad35.CS.01<br />
(NIAID)<br />
ChAd63/MVA<br />
ME-TRAP<br />
(Ox<strong>for</strong>d U)<br />
RTS,S-AS01<br />
(GSK)<br />
PfSPZ<br />
(Sanaria)<br />
Ad35.CS/Ad26.CS<br />
(Crucell/Seattle<br />
BioMed)<br />
ChAd63/MVA<br />
MSP 1<br />
(Ox<strong>for</strong>d U)<br />
AMA1-C1-<br />
Alhydrogel+CPG<br />
7909 (NIAID)<br />
FMP2.1-AS02A<br />
(AMA1 3D7)<br />
(USAMRMC)<br />
Polyepitope DNA<br />
EP 1300<br />
(NIAID)<br />
ChAd63/MVA<br />
(Ox<strong>for</strong>d U)<br />
ChAd63.AMA1/<br />
MVA.AMA1<br />
(Ox<strong>for</strong>d U)<br />
BSAM-2-Alhydrogel<br />
+ CPG 7909<br />
(NIAID)<br />
GMZ2<br />
(EVI)<br />
PfCelTOS FMP012<br />
(USAMRMC)<br />
ChAd63/MVA<br />
(CS; ME-TRAP)<br />
(Ox<strong>for</strong>d U)<br />
FMP2.1-AS01B<br />
(AMA1 3D7<br />
(USAMRMC)<br />
CSP, AMA1<br />
(PEV 301, 302)<br />
(Swiss TPH)<br />
MSP3 [181-276]<br />
(EVI)<br />
CSVAC<br />
(Ox<strong>for</strong>d U)<br />
PfSPZ<br />
(Sanaria)<br />
NMRC.M3V.Ad.PfCA<br />
(USAMRMC)<br />
EBA 175.R2<br />
(NIAID)<br />
ChAd63.AMA/MVA.<br />
AMA1 +Al/CPG7909<br />
(Ox<strong>for</strong>d U)<br />
PfGAP p52- / p32-<br />
(Seattle BioMed)<br />
NMRC.M3V.D/<br />
Ad.PfCA<br />
(USAMRMC)<br />
SE36<br />
(Osaka U)<br />
SR11.1<br />
(Institut Pasteur)<br />
PfSPZ-CVac<br />
(Ox<strong>for</strong>d U)<br />
Pfs25-EPA<br />
(NIAID)<br />
P. falciparum <strong>vaccine</strong>s: Pre-erythrocytic Blood-stage Transmission-blocking<br />
P. vivax <strong>vaccine</strong>s: Pre-erythrocytic Blood-stage Transmission-blocking<br />
Data source: http://www.who.int/<strong>vaccine</strong>_research/links/Rainbow/en/index.html<br />
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