Prioritizing new malaria vaccine candidates for further development
Prioritizing new malaria vaccine candidates for further development Prioritizing new malaria vaccine candidates for further development
The Malaria Vaccine Technology Roadmap circa 2006 Priorities circa 2006 • Prevent severe disease and death • P. falciparum • Children under five • Sub-Saharan Africa and other highly endemic countries • In conjunction with other malaria interventions http://www.malariavaccine.org/files/Malaria _Vaccine_TRM_Final_000.pdf 10
1 2 Reasons to update the Roadmap • “The need to update the Roadmap Vision and 2025 Strategic Goal in response to a number of changes since 2006, including changes in the strategic role of malaria vaccines and changes in malaria epidemiology and control status.” 1 • “Further reviews of the vision and strategic goals will occur at least every 5 years in light of the epidemiological and control situation at that time and progress with other tools and technologies. Changes will be made only if necessary. Should projects aimed at either of the 2 strategic vaccine goals reach major milestone performance indicators, such as proof of concept of efficacy, this will trigger a WHO-led consultative process to develop new Landmark goals for late stage development of these vaccines.” 2 http://www.who.int/vaccine_research/diseases/malaria/roadmap_update_jul12/en/index.html http://www.who.int/vaccine_research/diseases/malaria/Roadmap_update_for_second_public_c onsultation.pdf 11
- Page 1 and 2: Prioritizing New Malaria Vaccine Ca
- Page 3 and 4: Why prioritize • No need to prior
- Page 5 and 6: Global malaria vaccine pipeline Pha
- Page 7 and 8: What to prioritize • Strategic go
- Page 9: The Malaria Vaccine Technology Road
- Page 13 and 14: Updating the Malaria Vaccine Techno
- Page 15 and 16: Strategic goals, outcomes, and vacc
- Page 17 and 18: Strategic goals, outcomes, and vacc
- Page 19 and 20: Thoughts on how vaccine candidates
- Page 21 and 22: Cost Low High A commercial-sector m
- Page 23 and 24: Cost Low High A commercial-sector m
- Page 25 and 26: Sources and management of uncertain
- Page 27 and 28: Prioritizing through defining/manag
- Page 29 and 30: Summary • There is an ongoing nee
The Malaria Vaccine Technology Roadmap circa 2006<br />
Priorities circa 2006<br />
• Prevent severe disease<br />
and death<br />
• P. falciparum<br />
• Children under five<br />
• Sub-Saharan Africa and<br />
other highly endemic<br />
countries<br />
• In conjunction with other<br />
<strong>malaria</strong> interventions<br />
http://www.<strong>malaria</strong><strong>vaccine</strong>.org/files/Malaria<br />
_Vaccine_TRM_Final_000.pdf<br />
10
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