Current issues in Hereditary Angioedema (HAE) - Ipopi

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Current issues in HAE • Overview of HAE • New/ newly licensed drugs – C1 inhibitor (Berinert, Cetor, Cinryze) – Recombinant C1 inhibitor (Rhucin) – Icatibant (Firazyr) – Ecallantide (DX88; Kalbitor) • Rational use of preventatıve medıcatıon – Danazol/ stanozolol/ oxandrolone • General issues
What is HAE (Hereditary • HAE 1 or 2 .. Lack of C1 inhibitor protein angioedema) • HAE 3 ..similar symptoms but not C1 inhibitor deficiency • AAE (acquired angioedema) – Lack of C1 inhibitor developing in later life
Page 1: Current issues in Hereditary Angioe
Page 5 and 6: C1 inhibitor controls inflammation
Page 7 and 8: What have we learnt about the new
Page 9 and 10: • Berinert (C1 inhibitor) trials
Page 11 and 12: Treatment of C1 inhibitor deficienc
Page 13 and 14: Icatibant (Firazyr) • Recurrent a
Page 15 and 16: Living with hereditary angioedema:
Page 17 and 18: L’s story: 25 year old with HAE
Page 19 and 20: L’s story •15 th March 2010- 2
Page 21 and 22: Treatment of C1 inhibitor deficienc
Page 23 and 24: Self administration C1 ınhıbıtor
Page 25 and 26: C1 inhibitor controls local Healthy
Page 27: Rational use of steroids….
Page 30 and 31: Mr B 15 years • Unwilling to trai
Page 32 and 33: Mrs B 42 years • Danazol 100 mg a
Page 34 and 35: Need to control acute attacks
Page 36 and 37: What does everyone want • Patient
Page 38: Recent initiatives • World consen

Current issues in Hereditary Angioedema (HAE) - Ipopi

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