Mondobiotech Holding AG Company presentation
Mondobiotech Holding AG Company presentation
Mondobiotech Holding AG Company presentation
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The Model<br />
• Knowledge from literature is interpreted as a<br />
network of concepts (nodes) and relations among<br />
them (links)<br />
• Concepts are well-defined and relevant biological<br />
or medical entities such as peptides, proteins,<br />
receptors, physiological pathways, biological<br />
processes, symptoms and diseases<br />
• Exploiting the techniques of the mathematical<br />
theory of networks, data-driven analyses can be<br />
performed against the knowledge network to<br />
search for emergent patterns, highlighting or<br />
detecting unnoticed and indirect relations among<br />
concepts<br />
• Specifically, we focus on matching the information<br />
on peptides and biological processes with the<br />
patho-physiological signs and symptoms of the rare<br />
diseases<br />
• We use a different approach, defining links<br />
between concepts as words co-occurrences within<br />
sentences in literature<br />
• In our model each link is given a numeric measure<br />
of relevance (weight), depending on the syntactic<br />
structure of the sentence it is extracted from<br />
• As more and more papers are analyzed, links are<br />
added or their weight increased<br />
Structured bio knowledge-based cloud<br />
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