ULTIMATE COMPUTING - Quantum Consciousness Studies
ULTIMATE COMPUTING - Quantum Consciousness Studies
ULTIMATE COMPUTING - Quantum Consciousness Studies
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80 Cytoskeleton/Cytocomputer<br />
a,<br />
5 Cytoskeleton/Cytocomputer<br />
Living organisms are collective assemblies of cells which contain collective<br />
assemblies of organized material called protoplasm. In turn, protoplasm consists<br />
of membranes, organelles, nuclei and the bulk interior medium of living cells:<br />
cytoplasm. Dynamic rearrangements of cytoplasm within eukaryotic cells account<br />
for their changing shape, repositioning of internal organelles, and in many cases,<br />
movement from one place to another. We now know that the cytoskeleton, a<br />
dynamic network of filamentous proteins, is responsible for cytoplasmic<br />
organization (Figures 5.1 thru 5.3).<br />
5.1 The Nature of Cytoplasm<br />
The nature of cytoplasm has been scientifically studied for at least a century<br />
and a half. That history was described by Beth Burnside (1974) in a landmark<br />
meeting devoted to the cytoskeleton at the New York Academy of Sciences.<br />
An early French observer of cellular material, Felix Du Jardin proposed in<br />
1835 that all cells were composed of a motile material called “sarcode” that had<br />
both structural and contractile properties. In 1861, Austrian E. Brucke linked the<br />
mechanical and physiological properties of cells to a fundamental organization or<br />
architecture of cytoplasm as distinguished from purely chemical or physical<br />
properties. Early Dutch microscopist van Leeuwenhoek observed that red blood<br />
cells became deformed passing through capillaries Hand then sprang back into<br />
shape, demonstrating the elasticity of cytoplasm. The variety of elaborate forms<br />
that cells assume and maintain also require some cytoplasmic rigidity, properties<br />
which led nineteenth century biologists to conclude that cytoplasm is not merely a<br />
liquid nor an emulsion nor an aqueous suspension of life bearing granules. Rather,<br />
cytoplasmic architecture and contractility could be explained by the proposal of a<br />
mesh-like “reticular” or “fibrous” substructure whose interstices were filled with<br />
fluid. To some early biologists, the structure of cytoplasm therefore consisted of a<br />
continuous reticular network of delicate fibrils extending through the cell<br />
(reticular theory). Others claimed that the fibrils forming the cytoplasmic<br />
substratum were unbranched and discontinuous (fibrillar theory). Both of these<br />
theories were initially supported, but later deflated, by microscope preparation<br />
techniques of fixation and staining which arose between 1870 and 1890. Fibrillar<br />
and reticular frameworks appeared everywhere in many types of fixed cells,<br />
particularly in muscle, nerve, cartilage and epithelial cells.