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ULTIMATE COMPUTING - Quantum Consciousness Studies

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Viruses/Ambiguous Life Forms 185<br />

Figure 9.1: Phage virus landing and injecting genetic material into host cell. The<br />

cylindrical collar undergoes a collective conformational contraction associated<br />

with the injection. By Paul Jablonka.<br />

Generally, viruses enter cells and pirate their genetic machinery to cause<br />

virus multiplication; they then escape to begin another cycle. Some viruses<br />

quietly and harmlessly reside within host cells for extremely long periods of time<br />

whereas the sojourn of other viruses involves the total commandeering of cell<br />

machinery and can have extremely damaging consequences for the host. Virus<br />

induced human diseases range from trivial common colds and influenza to<br />

chicken pox, measles, hepatitis, polio, and deadly diseases such as smallpox,<br />

rabies, yellow fever, cancer, and acquired immunodeficiency syndrome<br />

(“AIDS”). Some viral diseases such as smallpox have been controlled by modern<br />

medicine but others such as AIDS remain significant threats to human health.<br />

Once assembled inside a host cell, viruses can escape in several ways. One<br />

route involves causing the death and disintegration of the host cell, allowing the<br />

newly formed viruses to spill out and carry their infection elsewhere. Viruses<br />

which are covered by lipid membranes can also escape by “budding” or reverse<br />

endocytosis (“pinocytosis”), a mechanism similar to secretion or extrusion of<br />

neurotransmitter vesicles from synaptic boutons.<br />

An important subclass of viruses are retroviruses which contain RNA without<br />

DNA. When arriving within a host cell, the retrovirus brings an enzyme known<br />

as reverse transcriptase which converts the virus single stranded RNA into a<br />

double stranded DNA copy. This allows the virus to commandeer the host cell<br />

genetic machinery. Among the human retroviruses is HTLV-III (or “HIV”),<br />

carrier of AIDS.

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