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ULTIMATE COMPUTING - Quantum Consciousness Studies

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110 Cytoskeleton/Cytocomputer<br />

of biomolecules which are not actively transported was explained on the basis of<br />

cytomatrix barriers and channels. However, Gershon, Porter and Trus (1985)<br />

studied molecular diffusion through cytoplasm and came to a different<br />

conclusion. They found that the cytoskeleton/cytomatrix/MTL comprised from 16<br />

to 21 percent of cytoplasmic volume, and that the cytoskeleton/cytomatrix/MTL<br />

surface area was from 69,000 to 91,000 square microns per cell (69 to 91 billion<br />

square nanometers). Their data has been interpreted to suggest that the cell “solid<br />

state” (cytoskeleton/cytomatrix/MTL) is not a barrier to diffusion since the<br />

aqueous phase occupies 4/5 of cell volume. They conclude that proteins and other<br />

molecules are dynamically bound to the solid state, accounting for the slow<br />

diffusion (Figure 5.21).<br />

Biologist James Clegg (1981) has discussed how the binding of “soluble”<br />

enzymes to the solid state could account for the efficiency of various enzymatic<br />

processes. A sequence of enzymes in a complex biochemical pathway is much<br />

more efficient if physically arranged so that a cascade of reaction products occurs.<br />

If the product of one enzyme is the precursor for its neighbor enzyme, transfer<br />

time is minimized and the reactions are usefully facilitated. This also allows the<br />

possibility of dynamic regulation of these enzymes by the solid state structures.<br />

Clegg has also accrued evidence regarding the role of water within cytoplasm,<br />

particularly surrounding solid state structures. Using neutron diffraction and other<br />

techniques, Clegg has found that water adjacent to the cytomatrix is “ordered,”<br />

that is aligned with polar bonds on the protein surfaces. Thus a layer of ordered<br />

water extends at least 3 nanometers from the billions of square nanometers of<br />

solid state surface area within each cell. This ordered water may be coupled by<br />

dipole oscillation to dynamics of the solid state, inhibit the thermal dissipation of<br />

protein oscillation energy from within the solid state, and shield calcium and other<br />

ions from random solid state interactions. Clegg also suggests that additional<br />

layers of slightly less ordered water (“vicinal water”) extending further from the<br />

solid state would limit true “aqueous” water within cells to narrow cellular<br />

“sewage channels.”

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