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IonWorks Quattro Assay - Molecular Devices

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Nav1.7 Mutations Cause Pain in Human<br />

Diseases<br />

Point Mutations<br />

Over-Active Channels<br />

S241T<br />

N395K<br />

I848T<br />

L858H,F<br />

A863P<br />

F1449V<br />

Primary Erythermalgia<br />

Paroxysmal Extreme<br />

Pain Disorder<br />

Nerve Hyperactivity<br />

Yang et al, 2004; Cummins et al, 2004 and others

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