Annual Activities Report 2011 - INCT-Inofar - UFRJ

Annual Report 2011 | INCT-INOFAR
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Events
5 th ENIFARMED
From August 29 to August 31, 2011, in the city of Sao Paulo, the 5 th National Meeting of Innovation in
Pharmaceuticals and Medications – ENIFarMed debated the theme “The Health Industrial Complex:
Strategic in access to medications”.
A consolidated forum to stimulate the direct interaction of P, D&I professionals as well as of companies
in the chain of production and of ICTs (Science and Technology Institutes) and Universities, the
event aims to establish a common agenda among government and regulatory agencies in Brazil for the
advancement of technological innovation in pharmaceuticals and medications in Brazil.
Technical Acknowledgement Award
INCT-INOFAR received the Technical Acknowledgement Award in the 5 th ENIFarMed for the panel
“Total synthesis of atorvastatin calcium”. Authored by Dr. Adriano Siqueira Vieira and Prof. Luiz Carlos
Dias, INCT-INOFAR researchers connected to the Institute of Chemistry of UNICAMP, the work was
one of 6 projects selected for oral presentation at the event. Among the selection criteria were adequacy
of project to a market focus; conceptual and practical basis, and social relevance of the theme.
The award winning paper summarizes the efforts
of INCT-INOFAR in the discovery of a new
synthetic route for atorvastatin, the active principle
of Lipitor®/ Pfizer, the worldwide most sold
medication, which had its patent expire in Brazil
on December 2010.
The synthetic methodology developed by INCT-
INOFAR represents an innovative way to obtain
the generic Lipitor®. By reducing stages in the
synthetic route, the UNICAMP researchers have
made it more efficient and cheaper when compared
to the original route described in the Pfizer patent.
There is also the advantage of presenting some new
intermediates, with simple synthetic access.
Adriano Siqueira and Luiz Carlos Dias
(UNICAMP)