Annual Activities Report 2011 - INCT-Inofar - UFRJ

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Annual Report 2011 | INCT-INOFAR 28 INCT-INOFAR has the support, albeit informal, of pharmaceutical companies like Cristalia Chemical Pharmaceutical Products Ltd., Royal Institute, In Vitro Cells Toxicological Research S.A. and Ciallyx Laboratories & Consultants.
Annual Report 2011 | INCT-INOFAR 29 Associated Companies Presentation In Vitro Cells www.invitrocells.com.br In Vitro Cells – Toxicological Research S.A. is a technology based company located at Biominas Foundation (Belo Horizonte, MG). Its founders are professors of the Federal University of Minas Gerais (UFMG) in the fields of Toxicology and Biochemistry. The company is an INCT-INOFAR partner to conduct in vitro bioassays to test the safety and efficacy of new pharmaceutical candidates developed by the Institute. Cristalia Laboratories Chemical and Pharmaceutical Products www.2cristalia.com.br Cristalia is a pharmaceutical company associated with INCT-INOFAR, capable of supporting the stages of pharmacotechnical developing of new prototype compounds that reach this advanced stage of the chain of innovation in pharmaceuticals and medications. Under confidentiality and non-disclosure terms, Cristalia will benefit, if it wishes, from information on the current projects, by expressing an interest in absorbing the technology developed at INCT-INOFAR. So that the technology may be transferred, the Innovation Agency of UFRJ and its peer at another INCT-INOFAR research institution will negotiate directly with the interested parties, including financial backers. Royal Institute (Instituto Royal) www.institutoroyal.org.br Toxicology is a very delicate stage that might absolve or condemn forever a pharmaceutical candidate prototype. INCT-INOFAR prioritizes the studies of cytotoxicity, mutatoxicity, and genotoxicity, as well as acute toxicology, with the molecules that have proven attractive in terms of pharmacological activities as early as possible in the chain of pharmaceutical innovation. To ensure that all the preclinical toxicology stages are accredited in good laboratory practices (BPL/GLP), INCT-INOFAR has a partnership with the Royal Institute, which is a result of the merger of two toxicology laboratories housed in two different universities. The Genotox-Royal Institute, located at UFRGS, is responsible for the genetic toxicity studies, while Unitox-Royal, located at the University of Santo Amaro (UNISA-SP) is responsible for animal toxicity tests. Ciallyx Laboratories & Consultants www.ciallyx.com.br Ciallyx Laboratories & Consultants is a company housed at CIETEC (Incubator Center for Technological Companies) that carries out efficacy studies (concept tests) and safety studies (studies and toxicological assays) for new molecules, medications, and formulations. Ciallyx achieves results by following national and international protocols under strict quality parameters, guided by the international guidelines of the Good Laboratory Practices – GLP. The company is an INCT-INOFAR partner to conduct in vivo bioassays to evaluate the safety and efficacy of new pharmaceutical candidates developed by the Institute.
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