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Annual Activities Report 2011 - INCT-Inofar - UFRJ

Annual Activities Report 2011 - INCT-Inofar - UFRJ

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<strong>Annual</strong> <strong>Report</strong> <strong>2011</strong> | <strong>INCT</strong>-INOFAR<br />

17<br />

Presentation<br />

25] Discovery of new antitumor pharmaceutical<br />

candidates analog to combrestatin A4.<br />

Prof. Lidia Moreira Lima (<strong>UFRJ</strong>) – CV-Lattes<br />

26] Development of new anti-inflammatory and<br />

analgesic pharmaceutical candidates<br />

from safrole.<br />

Prof. Lidia Moreira Lima (<strong>UFRJ</strong>) – CV-Lattes<br />

27] Study for the identification of new<br />

sulfonamide compounds effective in the<br />

control of pulmonary inflammation caused<br />

by silica in mice.<br />

Prof. Patricia Machado Rodrigues e<br />

Silva Martins (FIOCRUZ-RJ) – CV-Lattes<br />

28] Implementation and validation of<br />

pre-clinical trial model for the evaluation<br />

of the teratogenic effect of bioactive<br />

substances: evaluation of the LASSBio 468<br />

and LASSBio 596 prototypes.<br />

Prof. Aloa Machado de Souza – CV-Lattes<br />

Multidisciplinary<br />

Research Network<br />

The pharmaceutical innovation process has clear interdisciplinary and multidisciplinary<br />

characteristics that demand competences in distinct areas of health sciences. <strong>INCT</strong>-<br />

INOFAR is aware of this, and therefore coordinates a network of research groups that<br />

excel scientifically and academically in different areas, and that have a history of previous<br />

results that makes them qualified to carry out successfully the several stages of the process of<br />

rational invention of new pharmaceuticals.<br />

<strong>INCT</strong>-INOFAR has a multidisciplinary staff of experts in several areas such as Medicinal<br />

Chemistry, Pharmacology, Organic Chemistry, Toxicology, Organic Synthesis, Biochemistry,<br />

Computational Chemistry, Spectroscopy, and Natural Products Chemistry, among others.

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