Annual Activities Report 2011 - INCT-Inofar - UFRJ
Annual Activities Report 2011 - INCT-Inofar - UFRJ
Annual Activities Report 2011 - INCT-Inofar - UFRJ
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<strong>Annual</strong> <strong>Report</strong> <strong>2011</strong> | <strong>INCT</strong>-INOFAR<br />
16<br />
Presentation<br />
13.] Evaluation of the leishmanicide activity<br />
of a series of semicarbazone and<br />
hydrazine-N-acylhydrazone derivates.<br />
Prof. Magna Suzana Alexandre<br />
Moreira (UFAL) – CV-Lattes<br />
EARLY STAGES<br />
14] Theoretical investigation of the action<br />
mechanism of dialkylphosphorylidrazones<br />
as inhibitors of the ribose 5-phosphate<br />
isomerase enzyme of the Trypanosoma<br />
cruzi and plasmodium falciparum.<br />
Prof. Carlos Mauricio R. de<br />
Sant’Anna (UFRRJ) – CV-Lattes<br />
15] Triage of new inhibitors of the replication<br />
of the human immunodeficiency virus type<br />
1 (HIV-1) from LASSBio chemical library.<br />
Prof. Luciana Jesus da Costa (<strong>UFRJ</strong>) – CV-Lattes<br />
16] Evaluation of antitumor activity of new<br />
molecules structurally planned from<br />
imatinib prototype.<br />
Prof. Patricia Dias Fernandes (<strong>UFRJ</strong>) – CV-Lattes<br />
17] Prospection of opportunities in new<br />
generics and innovative generics.<br />
P rof. Adelaide Mª de Souza Antunes (<strong>UFRJ</strong>) – CV-Lattes<br />
NEW APPROVED SUBMISSIONS<br />
18] Pharmacological and toxicological evaluation<br />
of new pharmaceutical candidates for the<br />
prevention and treatment of myocardiopathy<br />
and neuropathy caused by diabetes mellitus.<br />
Prof. Gisele Zapata Sudo (<strong>UFRJ</strong>) – CV-Lattes<br />
19] Planning of structural changes for the<br />
optimization of the affinity of the IKK2,<br />
LASSBio-1524 enzyme selective inhibitor.<br />
Prof. Laurent Emmanuel Dardenne (LNCC) – CV-Lattes<br />
20] New 5-aril-2-furfuril-N-acylhydrazone<br />
derivates functionalized with Power<br />
anti-inflammatory and analgesic activity:<br />
LASSBio-1609 and LASSBio-1636.<br />
Prof. Carlos Alberto Manssour Fraga<br />
(<strong>UFRJ</strong>) – CV-Lattes<br />
21] Technological prospection of new<br />
generics in Brazil.<br />
Prof. Adelaide Maria de Souza Antunes<br />
(<strong>UFRJ</strong>) – CV-Lattes<br />
22] Synthesis and theoretical study of the action<br />
mechanism of new dialkylphosphorylhydrazones<br />
as inhibitors of the ribose 5-phosphate<br />
isomerase enzyme.<br />
Prof. Carlos Mauricio R. de Sant’Anna<br />
(UFRRJ) – CV-Lattes<br />
23] Impact of nanoparticle therapy on the<br />
thymuline gene in chronic allergic<br />
asthma model.<br />
Prof. Patricia Rieken Macedo<br />
Rocco (<strong>UFRJ</strong>) – CV-Lattes<br />
24] Development of new antiarthritis<br />
pharmaceutical candidates,<br />
MAPK p-38 modulators.<br />
Prof. Lidia Moreira Lima (<strong>UFRJ</strong>) – CV-Lattes