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Annual Activities Report 2011 - INCT-Inofar - UFRJ

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<strong>Annual</strong> <strong>Report</strong> <strong>2011</strong> | <strong>INCT</strong>-INOFAR<br />

16<br />

Presentation<br />

13.] Evaluation of the leishmanicide activity<br />

of a series of semicarbazone and<br />

hydrazine-N-acylhydrazone derivates.<br />

Prof. Magna Suzana Alexandre<br />

Moreira (UFAL) – CV-Lattes<br />

EARLY STAGES<br />

14] Theoretical investigation of the action<br />

mechanism of dialkylphosphorylidrazones<br />

as inhibitors of the ribose 5-phosphate<br />

isomerase enzyme of the Trypanosoma<br />

cruzi and plasmodium falciparum.<br />

Prof. Carlos Mauricio R. de<br />

Sant’Anna (UFRRJ) – CV-Lattes<br />

15] Triage of new inhibitors of the replication<br />

of the human immunodeficiency virus type<br />

1 (HIV-1) from LASSBio chemical library.<br />

Prof. Luciana Jesus da Costa (<strong>UFRJ</strong>) – CV-Lattes<br />

16] Evaluation of antitumor activity of new<br />

molecules structurally planned from<br />

imatinib prototype.<br />

Prof. Patricia Dias Fernandes (<strong>UFRJ</strong>) – CV-Lattes<br />

17] Prospection of opportunities in new<br />

generics and innovative generics.<br />

P rof. Adelaide Mª de Souza Antunes (<strong>UFRJ</strong>) – CV-Lattes<br />

NEW APPROVED SUBMISSIONS<br />

18] Pharmacological and toxicological evaluation<br />

of new pharmaceutical candidates for the<br />

prevention and treatment of myocardiopathy<br />

and neuropathy caused by diabetes mellitus.<br />

Prof. Gisele Zapata Sudo (<strong>UFRJ</strong>) – CV-Lattes<br />

19] Planning of structural changes for the<br />

optimization of the affinity of the IKK2,<br />

LASSBio-1524 enzyme selective inhibitor.<br />

Prof. Laurent Emmanuel Dardenne (LNCC) – CV-Lattes<br />

20] New 5-aril-2-furfuril-N-acylhydrazone<br />

derivates functionalized with Power<br />

anti-inflammatory and analgesic activity:<br />

LASSBio-1609 and LASSBio-1636.<br />

Prof. Carlos Alberto Manssour Fraga<br />

(<strong>UFRJ</strong>) – CV-Lattes<br />

21] Technological prospection of new<br />

generics in Brazil.<br />

Prof. Adelaide Maria de Souza Antunes<br />

(<strong>UFRJ</strong>) – CV-Lattes<br />

22] Synthesis and theoretical study of the action<br />

mechanism of new dialkylphosphorylhydrazones<br />

as inhibitors of the ribose 5-phosphate<br />

isomerase enzyme.<br />

Prof. Carlos Mauricio R. de Sant’Anna<br />

(UFRRJ) – CV-Lattes<br />

23] Impact of nanoparticle therapy on the<br />

thymuline gene in chronic allergic<br />

asthma model.<br />

Prof. Patricia Rieken Macedo<br />

Rocco (<strong>UFRJ</strong>) – CV-Lattes<br />

24] Development of new antiarthritis<br />

pharmaceutical candidates,<br />

MAPK p-38 modulators.<br />

Prof. Lidia Moreira Lima (<strong>UFRJ</strong>) – CV-Lattes

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