Annual Activities Report 2011 - INCT-Inofar - UFRJ
Annual Activities Report 2011 - INCT-Inofar - UFRJ
Annual Activities Report 2011 - INCT-Inofar - UFRJ
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<strong>Annual</strong> <strong>Report</strong> <strong>2011</strong> | <strong>INCT</strong>-INOFAR<br />
15<br />
Presentation<br />
Current <strong>INCT</strong>-INOFAR<br />
Subprojects<br />
INCREMENTAL INNOVATION<br />
1] Sunitinib synthesis.<br />
Prof. Eliezer J. Barreiro (<strong>UFRJ</strong>) – CV Lattes<br />
Prof. Angelo da Cunha Pinto (<strong>UFRJ</strong>) – CV Lattes<br />
Profa. Bárbara Vasconcelos (<strong>UFRJ</strong>) – CV Lattes<br />
2] Fluoxetin synthesis.<br />
Prof. Eliezer J. Barreiro (<strong>UFRJ</strong>) – CV Lattes<br />
Prof. Luiz Carlos Dias (UNICAMP) – CV Lattes<br />
Dr. Adriano V. Siqueira (UNICAMP) – CV Lattes<br />
3] Atorvastatin synthesis (patent).<br />
Prof. Eliezer J. Barreiro (<strong>UFRJ</strong>) – CV Lattes<br />
Prof. Luiz Carlos Dias (UNICAMP) – CV Lattes<br />
Dr. Adriano V. Siqueira (UNICAMP) – CV Lattes<br />
RADICAL INNOVATION<br />
ADVANCED STAGE<br />
4] Development of new antiasthma<br />
pharmaceutical prototypes (LASSBio-596).<br />
P rof. Patricia Rieken Macedo Rocco (<strong>UFRJ</strong>) – CV-Lattes<br />
Prof. Lidia Moreira Lima (<strong>UFRJ</strong>) – CV-Lattes<br />
5] Study of N-phenylpiperazine derivates<br />
functionalized as prototypes for the<br />
development of new atypical antipsychotics.<br />
Prof. Stela Maris Kuze Rates (UFRGS) – CV-Lattes<br />
P rof. Carlos Alberto Manssour Fraga (<strong>UFRJ</strong>) – CV-Lattes<br />
SEMI-ADVANCED STAGE<br />
6] Study of the potential anti-inflammatory effect of<br />
compound LASSBio 897, in models of silicosis and asthma.<br />
Prof. Patricia Machado Rodrigues e Silva<br />
(FIOCRUZ – RJ) – CV-Lattes<br />
Prof. Marco Aurelio Martins (FIOCRUZ – RJ) – CV-Lattes<br />
INTERMEDIATE STAGES<br />
7] Semicarbazone benzaldehyde (BS).<br />
Prof. Heloisa de Oliveira Beraldo (UFMG) – CV-Lattes<br />
8] Therapeutic potential of new vasodilator (LASSBio 1289)<br />
in arterial and pulmonary hypertension.<br />
Prof. Gisele Zapata Sudo (<strong>UFRJ</strong>) – CV-Lattes<br />
9] Pharmacological evaluation of new neuroactive<br />
derivates of Zolpidem<br />
Prof. Roberto Takashi Sudo (<strong>UFRJ</strong>) – CV-Lattes<br />
10] “In silico” prediction and “in vitro” production by<br />
bioconversion of human metabolites of pharmaceutical<br />
prototype candidates.<br />
Prof. Valeria de Oliveira (UFG) – CV-Lattes<br />
11] Planning, synthesis, and pharmacological evaluation of<br />
vectorized and self-organized neuroactive pharmaceutical.<br />
Prof. Ricardo Menegatti (UFG) – CV-Lattes<br />
12] Planning, synthesis, structural characterization and<br />
pharmacological evaluation of new candidates for antiinflammatory<br />
and neuroactive pharmaceuticals.<br />
Prof. Claudio Viegas Junior (UNIFAL) – CV-Lattes
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