Soil Generic Assessment Criteria for Human Health Risk ... - ESdat

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1,2,4-Trimethylbenzene 95-63-6 Assessor A: Gareth Wills Assessor B: Mat Rouge Final Review: Panel/SF
Date 08/04/2009 Date 15/04/2009 Date 28/08/2009
MDI
Recommended
MDIoral
Units
24 ug day-1
Justification: Only literature value obtained. Conservative, based upon maximum recorded concentration in tap water (US National Tap
Water Quality Database). Converted assuming 2L/d consumed.
Organisation Date Media Value Units Description Reference Web link
Other - National Tap Water
tap water
Max concentration in
National Tap Water Quality Database
Quality Database
tap water 12ppb
24 ug/d
(assuming
2litres of
water/d)
value taken from highest recorded concentration in tap
water, US. Converted to daily intake assuming 2 litres of
water consumed per day.
http://www.ewg.org/tapwater/contaminants/contaminant.phpcontamcode=2418
MDI Recommended MDIinh Units
86 ug day-1
Justification: only literature value obtained (TOXNET)
Organisation Date Media Value Units Description Reference Web link
Toxicological Data Network
(TOXNET)
1985 Ambient Air 86 ug day-1
The average daily dose of 1,2,4-trimethylbenzene from
breathing air in The Netherlands was estimated as 86
ug/day based on average ambient air concentrations of
0.50-1.15 ppb (conversion not detailed within Toxnet -
but is assumed to be approximately 1.15e-9 x 1 atm x
120.19 g.mol-1 x 15 m3.d-1 x 1e6 ug.g-1 / ( 8.206e-5
atm.m3.mol-1.K-1 x 288 K)
Guicherit R, Schulting FL; Sci Total Environ 43: 193-219 (1985)
http://toxnet.nlm.nih.gov/
(Page 1 of 1) (EIC proforma 1,2,4-trimethylbenzene.xls 28/08/2009)