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N Dixon,
1,1-dichloroethane CAS 75-34-3 Assessor A: J Thornton, Golder Associates Assessor B: WorleyParsons Final review: Panel/SF
Date 16/04/2009 Date 06/05/2009 Date 28/08/2009
MDI Recommended MDIoral Units
ug day-1
20
Justification: ata from WHO, only data from SR2 listed sources
Organisation Date Media Value Units Description Reference Web link
Pesticides Safety Directorate 01/04/2009 No data www.pesticides.gov.uk
Committee on Carcinogenicity of
Chemicals in Food, Consumer
Products and the Environment
(COC)
01/04/2009 No data www.advisorybodies.doh.go
v.uk/coc/index.htm
Committee on Mutagenicity of
Chemicals in Food, Consumer
Products and the Environment
(COM)
WHO Guidelines for Drinking
Water Quality
01/04/2009 No data www.advisorybodies.doh.go
v.uk/com/
14/04/2009 Drinking Water 20 ug/day Report on DCA
(2003) using data
presented, this
assumes intake of
drinking water at
10ug/day (US data)
and 2 L per day
http://www.who.int/wat www.who.int/water_sanitat
er_sanitation_health/dwq ion_health/dwq/guidelines/
/1,1-Dichloroethane.pdf en
Howard et al 15/04/2009 Drinking water 0 - 1.2 ug/day Data presented in
Howard et al, 1990.
Howard et al 1990,
Handbook of Env
States that exposure Fate and Exposure
via food is probably
insignificant.
data for Organic
chemicals , Volume
2, p 146
MDI Recommended MDIinh Units
ug day-1
4
Justification: Two sources quote a value of 4 ug.day -1 (both
WHO). US study cites a range of 1.0 to 5.4 ug.day -1 (ECB)
Organisation Date Media Value Units Description Reference Web link
European Chemicals Bureau (ECB) 14/04/2009 ambient air 1-5.4 ug.day -1 0.05-0.27 ug.m 3 IUCLD dataset http://ecb.jrc.it/
from USA data
WHO Guidelines for Drinking
Water Quality
06/04/2009 ambient air 4.4 ug.day -1 Median value of 0.22
WHO Air Quality Guidelines for
Europe
Toxicological Data Network
(TOXNET)
ug/m 3 from study in
USA
14/04/2009 ambient air 4 ug.day -1 Report on DCA http://www.who.int/wat
er_sanitation_health/dwq
(2003), exposure is
/1,1-Dichloroethane.pdf
greatest through
ambient air. Mediun
value.
06/04/2009 Ambient air 4.94 ug.day -1 Medium value of
0.061 ppb recorded
in 455 US samples
from urban and
suburban air.
Converted to 4.94
ug.day-1
(0.0409*0.061*MW)
.
www.who.int/water_sanitat
ion_health/dwq/guidelines/
en
www.euro.who.int/air/activi
ties/20050222_2
Brodzinsky R, Singh http://toxnet.nlm.nih.gov/
HB; Volatile
Organic Chem in
the Atmos, An
Assess of Available
Data; Menlo Park,
CA: Atmos Sci
Centr, SRI Internatl
68-02-3452 pp. 198
(1982)
Other 15/04/2009 Ambient air 5 ug.day -1 Data presented in
Howard et al, 1990
assuming
background of 61
ppt
Howard et al 1990,
Handbook of Env
Fate and Exposure
data for Organic
chemicals , Volume
2, p 146
(Page 1 of 1) (EIC proforma 1,1-dichloroethane.xls 28/08/2009)