Soil Generic Assessment Criteria for Human Health Risk ... - ESdat

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1, 1-Dichloroethane CAS Number: 75-34-3 Assessor A: J Thornton, Golder Assessor B: N Dixon, Worley Parsons Final review: Panel/SF
Associates
Date 15/04/2009 Date 06/05/2009 Date 28/08/2009
Oral
Dermal
Inhalation
Combine Oral and Inhalation TDIs
Justification
Apply TDIoral to exposure routes
Apply IDoral to exposure routes
Apply TDIinh to exposure routes
Apply IDinh to exposure routes
Y Y Y
- - -
N N N
- - -
-
Insufficient evaluation to determine with respect to a human
carcinogen - TDIoral applied to oral, dermal and inhalation routes
Insufficient data available to with sufficient details to derive
inhalation HCV
TDI oral Recommended TDIoral Units
200 ug.kg-1.d-1
Justification
PPRTV value as only data with sufficient details to derive HCV
Organisation Web Link Last Updated Date Web Checked Health criteria type Value Initial Units CLEA units ug.kg-1.d-1 Confidence rating Basis Value Units
US EPA Provisional
Peer Reviewed
Toxicity Values
(PPRTV)
http://rais.ornl.gov/tox/un
authorized.shtml
27/09/2006 28/07/2009 Chronic oral
reference dose
0.2 mg.kg day-1 200 Low NOAEL 1000 mg.kg day-1
administered 5
days/week adjusted
to 714.3 mg.kg day-1
for continuous
exposure
mg.kg day-1
USEPA-Regional
Screening Level (RSL)
http://www.epa.gov/r
egion09/superfund/pr
g/index.html
01/04/2009 05/06/2009 Reference dose 0.2 mg.kg day-1 200 Unknown Unknown Unknown Unknown
Risk Assessment
Information System
http://rais.ornl.gov/h
omepage/rap_tool.sht
ml
13/02/1998 05/06/2009 Chronic oral
reference dose
0.1 mg.kg day-1 100 Unknown NOAEL 115 mg.kg day-1
Texas Commission on
Environmental
Quality
http://www.tceq.stat
e.tx.us/remediation/rr
r.htm
01/03/2006 05/06/2009 Oral reference dose 0.1 mg.kg day-1 100 Unknown Unknown Unknown Unknown
(Page 1 of 4) (EIC proforma 1,1-dichloroethane.xls 28/08/2009)