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Soil Generic Assessment Criteria for Human Health Risk ... - ESdat

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1,1,2 trichloroethane CAS 79-00-5 Assessor A:<br />

Jeff Thorton<br />

Melinda Evans (Firth<br />

Assessor B:<br />

(Golder Assoc.)<br />

Consultants)<br />

Final review:<br />

Panel/SF<br />

Date 15/04/2009 Date 29/04/2009 Date 25/08/2009<br />

MDI<br />

Recommended<br />

MDIinh<br />

Units<br />

Justification: European study (RIVM) and Howard et al quote a value of 1 ug/ day. The higher range<br />

of 1.1 to 5.5 ug/day is based on old US data.<br />

1 ug day-1<br />

Value<br />

Organisation Media Value Units Description Reference Web link<br />

Dutch National Institute <strong>for</strong><br />

Public <strong>Health</strong> and the<br />

15-Apr-09 Air 1 ug day-1 Air study in Germany Janssen et al. 1998. Maximum Permissible <strong>Risk</strong> Levels<br />

1986-1987, assuming <strong>for</strong> <strong>Human</strong> Intake of <strong>Soil</strong> Contaminants: Fourth Series<br />

www.rivm.nl/en/<br />

Environment (RIVM) Maximum<br />

Permissable <strong>Risk</strong> (MPR) Levels<br />

adult inhales 20<br />

m3/day (0.05 m3)<br />

of Compounds. RIVM Report No. 711701004. March<br />

1998, Page 79<br />

US Agency <strong>for</strong> Toxic Substances<br />

and Disease Registry (ATSDR)<br />

Toxicological Profiles and<br />

Minimal <strong>Risk</strong> Levels<br />

15-Apr-09 Air 1.1-5.5 ug.day-1 Average daily intake<br />

<strong>for</strong> 'background'<br />

exposure in US<br />

Toxicological Profile <strong>for</strong> 1,1,2-Trichloroethane.<br />

December 1989.<br />

http://www.atsdr.cdc.gov/toxprofiles/tp148-c5.pdf,<br />

page 71<br />

www.atsdr.cdc.gov/<br />

Other 15-Apr-09 Ambient air 1 ug/day US study of 930<br />

samples with a<br />

median<br />

concentration of 9.1<br />

parts per trillion<br />

Howard et al 1990, Handbook of Env Fate and Exposure<br />

data <strong>for</strong> Organic chemicals , Volume 2<br />

06/04/2009 Ambient air 0.01-0.05 ppb US Technology Transfer Network Air Toxics Web Site.<br />

Hazard Summary-Created in April 1992; Revised in<br />

January 2000. Based on ATDSR report<br />

06/04/2009 Outdoor residential<br />

air<br />

All below<br />

detection limit<br />

Detection Limit<br />

unknown<br />

Personal exposures<br />

among 50 persons<br />

and<br />

microenvironment<br />

concentrations of<br />

PM2.5, VOC, NO2<br />

and CO in Ox<strong>for</strong>d, UK<br />

in 1998-2000<br />

06/04/2009 Outdoor air 0.02 ug.m-3 Predicted maximum<br />

exposure<br />

concentration <strong>for</strong><br />

inhalation exposure<br />

to human beings<br />

Lai et al., Atmospheric Environment 38 (2004), 6399-<br />

6410<br />

Japanese Chemical Substances Control Document:<br />

1,1,2-trichloroethane<br />

http://epa.gov/ttn/a<br />

tw/hlthef/trietha.html<br />

http://www.ktl.fi/ex<br />

poplat<strong>for</strong>m/concdb_<br />

ui/index.phpOption<br />

=object&Object=683<br />

http://www.env.go.j<br />

p/en/chemi/chemic<br />

als/profile_erac/prof<br />

ile5/pf1-18.pdf<br />

Page 2 of 2 EIC pro<strong>for</strong>ma 1,1,2-trichloroethane 25/08/2009

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