Soil Generic Assessment Criteria for Human Health Risk ... - ESdat

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Jeff Thorton
Melinda Evans (Firth
1,1,2 trichloroethane CAS 79-00-5 Assessor A:
Assessor B:
Final review:
Panel/SF
(Golder Assoc.)
Consultants)
Date 15/04/2009 Date 29/04/2009 Date 25/08/2009
MDI
Recommended
MDIoral Units
Justification: Value of 0.24 μg.day-1 selected from European study (RIVM). OECD Report is based
on a 'worst case' scenario using Japanese data. The 1,1,1-TCA isomer has a TOX report with an oral
0.24 ug day-1 MDI of 0.2 ug/day which is comparable.
Value
Organisation Date Media Value Units Description Reference Web link
IPCS INCHEM 15/04/2009 Drinking water 2.60E+00 ug.day-1 Based on the highest OECD SIDS 1,1,2-trichloroethane SIDS Initial
http://inchem.org/
PEC of 1.30 x 10-3
mg/l (1.3 ug.L)
ASSUMING 2 L/day
Assessment Report, March 2000, section 4.1.3
(http://www.inchem.org/documents/sids/sids/79005.p
df)
for an adult
Dutch National Institute for
Public Health and the
Environment (RIVM) Maximum
Permissable Risk (MPR) Levels
US Agency for Toxic Substances
and Disease Registry (ATSDR)
Toxicological Profiles and
Minimal Risk Levels
Other
14/04/2009 Food and drink 0.24 ug day-1 Study from Germany
1980-1983
Janssen et al. 1998. Maximum Permissible Risk Levels
for Human Intake of Soil Contaminants: Fourth Series
of Compounds. RIVM Report No. 711701004. March
1998. Page 79.
14/04/2009 Drinking water no data - US Toxicological Profile for 1,1,2-Trichloroethane.
December 1989.
http://www.atsdr.cdc.gov/toxprofiles/tp148-c5.pdf
06/04/2009 Food and drinking
water
Rarely
encountered
06/04/2009 Drinking water 0.24 Japan: expected
quantities of the
maximum oral
exposure. Suspect
units quoted are
incorrect should be
ug.day-1.
- US Technology Transfer Network Air Toxics Web Site.
Hazard Summary-Created in April 1992; Revised in
January 2000
Japanese Chemical Substances Control Document:
1,1,2-trichloroethane
www.rivm.nl/en/
www.atsdr.cdc.gov/
http://epa.gov/ttn/a
tw/hlthef/trietha.html
http://www.env.go.j
p/en/chemi/chemic
als/profile_erac/prof
ile5/pf1-18.pdf
Page 1 of 2 EIC proforma 1,1,2-trichloroethane 25/08/2009