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TDI inhal<br />

Molybdenum CAS Number: 7439-98-7 Assessor A: Nick Struggles, Assessor B: Atkins Final review: Penl/SF<br />

AECOM<br />

Date 01/06/2009 Date 17/06/2009 Date 26/08/2009<br />

Recommended<br />

TDIinhal<br />

Units<br />

3.43 ug.kg-1.d-1<br />

Justification<br />

RIVM values chosen. If any of the HSE values were chosen it would be necessary to apply additional Uncertainty Factors which is out with the scope of this work.<br />

Organisation Web Link Last Updated Date Web Checked <strong>Health</strong> criteria type Value Initial Units CLEA units ug.kg- Confidence rating Basis Value Units UF UF description Study type Description<br />

1.d-1<br />

<strong>Health</strong> and Safety Executive (HSE) http://www.hse.gov.uk/ No data 30/06/1905 a) 5<br />

b) 10<br />

c) 10<br />

d) 20<br />

mg/m3<br />

Workplace<br />

exposure limit.<br />

This list is legally<br />

binding, as it<br />

reproduces the<br />

list of workplace<br />

exposure limits<br />

(WELs) which<br />

have been<br />

approved by the<br />

<strong>Health</strong> and Safety<br />

Commission<br />

a) Long-term exposure (8-hour TWA limit<br />

reference period) - soluble<br />

b) Long-term exposure (8-hour TWA limit<br />

reference period) - insoluble<br />

c) Short-term exposure limit (15minute<br />

reference period) - soluble<br />

d) Short-term exposure limit (15minute<br />

reference period) - insoluble<br />

WHO Guidelines <strong>for</strong> drinking water Quality<br />

http://www.who.int/water_sanitation_healt<br />

h/dwq/guidelines/en<br />

No data 01/06/2009 <strong>Human</strong> intake of<br />

airborne<br />

molybdenum is not<br />

likely to be a major<br />

exposure pathway<br />

Dutch National Institute <strong>for</strong> Public <strong>Health</strong><br />

and the Environment (RIVM) Maximum<br />

Permissible <strong>Risk</strong> (MPR) levels<br />

http://www.rivm.nl/en/ 01/03/2001 01/06/2009 TCA 12 ug.m-3 3.43 ( 12 ug.m3<br />

x 20m3/day /<br />

70kg )<br />

Low NOAEC 100 mg.m-3 1000 Factor of 100 <strong>for</strong> inter- and<br />

intraspecies extrapolation and 10 <strong>for</strong><br />

semi chronic to chronic exposure<br />

semi chronic<br />

NTP 1997 Study of inhalation of molybdenum<br />

trioxide in rats and mice, only effect on body<br />

weight was noticed at 300 mg.m-3. After 2 year<br />

inhalation exposure of 30 mg.m-3. Concluded<br />

changes are similar to other inhalation studies<br />

of particulate compounds and not caused by the<br />

molybdenum trioxide.<br />

ID oral<br />

Recommended<br />

IDoral<br />

None<br />

Units<br />

Justification<br />

Insufficient data<br />

Organisation Web Link Last Updated Date Web Checked Non threshold effects Basis <strong>Health</strong> criteria<br />

type<br />

Value Units Confidence rating<br />

Basis<br />

Study type Description<br />

ID inhal<br />

Recommended<br />

IDinhal<br />

None<br />

Units<br />

Justification<br />

Insufficient data<br />

Organisation Web Link Last Updated Date Web Checked Non threshold effects Basis <strong>Health</strong> criteria<br />

type<br />

Value Units Confidence rating<br />

Basis<br />

Study type Description<br />

Page 3 of 4 EIC pro<strong>for</strong>ma molybdenum.xls 26/08/2009

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