Soil Generic Assessment Criteria for Human Health Risk ... - ESdat
Soil Generic Assessment Criteria for Human Health Risk ... - ESdat
Soil Generic Assessment Criteria for Human Health Risk ... - ESdat
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TDIinhal<br />
www.esdat.net Esdat Environmental Database Management Software +61 2 8875 7948<br />
Barium CASNumber: 7440393 AssessorA: CherylDavies,Delta<br />
Simons<br />
AssessorB:<br />
JenniferStothert,<br />
EntecUKLtd<br />
Finalreview:<br />
Panel/SF<br />
Date 27/03/2009 Date 29/04/2009 Date 25/08/2009<br />
Recommended<br />
TDIinhal<br />
Units<br />
Justification<br />
Insufficientdatawithsufficientdetailonderivationtoderive<br />
Organisation WebLink LastUpdated DateWebChecked <strong>Health</strong>criteriatype Value InitialUnits CLEAunitsug.kg Confidencerating Basis Value Units UF UFdescription Studytype Description<br />
1.d1<br />
IPCSconciseInternationalChemical<br />
<strong>Assessment</strong>Documents(CICADs)<br />
http://inchem.org/pages/cicads.html 01/12/2001 27/03/2009 Thedeficientreportingofthe<br />
methodsandresultsoftheonly<br />
IPCSEnvironmental<strong>Health</strong><strong>Criteria</strong>(EHC)<br />
Monographs<br />
http://inchem.org/pages/ehc.html 1990 27/03/2009 Nopertinentdataregarding<br />
chronicinhalationexposureto<br />
DutchNationalInstitute<strong>for</strong>Public<strong>Health</strong><br />
andtheEnvironment(RIVM)Maximum<br />
Permissible<strong>Risk</strong>(MPR)levels<br />
http://www.rivm.nl/en/ 01/12/1992 27/03/2009 NoHCV Chronictoxicity Toxicitystudyoffreshwaterorganisms<br />
USEPAIntegrated<strong>Risk</strong>In<strong>for</strong>mationSystem<br />
(IRIS)<br />
IDoral<br />
http://epa.gov/iris/ 11/07/2005 08/04/2009 AnRfC<strong>for</strong>bariumisnot<br />
recommendedatthistime.The<br />
Recommended<br />
IDoral<br />
None<br />
Units<br />
Justification<br />
Insufficientdata<br />
Organisation WebLink LastUpdated DateWebChecked Nonthresholdeffects Basis <strong>Health</strong>criteria<br />
type<br />
InternationalAgency<strong>for</strong>Researchon http://inchem.org/pages/iarc.html 22/08/1997 29/04/2009 Dataonly<strong>for</strong>D&CREDNo.9(CI<br />
Cancer(IARC)<br />
PigmentRed53:1)abarium<br />
salt.D&CRedNo.9isnot<br />
classifiableastoits<br />
carcinogenicitytohumans<br />
(Group3)<br />
IPCSconciseInternationalChemical<br />
<strong>Assessment</strong>Documents(CICADs)<br />
http://inchem.org/pages/cicads.html 2001 29/04/2009 Thereisalimitedamountof<br />
in<strong>for</strong>mationavailableonthe<br />
genotoxicityofbarium<br />
compounds.Noinvivostudies<br />
havebeenconducted.Mostin<br />
vitrostudieshavefoundthat<br />
bariumchlorideandbarium<br />
nitratedidnotinducegene<br />
mutationsinbacterialassays<br />
withorwithoutmetabolic<br />
activation.<br />
Value Units Confidencerating Basis Studytype Description<br />
IPCSEnvironmental<strong>Health</strong><strong>Criteria</strong>(EHC)<br />
Monographs<br />
http://inchem.org/pages/ehc.html 1990 29/04/2009 TheInternationalAgency<strong>for</strong><br />
ResearchonCancerWorking<br />
Group(IARC,1980)evaluated<br />
thecarcinogenicityofbarium<br />
chromate(VI)andconcluded<br />
thatitisapositivehuman<br />
carcinogen.Thecarcinogenic<br />
propertyofthiscompound,<br />
however,hasbeenascribedto<br />
thechromium(VI)moietyand<br />
nottothebarium.<br />
DutchNationalInstitute<strong>for</strong>Public<strong>Health</strong><br />
andtheEnvironment(RIVM)Maximum<br />
Permissible<strong>Risk</strong>(MPR)levels<br />
http://www.rivm.nl/en/ 01/12/1992 29/04/2009 NoHCV Chronictoxicity Toxicitystudyoffreshwaterorganisms<br />
USAgency<strong>for</strong>ToxicSubstancesandDiseasehttp://www.atsdr.cdc.gov/ 01/08/2007 29/04/2009 Generallynegativeresultsin<br />
Registry(ATSDR)ToxicologicalProfilesand<br />
genotoxicitystudies.<br />
Minimal<strong>Risk</strong>levels<br />
Insufficientdata<strong>for</strong>assessment<br />
USEPAIntegrated<strong>Risk</strong>In<strong>for</strong>mationSystem<br />
(IRIS)<br />
http://epa.gov/iris/ 11/07/2005 29/04/2009 Theresultsoftheoral<br />
carcinogenicitystudysuggest<br />
thatbariumisnotlikelytobe<br />
carcinogenictohumans.<br />
IDinhal<br />
Recommended<br />
IDinhal<br />
None<br />
Units<br />
Justification<br />
Insufficientdata<br />
Organisation WebLink LastUpdated DateWebChecked Nonthresholdeffects Basis <strong>Health</strong>criteria Value Units Confidencerating Basis Studytype Description<br />
type<br />
DutchNationalInstitute<strong>for</strong>Public<strong>Health</strong> http://www.rivm.nl/en/<br />
andtheEnvironment(RIVM)Maximum<br />
Permissible<strong>Risk</strong>(MPR)levels<br />
01/12/1992 29/04/2009 Chronictoxicity Toxicitystudyoffreshwaterorganisms<br />
Page 3 of 8<br />
EIC Pro<strong>for</strong>ma barium.xls 17/11/2009
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