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Soil Generic Assessment Criteria for Human Health Risk ... - ESdat

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www.esdat.net Esdat Environmental Database Management Software +61 2 8875 7948<br />

Barium<br />

TDIoral<br />

Organisation<br />

Targetorgan/CriticalEffect Reference Weblink<br />

FoodStandardsAgency(FSA)<br />

CommitteeontheToxicityofChemicalsin<br />

Food,ConsumerProductsandthe<br />

Environment(COT)<br />

IPCSconciseInternationalChemical<br />

<strong>Assessment</strong>Documents(CICADs)<br />

Noeffects<br />

Noeffects<br />

ThisstudydidnotidentifyaLOAEL<br />

WHO(2001b).ConciseInternationalChemical<strong>Assessment</strong>Document33: http://cot.food.gov.uk/pdfs/tox200837.pdf<br />

Bariumandbariumcompounds.World<strong>Health</strong>Organization,Geneva.InCOT<br />

2006UKTotaldietstudyofmetalsandotherelements<br />

WHO(2001b).ConciseInternationalChemical<strong>Assessment</strong>Document33: http://cot.food.gov.uk/pdfs/tox200837.pdf<br />

Bariumandbariumcompounds.World<strong>Health</strong>Organization,Geneva.InCOT<br />

2006UKTotaldietstudyofmetalsandotherelements<br />

WonesRG,StadlerBL,FrohmanLA(1990)Lackofeffectofdrinkingwater<br />

bariumoncardiovascularriskfactors.Environmentalhealthperspectives,<br />

85:1–13.WithinConciseInternationalChemical<strong>Assessment</strong>Document33<br />

BariumandBariumCompounds,WHO,Geneva2001<br />

http://inchem.org/documents/cicads/cicads/cicad33.htm<br />

Organisation<strong>for</strong>EconomicCooperation<br />

andDevelopment(OECD)Screening<br />

In<strong>for</strong>mationDataSet(SIDS)<strong>for</strong>High<br />

ProductionVolumeChemicals<br />

DutchNationalInstitute<strong>for</strong>Public<strong>Health</strong><br />

andtheEnvironment(RIVM)Maximum<br />

Permissible<strong>Risk</strong>(MPR)levels.<br />

http://www.inchem.org/documents/sids/sids/5160021.pdf<br />

Towardsintegratedenvironmentalqualityobjectives<strong>for</strong>surfacewater,<br />

groundwater,sedimentandsoil<strong>for</strong>ninetracemetalsPlasscheEJvande,<br />

BruijnJHMdeRIVMRapport679101005<br />

http://www.rivm.nl/bibliotheek/rapporten/679101005.pdf<br />

<strong>Health</strong>CanadaToxicologicalValues<br />

Noadverseeffectsonbloodpressureor<br />

cardiovasculardisease<br />

Brenniman,G.R.andLevy,P.S.EpidemiologicalstudyinIllinoisdrinking<br />

watersupplies.In:Advancesinmodernenvironmentaltoxicology.Vol.IX.<br />

PrincetonPublishingCo.,Princeton,NJ.p.231(1985).<br />

http://www.hcsc.gc.ca/ewhsemt/pubs/watereau/bariumbaryum/index<br />

eng.php#<strong>Health</strong><br />

USAgency<strong>for</strong>ToxicSubstancesandDiseaseModeratetomarkedseverity<br />

Registry(ATDSR)ToxicologicalProfilesand nephropathy,whichresultedinmarked<br />

Minimal<strong>Risk</strong>levels<br />

weightlossandincreasedmortality.<br />

NTP.1994.Toxicologyandcarcinogenesisstudiesofbariumchloride<br />

dihydrate(CASNo.10326279)inF344/NratsandB6C3F1mice(drinking<br />

waterstudies).U.S.Departmentof<strong>Health</strong>and<strong>Human</strong>Services,Public<br />

<strong>Health</strong>Service,NationalInstitutesof<strong>Health</strong>,NationalToxicologyProgram,<br />

ResearchTrianglePark,NC.NTPTR432.<br />

http://www.atsdr.cdc.gov/toxprofiles/tp24.pdf<br />

USEPA<strong>Health</strong>Advisors<br />

USEPAIntegrated<strong>Risk</strong>In<strong>for</strong>mationSystem<br />

(IRIS)<br />

Chemicalrelatednephropathywas<br />

observedinmaleandfemalemice<br />

followingchronicorsubchronicdrinking<br />

waterexposuretobariumchloride.These<br />

lesionswerecharacterizedbytubule<br />

dilatation,renaltubuleatrophy,tubulecell<br />

regeneration,hyalinecast<strong>for</strong>mation,<br />

multifocalinterstitialfibrosis,andthe<br />

presenceofcrystals,primarilyinthe<br />

lumenoftherenaltubules.<br />

USEPADrinkingWaterStandardsand<strong>Health</strong>Advisories,2006<br />

http://www.epa.gov/waterscience/criteria/drinking/dwstandards.html#ino<br />

rganics<br />

NationalToxicologyProgram(NTP).(1994)Technicalreportonthe http://www.epa.gov/ncea/iris/subst/0010.htm<br />

toxicologyandcarcinogenesisstudiesofbariumchloridedihydrate(CASNo.<br />

10326279)inF344/NratsandB6C3F1mice(drinkingwaterstudies).NTP<br />

TR432.NationalToxicologicalProgram,ResearchTrianglePark,NC.NIH<br />

Pub.No.943163.NTISPubPB94214178.<br />

Page 2 of 8<br />

EIC Pro<strong>for</strong>ma barium.xls 17/11/2009

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