Soil Generic Assessment Criteria for Human Health Risk ... - ESdat

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www.esdat.net Esdat Environmental Database Management Software +61 2 8875 7948 Styrene CAS 100-42-5 Assessor A: Nick Brown Grontmij Assessor B: Catherine Helm WD Environmental Final Review Panel/SF Date 29/05/2009 Date 01/06/2009 Date 28-Aug-09 Dutch National Institute for Public Health and the Environment (RIVM) Maximum Permissible Risk (MPR) Levels 14/04/2009 Air 5 ug/kg-bw/day Inhalation of air is assumed to account for all significant intake of Styrene in the Netherlands RIVM Report 711701 025. Re-evaluation of human toxicological maximum permissible risk levels A.J. Bars, R.M.C Theelan, P.J.C.M. Janssen, J.M. Hesse, M.E. van Apeldoorn, M.C.M. Meijerink, L.Verdam, M.J.Zeilmaker March 2001 http://www.rivm.nl/bibliotheek /rapporten/711701025.pdf Health Canada Toxicological Values 14/04/2009 Indoor Air 0.28 ug/m3 National Pilot Study in Canadian Homes (757 homes). NB. the mean concentration is misquoted as 280ug/m3 on the Health Canada Website however the correct value can be found within the folowing reference: Exposure to Styrene in the General Canadian Puopulation, Newhook R & Caldwell I, IARC Sci. Publication, 1993; 127, 27-33 Primary Reference cited as Concord Environmental, 1992 http://www.hc-sc.gc.ca/ewh- semt/pubs/contaminants/psl1- lsp1/stryene/styrene_3-eng.php 14/04/2009 Ambient air 0.09 - 2.35 ug/m3 Mean concentrations recorded at 18 site in 5 provinces Primary Reference cited as Dann, 1990 US Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles and Minimal Risk Levels 14/04/2009 14/04/2009 Ambient air 0.11-0.36 ug/m3 Concentrations recorded in Chilba City Japan by ATSDR, Toxicological Profile for Styrene. Update. Draft for Uchiyama and Hasegawa (2000) Public Comment. September 2007 Ambient air 0.1 ug/m3 Average concentration recorded in Minnesota (Pratt et al. 200) Median concentration was 0.08 and maximum was 1.49 http://www.atsdr.cdc.gov/toxpr ofiles/tp53.html Indoor air 0.1-50 ug/m3 Estimate: Primary data source unclear Polluted urban air 400 ug/day Estimate of nominal ADI - US. Urban air 6 ug/day Indoor air 6-1000 ug/day Toxicological Data Network (TOXNET) 31/03/2009 IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Geneva, Switzerland: World Health Org, Inter Agency Res Cancer. 60: 248 (1994) http://toxnet.nlm.nih.gov/ Page 4 of 4 EIC Proforma styrene.xls 28/08/2009
www.esdat.net Esdat Environmental Database Management Software +61 2 8875 7948 Substance: Styrene CAS Number: 100-42-5 Assessor A Claire Potter Grontmij Assessor B Catherine Helm WD Final review Panel/SF Chemical Formula: C6H8 Phase at Ambient Liquid Tempertaure Date: 01-Apr-09 Date: 01/06/2009 Date: 28/08/2009 http://srdata.nist.gov/solubility/ http://webbook.nist.gov/chemistry/ http://cs3-hq.oecd.org/scripts/hpv/ A B C D E F G H Property Units Calculated Value Adopted Value Ref. Temp (C) Rationale References HOWARD, 1990 LIDE, 2008 MACKAY et al, 2006 MERCK, 2006 MONTGOMERY, 2007 MONTGOMERY, 1997 NIST, 2005 OECD, 2000 Source Units SR7 Units Ref. Temp (C) Source Units SR7 Units Ref. Temp (C) Source Units SR7 Units Ref. Temp (C) Source Units SR7 Units Ref. Temp (C) Source Units SR7 Units Ref. Temp (C) Source Units SR7 Units Ref. Temp (C) Source Units SR7 Units Ref. Temp (C) Source Units SR7 Units Ref. Temp (C) Required Parameters Relative Molecular Mass g mol -1 n/a 104.15 n/a Median value from consistent (high) range of literature values g mol -1 g mol -1 Ref. Temp (C) g mol -1 g mol -1 Ref. Temp (C) g mol -1 g mol -1 Ref. Temp (C) g mol -1 g mol -1 Ref. Temp (C) g mol -1 g mol -1 Ref. Temp (C) g mol -1 g mol -1 Ref. Temp (C) g mol -1 g mol -1 Ref. Temp (C) g mol -1 g mol -1 Ref. Temp (C) Average 104.16 n/a 104.15 n/a 104.14 n/a 104.15 n/a 104.15 n/a Insert Values n/a 104.1491 n/a 104.14 n/a 104.16 104.16 n/a 104.15 104.15 n/a 104.14 104.14 n/a 104.15 104.15 n/a 104.15 104.15 n/a n/a 104.1491 104.1491 n/a 104.14 104.14 n/a atm m3 mol-1 Pa m3 mol-1 Ref. Temp (C) KPa m3 mol-1 Pa m3 mol-1 Ref. Temp (C) Pa m3 mol-1 Pa m3 mol-1 Ref. Temp (C) n/a n/a n/a atm m3 mol-1 Pa m3 mol-1 Ref. Temp (C) atm m3 mol-1 Pa m3 mol-1 Ref. Temp (C) mol kg-1 bar-1 Pa m3 mol-1 Ref. Temp (C) atm m3 mol-1 Pa m3 mol-1 Ref. Temp (C) Henry's Law Constant (HLC) Pa m3 mol-1 n/a 2.86E+02 25 Adopted value is that from the newest source (Lide 2008) as no consistent range Geomean 2.85E+02 25 2.86E+02 25 2.69E+02 25 2.64E+02 25 Insert Values 25 2.91E+02 25 2.85E+02 25 2.81E-03 2.85E+02 2.86E-01 2.86E+02 2.33E+02 233 2.61E-03 264.45825 3.70E-01 2.71E+02 284.72 285 285 0.29 3.46E+02 25 267 267 0.38 2.64E+02 297 297 No ref. temp, n/a n/a n/a 25 25 25 25 Howard 1989 is referenced. mg/L mg/L Ref. Temp (C) g/L mg/L Ref. Temp (C) mg/L mg/L Ref. Temp (C) mg/L mg/L Ref. Temp (C) mg/L mg/L Ref. Temp (C) mg/L mg/L Ref. Temp (C) mg/L mg/L Ref. Temp (C) mg/L mg/L Ref. Temp (C) Geomean 3.10E+02 25 3.21E+02 25 2.90E+02 10 Insert Values Insert Values Insert Values 2.90E+02 10 3.00E+02 20 3.10E+02 3.10E+02 3.21E-01 321 2.90E+02 2.90E+02 Shaw, 1989 2.90E+02 2.90E+02 Lane, 1946 3.00E+02 3.00E+02 Solubility (S) 10 oC where possible. (Use unit converter if source provides different units) mg/L n/a 2.90E+02 10 Consistent value from two sources at 10 degrees value not provided 'sparingly soluble' Chemical Boiling Point (ambient pressure) Chemical Melting Point (ambient pressure) Log Octanol - Water Coefficient Molar Volume (Le Bas method) K n/a 418 K Dimensionless cm3 mol-1 n/a n/a n/a 243 2.98 n/a n/a n/a 133 n/a Median value from consistent range of literature values Median value from consistent range of literature values Median value from consistentrange of literature values Single literature value available o C K Ref. Temp (C) o C K Ref. Temp (C) o C K Ref. Temp (C) o C K Ref. Temp (C) o C K Ref. Temp (C) o C K Ref. Temp (C) K K Ref. Temp (C) o C K Ref. Temp (C) Average 4.18E+02 n/a 4.18E+02 n/a 4.18E+02 n/a 4.19E+02 n/a 4.18E+02 n/a Insert Values n/a 4.19E+02 n/a 4.18E+02 n/a 145.2 418.35 n/a 145 418.15 n/a 145 418.15 n/a 145 418.15 n/a 145.2 418.35 n/a n/a 417 417.00 n/a 145.2 418.35 n/a n/a n/a n/a 146 419.15 n/a n/a n/a 419 419.00 n/a n/a n/a n/a n/a n/a n/a n/a 421 421.00 n/a n/a o C K Ref. Temp (C) o C K Ref. Temp (C) o C K Ref. Temp (C) o C K Ref. Temp (C) o C K Ref. Temp (C) o C K Ref. Temp (C) K K Ref. Temp (C) o C K Ref. Temp (C) Average 2.43E+02 n/a 2.43E+02 n/a 2.43E+02 n/a 2.43E+02 n/a 2.41E+02 n/a Insert Values n/a 2.41E+02 n/a 2.43E+02 n/a -30.63 242.52 n/a -30.65 242.50 n/a -30.65 242.50 n/a -30.6 242.55 n/a -30.6 242.55 n/a n/a 233 233.00 n/a -30.63 242.52 n/a n/a n/a n/a n/a -33 240.15 n/a n/a 241 241.00 n/a n/a n/a n/a n/a n/a n/a n/a 249 249.00 n/a n/a Dimensionless Dimensionless Ref. Temp (C) Dimensionless Dimensionless Ref. Temp (C) Dimensionless Dimensionless Ref. Temp (C) Dimensionless Dimensionless Ref. Temp (C) Dimensionless Dimensionless Ref. Temp (C) Dimensionless Dimensionless Ref. Temp (C) Dimensionless Dimensionless Ref. Temp (C) Dimensionless Dimensionless Ref. Temp (C) Average 2.95E+00 n/a 3.05E+00 n/a 2.99E+00 n/a Insert Values n/a 2.96E+00 n/a Insert Values n/a Insert Values n/a 2.98E+00 n/a 2.95 2.95 n/a 3.05 3.05 n/a 3.14 3.14 n/a n/a 2.76 2.76 n/a n/a n/a 2.95 2.95 n/a n/a n/a 2.95 2.95 n/a n/a 3.16 3.16 n/a n/a n/a 3 3.00 n/a n/a n/a 3.16 3.16 n/a n/a 2.95 2.95 n/a n/a n/a n/a n/a n/a 2.76 2.76 n/a n/a n/a n/a n/a n/a n/a n/a 2.9 2.90 n/a n/a n/a n/a n/a n/a n/a n/a 3.05 3.05 n/a n/a n/a n/a n/a n/a n/a n/a 2.95 2.95 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a cm3 mol-1 cm3 mol-1 Ref. Temp (C) Average n/a n/a n/a n/a n/a n/a 1.33E+02 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a 133 133.00 n/a Calculated Value KJ mol-1 J Mol-1 KJ mol-1 J Mol-1 KJ mol-1 J Mol-1 Ref. Temp (C) Enthalpy of Vaporisation at Normal Average 3.87E+04 4.13E+04 4.38E+04 normal boiling point J Mol-1 36807.58889 3.68E+04 Chemical n/a n/a n/a 38.7 38700 43.932 43932 n/a n/a n/a n/a n/a n/a n/a n/a n/a 43.51 43510 n/a n/a n/a Normal Normal Normal (EVNBP) Boiling Point 38.7 38700 43.93 43930 Boiling Boiling Boiling 44.35 44350 Point Point Point 43.5 43500 Calculated Value K K Ref. Temp (C) o C K Ref. Temp (C) K K Ref. Temp (C) o C K Ref. Temp (C) Chemical Critical Point Average 6.35E+02 n/a Insert Values n/a Insert Values n/a Insert Values n/a temperature K 634.6834782 634.7 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a 635.2 635.20 n/a n/a n/a n/a (ambient pressure) n/a n/a n/a n/a n/a n/a n/a n/a Calculated Value Bar Atmosph Ref. Temp (C) Bar Atmosph Ref. Temp (C) Average 3.82E+01 Insert Values 38.7 38.19393042 Critical Pressure atm 37.79576136 37.80 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a Calcuated parameters for input to CLEA model (UPDATED FROM THE SPREADSHEET TOOL) Property Units Calculated Value Ref. Temp (C) Rationale Property Units Calculated Value Ref. Temp (C) Rationale Property Units Calculated Value Ref. Temp (C) Rationale Property Units Calculated Value Ref. Temp (C) Rationale Property Units Calculated Value Ref. Temp (C) Rationale Air-water partition coefficient at ambient soil temperature cm 3 .cm -3 5.334E-02 10 Estimated from parameters above using Clapyron relationship or direct calculation Vapour pressure at ambient soil temperature Pa 350 10 Estimated from parameters above using Grain-Watson method Diffusion coefficient in air m 2 .s -1 7.19E-06 10 Estimated from parameters above using Wilkie-Lee method Diffusion coefficient in water m 2 .s -1 5.48E-10 10 Estimated from parameters above using Hayduk and Laudie method Organic carbon-water partition coefficient Log cm 3 .g -1 2.51 n/a Estimated from parameters above using equation in Table 2.12 of SR7 Page1 of 1 EIC Proforma styrene.xls28/08/2009
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