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Soil Generic Assessment Criteria for Human Health Risk ... - ESdat

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Methyl tert-butyl ether CAS Number: 1634-04-4<br />

Assessor A: Cheryl Davies, Delta-<br />

Simons<br />

Assessor B: Jennifer<br />

Stothert, Entec<br />

UK Ltd<br />

Final Review: Panel/SF<br />

Date 01/03/2009 Date 27/04/2009 date: 26/08/2009<br />

ID inhal Recommended IDinhal Units Justification<br />

Consensus that MTBE not genotoxic<br />

Organisation Web Link Last Updated Date Web Checked Non threshold effects Basis <strong>Health</strong> criteria Value Units Confidence rating<br />

Basis<br />

Study type<br />

type<br />

European Chemicals Bureau<br />

(ECB)<br />

http://ecb.jrc.it/ 2002 27/04/2009 MTBE is not a<br />

genotoxic substance 400 ppm NOAEC<br />

International Agency <strong>for</strong><br />

Research on Cancer (IARC)<br />

http://inchem.org/pages/iarc.ht<br />

ml<br />

Sep-99 27/04/2009<br />

The data indicate that<br />

methyl tert-butyl ether<br />

is not genotoxic<br />

IPCS Environmental <strong>Health</strong><br />

<strong>Criteria</strong> (EHC) Monographs<br />

http://inchem.org/pages/ehc.ht<br />

ml<br />

1998 27/04/2009 The weight of evidence<br />

indicates that MTBE is<br />

not genotoxic.<br />

Dutch National Institute <strong>for</strong><br />

Public <strong>Health</strong> and the<br />

Environment (RIVM)<br />

Maximum Permissible <strong>Risk</strong><br />

(MPR) levels<br />

http://www.rivm.nl/en/ 2004 27/04/2009 The weight of evidence<br />

indicates that MTBE is<br />

not genotoxic.<br />

5 of 6 C:\Firth Consultants\projects\eic\EIC GAC\3rd phase\Final Pro<strong>for</strong>mas\EIC Pro<strong>for</strong>ma MTBE.xls26/08/2009

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