Soil Generic Assessment Criteria for Human Health Risk ... - ESdat
Soil Generic Assessment Criteria for Human Health Risk ... - ESdat
Soil Generic Assessment Criteria for Human Health Risk ... - ESdat
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Di n butyl phthalate, Di butyl phthalate or<br />
DBP<br />
USEPA Integrated <strong>Risk</strong> In<strong>for</strong>mation System<br />
(IRIS)<br />
http://www.epa.gov/ncea/iris/subst/0038.htm<br />
ID inhal<br />
Organisation<br />
<strong>Health</strong> and Safety Executive (HSE)<br />
Study type Description Response Reference Web link<br />
http://www.hse.gov.uk/aboutus/meetings/hscarchive/2004/091104/c06c.p<br />
df<br />
European Chemicals Bureau (ECB)<br />
European Union <strong>Risk</strong> <strong>Assessment</strong> Report Volume 29 , 2003 with addendum<br />
2004<br />
http://ecb.jrc.ec.europa.eu/DOCUMENTS/Existing-<br />
Chemicals/RISK_ASSESSMENT/REPORT/dibutylphthalatereport003.pdf<br />
Scientific Committee on Food (SCF) pre 2002<br />
Available limited 90-day and 1 year oral rat studies oral<br />
reproduction and tetratogenicity studies, limited<br />
mutagenicity studies (RIVM May 1998). Needed : tests<br />
<strong>for</strong> gene mutation and if migration exceeds 0.05mg/kg<br />
28 oral study and peroxisome proliferation study too.<br />
Compilation of the Evaluations of the scientific committee on food on certain<br />
monomers and additives used in the manufacture of plastics materials<br />
intended to come into contact with food Stuffs Until 21 March 1997 SCF<br />
1999<br />
http://ec.europa.eu/food/fs/sc/scf/reports/scf_reports_42.pdf<br />
Dutch National Institute <strong>for</strong> Public <strong>Health</strong><br />
and the Environment (RIVM) Maximum<br />
Permissible <strong>Risk</strong> (MPR) levels<br />
Baars et al states that inhalation not considered<br />
relevant due to low volatility. The dust paper uses the<br />
oral EFSA value given above<br />
re-evaluation of maximum permissible levels By Baars et al RIVM<br />
711701025/2001 superseded by RIVM Report 609021064/2008 Exposure to<br />
chemicals via house dust A. G. Oomen P. J.C.M. Janssen A. Dusseldorp C. W.<br />
Noorlander<br />
http://www.rivm.nl/bibliotheek/rapporten/609021064.pdf &<br />
http://www.rivm.nl/bibliotheek/rapporten/711701025.pdf (Baars et al)<br />
<strong>Health</strong> Canada Toxicological Values<br />
Inhalation not specifically addressed. The weight of<br />
available data in in vitro assays indicates that dibutyl<br />
phthalate is not genotoxic. Carcinogenicity is<br />
potentially the most sensitive endpoint. No human<br />
epidemiological studies to assess carcinogenicity and<br />
available data considered inadequate to assess the<br />
carcinogenicity animals.<br />
Dibutyl Phthalate - PSL1<br />
http://www.hc-sc.gc.ca/ewh-semt/pubs/contaminants/psl1-<br />
lsp1/phthalate_dibutyl_phtalate/phthalate_dibutyl_phtalate_3-eng.php<br />
USEPA Integrated <strong>Risk</strong> In<strong>for</strong>mation System<br />
(IRIS)<br />
Basis — Pertinent data regarding carcinogenicity was<br />
not located in the available literature.<br />
http://www.epa.gov/ncea/iris/subst/0038.htm<br />
Page 8 of 8<br />
EIC pro<strong>for</strong>ma Di n butyl phthalate.xls26/08/2009
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