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Butyl benzyl phthalate CAS Number: 85-68-7 Assessor A: N Struggles, AECOM Assessor B: Atkins Final review: Panel/SF<br />

Date 01/06/2009 Date 17/06/2009 Date 26/08/2009<br />

ID oral Recommended IDoral Units<br />

None<br />

Organisation Web Link Last Updated Date Web Checked Non threshold effects Basis <strong>Health</strong> criteria<br />

type<br />

IPCS concise International Chemical <strong>Assessment</strong> Documents (CICADs) http://inchem.org/pages/cicads.html No data 01/06/2009 Weight of evidence is that BBP<br />

is not a human carcinogen<br />

Justification<br />

Insufficient data<br />

Value Units Confidence rating<br />

Basis<br />

Study type<br />

Dutch National Institute <strong>for</strong> Public <strong>Health</strong> and the Environment (RIVM)<br />

Maximum Permissible <strong>Risk</strong> (MPR) levels<br />

http://www.rivm.nl/en/ No data 01/06/2009 Conclude little evidence that<br />

BBP is a human carcinogen.<br />

USEPA Integrated <strong>Risk</strong> In<strong>for</strong>mation System (IRIS) http://epa.gov/iris/ 28/10/2003 01/06/2009 Possible human carcinogen<br />

Based on statistically<br />

significant increase in<br />

mononuclear cell leukaemia in<br />

female rats; the response in<br />

male rats was inconclusive and<br />

there was no such response in<br />

mice.<br />

ID inhal<br />

Recommended IDinhal Units<br />

None<br />

Justification<br />

Insufficient data<br />

Organisation Web Link Last Updated Date Web Checked Non threshold effects Basis <strong>Health</strong> criteria<br />

type<br />

IPCS concise International Chemical <strong>Assessment</strong> Documents (CICADs) http://inchem.org/pages/cicads.html No data 01/06/2009 Weight of evidence is that BBP<br />

is not a human carcinogen<br />

Value Units Confidence rating<br />

Basis<br />

Study type<br />

Dutch National Institute <strong>for</strong> Public <strong>Health</strong> and the Environment (RIVM)<br />

Maximum Permissible <strong>Risk</strong> (MPR) levels<br />

http://www.rivm.nl/en/ No data 01/06/2009 Conclude little evidence that<br />

BBP is a human carcinogen.<br />

USEPA Integrated <strong>Risk</strong> In<strong>for</strong>mation System (IRIS) http://epa.gov/iris/ No data 01/06/2009 Possible human carcinogen<br />

Based on statistically<br />

significant increase in<br />

mononuclear cell leukaemia in<br />

female rats; the response in<br />

male rats was inconclusive and<br />

there was no such response in<br />

mice.<br />

Page 3 of 4 EIC pro<strong>for</strong>ma butyl benzyl phthalate.xls 26/08/2009

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