Soil Generic Assessment Criteria for Human Health Risk ... - ESdat

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Bromoform CAS 75-25-2 Assessor A:
J Brown - DTS
Raeburn Assessor B: A Fellows - Ecologia Final review: Panel/SF
Date 05/04/2009 Date 06/04/2009 Date 28/08/2009
MDI
Recommended
MDIoral
Units
42 ug day-1
Justification: ATSDR exposure value from drinking water, converted assuming an adult bodyweight (x 70kg). Exposure still
fairly conservative in consideration of the COT report. COT data is inappropriate as document is for 'members use only'.
Organisation Date Media Value Units Description Reference Web link
Committee on Toxicity of
Chemicals in Food, Consumer
Products and the Environment
(COT)
2001 drinking water 70 ug day-1 uk specific exposure
from drinking water
"in the order of
1ug/kg/day"
Committee on the Toxicity of Chemicals in Food, Consumer
Products and the Environment, TOX/2001/16 - A Sahsu Study
on Chlorination Disinfection By-Products and Birth Outcomes
in 3 Water Areas in England, 2001 (For members use only)
www.cot.food.gov.uk
US Agency for Toxic Substances
and Disease Registry (ATSDR)
Toxicological Profiles and
Minimal Risk Levels
2005 drinking water 42 ug day-1 converted from
0.6ug/kg/day
ATSDR, Toxicological Profile for Bromoform and
Dibromochloromethane, 2005
www.atsdr.cdc.gov/
USEPA Health Advisories 2005 drinking water 2.4 ug day-1 Median surface
supplies exposure
EPA Office of Water, Drinking Water Criteria Document for
Brominated Trihalomethanes, 2005
www.epa.gov/waterscience/criteria/drink
ing/
Recommended
MDIinhal
Units
Justification: RIVM report. Value is also most conservative, converted assuming an adult bodyweight (x 70kg). In close
agreement with USEPA value for outdoor air
70 ug day-1
Organisation Date Media Value Units Description Reference Web link
Dutch National Institute for
Public Health and the
Environment (RIVM) Maximum
Permissible Risk (MPR) Levels
2005 air 70 ug day-1 converted from
background
exposure of