Soil Generic Assessment Criteria for Human Health Risk ... - ESdat

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Barry Mitcheson,
Bis(2 ethylhexyl)phthalate CAS 117-81-7 Assessor A: Enviros Assessor B: Charlotte Clark, Hyder Final review: Panel/SF
Date 06/05/2009 Date 06/05/2009 Date 26/08/2009
20/04/2009 Abstract
of paper only (2003)
20/04/2009 Abstract
of paper only (2008)
20/04/2009 Abstract
of paper only (2006)
median intake 13.8ug/kg bw/day 966ug/day
(assumes 70kg
bw)
median intake 2.7ug/kg bw/day 189ug/day
(assumes 70kg
bw)
daily intake 21ug/kg bw/day 1750ug/day
(assumes 70kg
bw)
Based on analysed urine samples from general german
population
Based on urine analysis of 102 german subjects
General population 95th percentile value. Children value is
25ug/kg bw/day
An estimation of the daily intake of di(2-ethylhexyl)phthalate (DEHP) and other
phthalates in the general population. Int J Hyg Environ Health. 2003 Mar;206(2):77-83
Phthalates: metabolism and exposure. Int J Androl. 2008 Apr;31(2):131-8. Epub 2007
Dec 7
Di(2-ethylhexyl)phthalate (DEHP): human metabolism and internal exposure - an
update and latest results. Int J Androl. 2006 Feb;29(1):155-65; discussion 181-5.
MDI Recommended MDIinh Units Justification: Value selected by ECB for adult exposure indoors, WHO has advised that exposure in cities typically less than 1ug/d therefore other
15 ug day-1 inhalation sources not considered.
Organisation Date Media Value Units Description Reference Web link
European Chemicals Bureau (ECB) 12/04/2009 Indoor air exposure 15.4ug/day ”Indoor air” (building materials) 4.4ug/kgbw/day based on
concentration of 0.021mg/m3 for a 70kg adult inhaling
20m3
12/04/2009 Indoor air exposure 19.3ug/day ”Indoor air” (building materials) 22.4ug/kgbw/day based
on concentration of 0.021mg/m3 for an 8kg adult inhaling
European Centre for Ecotoixcology
and Toxicology of Chemicals
(ECETOC)
International Agency for Research
on Cancer (IARC)
IPCS Environmental Health Criteria
(EHC) Monographs
WHO Guidelines for Drinking Water
Quality
Dutch National Institute for Public
Health and the Environment (RIVM)
Maximum Permissable Risk (MPR)
Levels
9.3m3
22/04/09 (1998) indoor air 50ug/m3 100ug/day value for indoor air. Value for city air stated as 5-
132ng/m3 which is low compared to indoor air.
22/04/09 (2004) indoor air exposure for
children
12/04/2009 Ambient air limit