Soil Generic Assessment Criteria for Human Health Risk ... - ESdat
Soil Generic Assessment Criteria for Human Health Risk ... - ESdat
Soil Generic Assessment Criteria for Human Health Risk ... - ESdat
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4-Methylphenol CAS 106-44-5 Assessor A: Gareth Wills Assessor B: Mat Rouge Final Review: Panel/SF<br />
Date 08/04/2009 Date 15/04/2009 Date 28/08/2009<br />
MDI<br />
Recommended<br />
MDIoral<br />
Units<br />
0 ug day-1<br />
Justification: No data, background exposure assumed negligible in comparison to HCV. HCV is equivalent to drinking water concentration of 3500μg/L based on a 70kg adult consuming<br />
2L/day.<br />
Organisation Date Media Value Units Description Reference Web link<br />
IPCS Environmental <strong>Health</strong><br />
<strong>Criteria</strong> (EHC) Monographs<br />
1995 air, drinking water,<br />
food<br />
No data<br />
Due to the lack of adequate monitoring data, it is not<br />
possible to estimate the daily intake of cresols from<br />
these sources<br />
Cresols - (Environmental health criteria ; 168) ISBN 92 4 157168 1 (NLM<br />
Classification: QV 223) ISSN 0250-863X<br />
http://inchem.org/documents/ehc/ehc/ehc168.htm<br />
drinking water No data No quantitative data available regarding cresol levels in<br />
drinking water in USA are available<br />
MDI Recommended MDIinh Units<br />
0.634 ug day-1<br />
Justification: Cresols not widely occurring atmospheric pollutants. ATSDR data selected as most recent representative of background exposure = 31.7ng/m3 converted assuming an adult<br />
breathes 20m3/day.<br />
Organisation Date Media Value Units Description Reference Web link<br />
IPCS Environmental <strong>Health</strong><br />
http://inchem.org/documents/ehc/ehc/ehc168.htm<br />
<strong>Criteria</strong> (EHC) Monographs<br />
US Agency <strong>for</strong> Toxic Substances<br />
and Disease Registry (ATSDR)<br />
Toxicological Profiles and<br />
Minimal <strong>Risk</strong> Levels<br />
Toxicological Data Network<br />
(TOXNET)<br />
1995 air 100000 ug day-1 in air samples from rooms with a fireplace, cresol<br />
concentrations around 5 mg/m3 have been detected.<br />
This converts to 100,000 ug day based on the CLEA<br />
calculations (20 m3 day air)<br />
2000 Ambient Air 0.634 ug day-1 Monitoring data have not shown cresols to be widely<br />
occurring atmospheric pollutants. A national emissions<br />
study conducted from 1990 to 1998 reported an<br />
estimated ambient concentration average of 31.7<br />
ng/m3<br />
1993 Ambient Air 28 ug day-1 Combined m,p-cresol isomers mean concn of 1.4 ug/m3<br />
(range, 0-4.1 ug/m3) in the US - converted to 28ug day,<br />
using CLEA intake value of 20 m3 a day<br />
Risner CH (1993) The quantification of hydroquinone,<br />
catechol, phenol,3-methylcatechol, scopoletin, m+pcresol<br />
and o- cresol in indoor air sample by high<br />
per<strong>for</strong>mance liquid chromatography. J LiqChromatogr,<br />
16:4117-4140.<br />
EPA. 2000. National air pollutant emission trends, 1900-1998. Research<br />
Triangle Park, NC: U.S. http://www.atsdr.cdc.gov/toxprofiles/tp34.pdf<br />
Kelly TJ et al; Ambient Concentration Summaries <strong>for</strong> Clean Air Act Title III<br />
Hazardous Air Pollutants. USEPA/600/R-94/090 Final Report Research<br />
Triangle Park (1993)<br />
http://www.atsdr.cdc.gov/toxprofiles/tp34.html<br />
http://toxnet.nlm.nih.gov/cgi-bin/sis/search/f./temp/~VaK2Cn:1<br />
(Page 1 of 1) (EIC pro<strong>for</strong>ma 4-methylphenol.xls 28/08/2009)
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