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Soil Generic Assessment Criteria for Human Health Risk ... - ESdat

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www.esdat.net Esdat Environmental Database Management Software +61 2 8875 7948<br />

2-Methylphenol CAS 95-48-7 Assessor A: Gareth Wills Assessor B: Mat Rouge Final Review: Panel/SF<br />

Date 08/04/2009 Date 15/04/2009 Date 28/08/2009<br />

MDI<br />

Recommended<br />

MDIoral<br />

Units<br />

0 ug day-1<br />

Justification: No data, background exposure assumed negligible in comparison to HCV. HCV is equivalent to drinking water concentration of 3500μg/L based on a 70kg adult consuming<br />

2L/day.<br />

Organisation Date Media Value Units Description Reference Web link<br />

IPCS Environmental <strong>Health</strong><br />

<strong>Criteria</strong> (EHC) Monographs<br />

1995 air, drinking water,<br />

food<br />

No data<br />

Due to the lack of adequate monitoring data, it is not<br />

possible to estimate the daily intake of cresols from<br />

these sources<br />

Cresols - (Environmental health criteria ; 168) ISBN 92 4 157168 1 (NLM<br />

Classification: QV 223) ISSN 0250-863X<br />

http://inchem.org/documents/ehc/ehc/ehc168.htm<br />

drinking water No data No quantitative data available regarding cresol levels in<br />

drinking water in USA are available<br />

MDI Recommended MDIinh Units<br />

0.634 ug day-1<br />

Justification: Cresols not widely occurring atmospheric pollutants. ATSDR data selected as most representative of background<br />

exposure = 31.7ng/m3 converted assuming an adult breathes 20m3/day.<br />

Organisation Date Media Value Units Description Reference Web link<br />

IPCS Environmental <strong>Health</strong><br />

1995 Ambient Air 31.8 ug day-1 Environmental <strong>Health</strong> <strong>Criteria</strong> 168 - Reports the median Cresols - (Environmental health criteria ; 168) ISBN 92 4 157168 1 (NLM http://inchem.org/documents/ehc/ehc/ehc168.htm<br />

<strong>Criteria</strong> (EHC) Monographs<br />

air concentration of o-cresols was 1.59 μg/m3 (0.359 Classification: QV 223) ISSN 0250-863X<br />

ppb) <strong>for</strong> 32 source-dominated sites in the USA. This<br />

converts to 31.8 ug day based on the CLEA calculations<br />

(20 m3 day air)<br />

air 100000 ug day-1 In air samples from rooms with a fireplace, cresol Risner CH (1993) The quantification of hydroquinone,<br />

concentrations around 5 mg/m3 have been detected.<br />

catechol, phenol,3-methylcatechol, scopoletin, m+pcresol<br />

and o- cresol in indoor air sample by high<br />

This converts to 100,000 ug day based on the CLEA<br />

per<strong>for</strong>mance liquid chromatography. J LiqChromatogr,<br />

calculations (20 m3 day air)<br />

16:4117-4140.<br />

US Agency <strong>for</strong> Toxic Substances<br />

and Disease Registry (ATSDR)<br />

Toxicological Profiles and<br />

Minimal <strong>Risk</strong> Levels<br />

Toxicological Data Network<br />

(TOXNET)<br />

2000 Ambient Air 0.634 ug day-1 Monitoring data have not shown cresols to be widely<br />

occurring atmospheric pollutants. A national emissions<br />

study conducted from 1990 to 1998 reported an<br />

estimated ambient concentration average of 31.7<br />

ng/m3<br />

1993 Ambient Air 1.4 ug day-1 Mean concn of 0.07 ug/m3 (range, 0-0.13 ug/m3) in the<br />

US - converted to 1.4ug day, using CLEA intake value of<br />

20 m3 a day<br />

EPA. 2000. National air pollutant emission trends, 1900-1998. Research<br />

Triangle Park, NC: U.S. http://www.atsdr.cdc.gov/toxprofiles/tp34.pdf<br />

Kelly TJ et al; Ambient Concentration Summaries <strong>for</strong> Clean Air Act Title III<br />

Hazardous Air Pollutants. USEPA/600/R-94/090 Final Report Research<br />

Triangle Park (1993)<br />

http://www.atsdr.cdc.gov/toxprofiles/tp34.html<br />

http://toxnet.nlm.nih.gov/cgi-bin/sis/search/f./temp/~rMogqz:1<br />

(Page 1 of 1) (EIC pro<strong>for</strong>ma 2-methylphenol.xls 28/08/2009)

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