Soil Generic Assessment Criteria for Human Health Risk ... - ESdat

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www.esdat.net Esdat Environmental Database Management Software +61 2 8875 7948 2-Methylphenol ID oral Organisation US Agency for Toxic Substances and Disease Registry (ATDSR) Toxicological Profiles and Minimal Risk levels Description Response Reference Web link n/a n/a n/a http://www.atsdr.cdc.gov/toxprofiles/tp34.html USEPA Integrated Risk Information System (IRIS) n/a n/a n/a http://epa.gov/iris/ US EPA Provisional Peer Reviewed Toxicity Values (PPRTV) n/a n/a n/a http://rais.ornl.gov/tox/unauthorized.shtml ID inhal Organisation US Agency for Toxic Substances and Disease Registry (ATDSR) Toxicological Profiles and Minimal Risk levels Description Response Reference Web link n/a n/a n/a http://www.atsdr.cdc.gov/toxprofiles/tp34.html USEPA Integrated Risk Information System (IRIS) n/a n/a n/a http://epa.gov/iris/ (Page 4 of 4) (EIC proforma 2-methylphenol.xls 28/08/2009)
www.esdat.net Esdat Environmental Database Management Software +61 2 8875 7948 2-Methylphenol CAS 95-48-7 Assessor A: Gareth Wills Assessor B: Mat Rouge Final Review: Panel/SF Date 08/04/2009 Date 15/04/2009 Date 28/08/2009 MDI Recommended MDIoral Units 0 ug day-1 Justification: No data, background exposure assumed negligible in comparison to HCV. HCV is equivalent to drinking water concentration of 3500μg/L based on a 70kg adult consuming 2L/day. Organisation Date Media Value Units Description Reference Web link IPCS Environmental Health Criteria (EHC) Monographs 1995 air, drinking water, food No data Due to the lack of adequate monitoring data, it is not possible to estimate the daily intake of cresols from these sources Cresols - (Environmental health criteria ; 168) ISBN 92 4 157168 1 (NLM Classification: QV 223) ISSN 0250-863X http://inchem.org/documents/ehc/ehc/ehc168.htm drinking water No data No quantitative data available regarding cresol levels in drinking water in USA are available MDI Recommended MDIinh Units 0.634 ug day-1 Justification: Cresols not widely occurring atmospheric pollutants. ATSDR data selected as most representative of background exposure = 31.7ng/m3 converted assuming an adult breathes 20m3/day. Organisation Date Media Value Units Description Reference Web link IPCS Environmental Health 1995 Ambient Air 31.8 ug day-1 Environmental Health Criteria 168 - Reports the median Cresols - (Environmental health criteria ; 168) ISBN 92 4 157168 1 (NLM http://inchem.org/documents/ehc/ehc/ehc168.htm Criteria (EHC) Monographs air concentration of o-cresols was 1.59 μg/m3 (0.359 Classification: QV 223) ISSN 0250-863X ppb) for 32 source-dominated sites in the USA. This converts to 31.8 ug day based on the CLEA calculations (20 m3 day air) air 100000 ug day-1 In air samples from rooms with a fireplace, cresol Risner CH (1993) The quantification of hydroquinone, concentrations around 5 mg/m3 have been detected. catechol, phenol,3-methylcatechol, scopoletin, m+pcresol and o- cresol in indoor air sample by high This converts to 100,000 ug day based on the CLEA performance liquid chromatography. J LiqChromatogr, calculations (20 m3 day air) 16:4117-4140. US Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles and Minimal Risk Levels Toxicological Data Network (TOXNET) 2000 Ambient Air 0.634 ug day-1 Monitoring data have not shown cresols to be widely occurring atmospheric pollutants. A national emissions study conducted from 1990 to 1998 reported an estimated ambient concentration average of 31.7 ng/m3 1993 Ambient Air 1.4 ug day-1 Mean concn of 0.07 ug/m3 (range, 0-0.13 ug/m3) in the US - converted to 1.4ug day, using CLEA intake value of 20 m3 a day EPA. 2000. National air pollutant emission trends, 1900-1998. Research Triangle Park, NC: U.S. http://www.atsdr.cdc.gov/toxprofiles/tp34.pdf Kelly TJ et al; Ambient Concentration Summaries for Clean Air Act Title III Hazardous Air Pollutants. USEPA/600/R-94/090 Final Report Research Triangle Park (1993) http://www.atsdr.cdc.gov/toxprofiles/tp34.html http://toxnet.nlm.nih.gov/cgi-bin/sis/search/f./temp/~rMogqz:1 (Page 1 of 1) (EIC proforma 2-methylphenol.xls 28/08/2009)
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