Soil Generic Assessment Criteria for Human Health Risk ... - ESdat
Soil Generic Assessment Criteria for Human Health Risk ... - ESdat
Soil Generic Assessment Criteria for Human Health Risk ... - ESdat
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www.esdat.net Esdat Environmental Database Management Software +61 2 8875 7948<br />
Contaminant Name: 1,3,5 Trimethylbenzene<br />
TDI oral<br />
Organisation<br />
Description Target organ/Critical Effect Reference Web link<br />
US EPA Provisional Peer Reviewed Toxicity<br />
Values (PPRTV)<br />
Office of Environmental <strong>Health</strong> Hazard<br />
<strong>Assessment</strong><br />
The database <strong>for</strong> 1,3,5-trimethylbenzene is<br />
inadequate to derive a provisional RfD<br />
Groups of 10 male and 10 female Sprague-<br />
Dawley rats were administered 1,3,5-TMB by<br />
gavage in corn oil.<br />
n/a n/a http://rais.ornl.gov/tox/unauthorized.shtml<br />
Abnormal clinical observations consisted of IITRI (1995). 90-Day oral gavage toxicity study of 1,3,5-trimethylbenzene in<br />
discoloured and/or wet inguinal fur and rats with a recovery group. Industry Institute of Toxicology Research Institute.<br />
salivation in the highest dose group of both Study conducted <strong>for</strong> Koch Industries Inc., Wichita, KS.<br />
sexes. Critical effects included increases in<br />
mean absolute liver weight and mean<br />
relative kidney weight.<br />
http://oehha.ca.gov/water/pals/124135tmb.html<br />
<strong>Risk</strong> <strong>Assessment</strong> In<strong>for</strong>mation System<br />
Texas Commission on Environmental<br />
Quality<br />
Not provided<br />
The value is provided by the US EPA National<br />
Centre <strong>for</strong> Environmental <strong>Assessment</strong> (NCEA)<br />
IITRI (1995). 90-Day oral gavage toxicity study of 1,3,5-trimethylbenzene in http://rais.ornl.gov/tox/rap_toxp.shtml<br />
rats with a recovery group. Industry Institute of Toxicology Research Institute.<br />
dec in body wt gain; clinical observations; Study conducted <strong>for</strong> Koch Industries Inc., Wichita, KS.<br />
inc liver/kidney wt in rats<br />
Not provided Not provided http://www.tceq.state.tx.us/remediation/rrr.html<br />
TDI inhal<br />
Organisation<br />
<strong>Health</strong> and Safety Executive (HSE)<br />
Description Response Reference Web link<br />
8 hour long term workplace exposure limit Not provided Not provided http://www.hse.gov.uk/<br />
US EPA Provisional Peer Reviewed Toxicity<br />
Values (PPRTV)<br />
Insufficient in<strong>for</strong>mation to derive a provisional<br />
RfD <strong>for</strong> 1,3,5-trimethylbenzene. Battig study<br />
deemed to be insufficient. No chronic inhalation<br />
toxicity studies located.<br />
n/a n/a http://rais.ornl.gov/tox/unauthorized.shtml<br />
<strong>Risk</strong> <strong>Assessment</strong> In<strong>for</strong>mation System<br />
Texas Commission on Environmental<br />
Quality<br />
Not provided<br />
The value is provided by the US EPA National<br />
Centre <strong>for</strong> Environmental <strong>Assessment</strong> (NCEA)<br />
CNS effects, asthma-like bromchitis, Battig et al 1958<br />
http://rais.ornl.gov/tox/rap_toxp.shtml<br />
aneima, blood clot effects<br />
Not provided Not provided http://www.tceq.state.tx.us/remediation/rrr.html<br />
ID oral<br />
Organisation<br />
Description Response Reference Web link<br />
US EPA Provisional Peer Reviewed Toxicity<br />
Values (PPRTV)<br />
There are no human or animal carcinogenicity<br />
data<br />
n/a n/a http://rais.ornl.gov/tox/unauthorized.shtml<br />
ID inhal<br />
Organisation<br />
Description Response Reference Web link<br />
(Page 2 of 2) (EIC pro<strong>for</strong>ma 1,3,5-trimethylbenzene.xls 28/08/2009)
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