Product Information Sheet - Lohmann Animal Health

Infectious Bursal Disease
From an economic point of view, Infectious Bursal Disease (IBD), also
known as Gumboro Disease, is one of the most important poultry diseases
worldwide. It is a highly contagious viral disease, affecting the immune
system of chickens. Young chickens up to 6 weeks of age are most
susceptible to the virus, depending on their level of maternal immunity
against the disease. The IBD virus targets and destroys the B cells in the
bursa of Fabricius which is a central organ for the immune response in
the young chicken. Infections by classic strains initially result in swelling
of the bursa, followed by atrophy. On the other hand, variant strains usually
cause bursal atrophy in the absence of inflammation.
The immune status of the flock to be vaccinated should be determined
prior to using this vaccine. Vaccination programs should address the
breed of bird, the parent vaccination program utilized and the history
of IBD in each operation/facility. Ask your representative of Lohmann
Animal Health Technical Support for more information.
Live IBDV vaccine rotation
Broiler producers customarily change the vaccination programs according
to seasonal variation in the level of field challenge. Live IBDV vaccines
are classified according to their virulence from mild to intermediate plus
or hot. Since each vaccine type is able to break through different levels of
maternal antibodies, it is essential to know when such levels will be low
enough to allow the vaccine virus to infect the bursa, replicate and generate
a protective immunity. Poultry flocks are usually formed by chickens
from different breeder flocks, exhibiting a great variation in the levels
of maternal antibodies at day of age. Under those circumstances, live
intermediate, non-cloned vaccines are an excellent choice due to their
broad antigenic diversity associated with the presence of different viral
subpopulations, their ability to break high and variable levels of maternal
antibodies, without causing immunosuppression and their capacity to
generate a primary immune response before the administration of inactivated
vaccines in breeders.
– Non-cloned
– High breakthrough titer
– Improved performance
Producers can make their choice from the range of live IBD vaccines from Lohmann Animal Health
(below). The products offered cover the whole spectrum of invasiveness, from mild strains to
intermediate plus.
Categorization of live IBD vaccines
– Microscopic lesions
of the Bursa
– Works in the face of
maternal antibodies
Mild Intermediate Intermediate Plus
– Serological response
– Bursa to body
weight ratio
– Immunosuppression
– Dose needed
to immunize
PF_MEN_CC010_LV:1478_010610
Prevention first.
AviPro® Vibursa CE – Live vaccine against Infectious Bursal Disease. For veterinary use only.
Check with your poultry pathologist before vaccinating chickens suspected of having been
recently exposed to Infectious Bursal Disease. Vaccination program: 1 dose at 10 days,
for chicks with no detectable maternal antibodies at day-of-age; 2 doses for chicks with
maternal antibodies: first at 10–14 days and second 2–3 weeks later. Prepare and administer
the vaccine according to package insert recommendations. Store vaccine between 2–7 ºC
(35-45 ºF). Withdrawal period: 21 days for the U.S. The vaccine is produced and controlled
according to USDA recommendations and specifications.
Lohmann Animal Health International
375 China Road
Winslow, Maine 04901, USA
Phone: (+1) 207-873 3989
www.lahinternational.com