Papel de las actividades superóxido dismutasa y catalasa en la ...

ABSTRACT
Photobacterium damselae subsp. piscicida is a gram negative bacterium, capable
to survive as intracellular pathogen within sole phagocytes, thanks to the protective
action of superoxide dismutase and catalase activities. These enzymes confer the
pathogen resistance against oxygen reactive radicals produced within phagocytes during
the respiratory burst. Therefore, both of these enzymes can be considered important
virulence factors for P. damselae subsp. piscicida, facilitating its invasion and disease
establishment. Research on disease prevention has been focused on the use of
microorganisms capable to stimulate the respiratory burst activity of sole phagocytes.
Assayed microorganisms include the microalga Porphyridium cruentum and two
potential probiotic bacteria strains. Results obtained are promising, since the microalga
and one strain of the assayed bacteria, Pdp11, are capable to stimulate the respiratory
burst activity and, therefore, confer resistance against the disease. A new research field
is opened in the fight against pseudotuberculosis, applying substances from algae or
bacterial cells that may be considered as probiotics.
67