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EUROINVENT 2013<br />

8.16.<br />

Title<br />

NEW ANTIBACTERIAL INHIBITORS<br />

Lozan-Tirsu Carolina, Gulea Aurelian, Tsapkov Victor,<br />

Authors<br />

Rudic Valeriu, Barba Nicanor, Corja Ion<br />

Institution Moldova State University<br />

Patent no. MD 4112, 4069, 4016<br />

Chemical synthesis, characterization of coordination<br />

compounds and their antibacterial evaluation as selective<br />

inhibitors of Gram-positive (Staphylococcus aureus and<br />

Bacillus cereus) and Gram-negative (Escherichia coli,<br />

Shigela sonnei and Salmonella abony) microorganisms<br />

Description EN have been carried out. New c<strong>op</strong>per tiosemicarbazidates<br />

displaying high antimicrobial activity have been<br />

obtained using the directed synthesis method. The new<br />

compounds have low toxicity. Additionally they display<br />

selective antibacterial activity in the concentration range<br />

0,009-18,7µg/mL.<br />

Class no. 4. Medicine - Health Care - Cosmetics<br />

8.17.<br />

NEW ORGANIC MOLECULE AS ANTICANCER<br />

Title<br />

DRUG<br />

Gulea Aurelian, Jalba Angela, Tsapkov Victor, Barba<br />

Authors<br />

Nicanor, Sofroni Larisa.<br />

Institution Moldova State University<br />

Patent no. MD 4126<br />

Obtaining of new anticancer agents by means of<br />

thiosemicarbazones fluororganic compounds. New<br />

fluororganic compounds displaying high cancerostatic<br />

activity by means of directed synthesis method have<br />

Description EN<br />

been obtained. The resulting drug possesses anticancer<br />

activity, which 1.5 times exceeds the activity of<br />

doxorubicine of prostate cancer LNCaP cell proliferation<br />

inhibitors<br />

Class no. 4. Medicine - Health Care - Cosmetics<br />

INTERNATIONAL EXHIBITS<br />

78

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