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EUROINVENT 2013
24.2
Title EN
Authors
Institution
Patent no.
Description
EN
Class no.
Biotechnological proceeding to get fungal biomass of
Lentinula edodes with immunomodulatory, antitumoral
and antiinfection properties
Marian Petre
University of Pitesti
RO121678/2008
The invention refers to the biotechnology of submerged cultivation
of Lentinula edodes mushroom species by using a natural nutritive
culture medium in order to get the fungal biomass having
immunomodulatory, antitumoral and antiinfection properties.
The fungal biomass with immunomodulatory, antitumor and
infectious properties is produced by in vitro cultivation of
mushroom species Lentinula edodes, in a liquid nutrient medium,
consisting of the following natural ingredients: rice bran at a rate of
10 ... 15% rye seed, shelled, germinated for 24 ... 48 h and then
ground very fine 15 ... 20%, soy peptone 5 ... 10%, yeast extract 1
... 5% deionized water the appropriate volume to achieve 100%
total percentage of the final solution based on the equivalent
volume-weight ratio.
The invention presents the following specific advantages:
- the significant reduction of the period of necessary time to acquire
the fungal biomass comparing to another cultivation methods that
are already known;
- the concentration increasing of the active biological compounds,
particularly of β-glucans by using a nutritive media of very specific
culture for this kind of eatable mushrooms which has
pharmaceutical remarkable qualities.
The mycelia biomass produced through this biotechnological
proceeding contains active biological compounds, such as exopolysaccharides,
respectively, β-glucans and, also glycol-proteins
and ergosterols. This biomass can be used for food supplements
producing having the property to modulate the human immunity of
organism and heal tumors and infections.
3. Agriculture and Food Industry
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