eur op eanexhibitionofcreati vityandinnovation - Europe Direct Iasi
eur op eanexhibitionofcreati vityandinnovation - Europe Direct Iasi
eur op eanexhibitionofcreati vityandinnovation - Europe Direct Iasi
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EUROINVENT 2013<br />
22.2.<br />
Title EN<br />
Authors<br />
Institution<br />
Description<br />
EN<br />
Class<br />
The Effects of Using A Dry Salt Inhaler Aerosols on<br />
Adults with Obstructive Respiratory Pathology<br />
Radu CRIȘAN-DABIJA, Traian MIHĂESCU<br />
University of Medicine and Pharmacy „Grigore T. P<strong>op</strong>a”<br />
Iași<br />
This study is a genuine breakthrough clinical research,<br />
unique in Romania, that scientifically proved for the first<br />
time, the benefits of halotherapy on patients with obstructive<br />
respiratory diseases.<br />
Introduction: The clinical benefits of salt air-ions are widely<br />
recognized but the mechanisms are scarcely studied and<br />
there is not enough available clinical data to prove the<br />
efficacy of adding halotherapy to regular treatment.<br />
Halotherapy is responsable for 5 therapeutical actions:<br />
mucolysis, antibacteriologic agent, anti-inflammatory agent,<br />
and immunomodulator - hyposensibilizing agent. We<br />
conducted a study where we use a dry-salt inhaler on patients<br />
with asthma and COPD with the purpose to prove the<br />
efficacy of adding halotherapy to regular bronchodilatatory<br />
medication.<br />
Methods:This study was double-blind, randomized trial,<br />
single crossed. During the 12 months of the study there were<br />
4 visits. The total patient p<strong>op</strong>ulation - 128 individuals (76 –<br />
asthma and 52 - COPD stages II and III) was divided in 2<br />
arms, crossed after first evaluation<br />
visit (V1).<br />
Results:The study revealed an improvement of all spirometry<br />
parameters after the first month of treatment with salt<br />
aerosols versus placebo. The final data showed an overall<br />
improvement of FVC by 4%, 14% improvement of the FEV1<br />
and 25% improvement of PEF parameter – showing<br />
significant improvement in asthma patients condition. Also,<br />
analyzing the quality of life responses we found out that the<br />
scores of the patients that used salt aerosols were improved<br />
throughout the study by 24% showing a significant impact<br />
on the quality of life.<br />
X. Innovative Researches<br />
NATIONAL<br />
170