eur op eanexhibitionofcreati vityandinnovation - Europe Direct Iasi

EUROINVENT 2013
22.2.
Title EN
Authors
Institution
Description
EN
Class
The Effects of Using A Dry Salt Inhaler Aerosols on
Adults with Obstructive Respiratory Pathology
Radu CRIȘAN-DABIJA, Traian MIHĂESCU
University of Medicine and Pharmacy „Grigore T. Popa”
Iași
This study is a genuine breakthrough clinical research,
unique in Romania, that scientifically proved for the first
time, the benefits of halotherapy on patients with obstructive
respiratory diseases.
Introduction: The clinical benefits of salt air-ions are widely
recognized but the mechanisms are scarcely studied and
there is not enough available clinical data to prove the
efficacy of adding halotherapy to regular treatment.
Halotherapy is responsable for 5 therapeutical actions:
mucolysis, antibacteriologic agent, anti-inflammatory agent,
and immunomodulator - hyposensibilizing agent. We
conducted a study where we use a dry-salt inhaler on patients
with asthma and COPD with the purpose to prove the
efficacy of adding halotherapy to regular bronchodilatatory
medication.
Methods:This study was double-blind, randomized trial,
single crossed. During the 12 months of the study there were
4 visits. The total patient population - 128 individuals (76 –
asthma and 52 - COPD stages II and III) was divided in 2
arms, crossed after first evaluation
visit (V1).
Results:The study revealed an improvement of all spirometry
parameters after the first month of treatment with salt
aerosols versus placebo. The final data showed an overall
improvement of FVC by 4%, 14% improvement of the FEV1
and 25% improvement of PEF parameter – showing
significant improvement in asthma patients condition. Also,
analyzing the quality of life responses we found out that the
scores of the patients that used salt aerosols were improved
throughout the study by 24% showing a significant impact
on the quality of life.
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