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EUROINVENT 2013
8.63.
Title
Authors
Institution
Patent no.
Description EN
Class no.
PSEUDOMYXOMA PERITONEI: OPTIMIZED
ALGORITHM OF THE DIAGNOSIS AND
TREATMENT
MIŞIN Igor, GHIDIRIM Gheorghe, MIŞINA Anna,
VOZIAN Marin, ZASTAVNIŢCHI Gheorghe
National Scientific-Practical Center of Emergency
Medicine (NCPCEM)
Certificat pending
Pseudomyxoma peritonei (PMP) is a rare, chronic, relapsing,
diagnostically challenging, and poorly understood disease
characterized by disseminated mucinous ascites and peritoneal
implants. PMP usually develops secondary to mucinous
neoplasms of the appendix and/or the ovary. The most
common sites of origin are considered the appendix and the
ovary, although other sites, such as the gallbladder, stomach,
pancreas, colon, uterus, fallopian tubes, urinary bladder, breast
and lung. In summary, PMP is a severe condition frequently
inducing complications which require emergency surgical
treatment such as intestinal obstruction or abdominal
compartment syndrome. We described the first PMP-induced
ACS successfully treated by surgical decompression.
Abdominal hypertension and compartment syndrome must be
considered in all the patients with PMP and if recognized
immediate abdominal decompression by surgical debulking,
peritoneal stripping combined with intraoperative hyperthermic
intraperitoneal chemotherapy should be considered. Our
experience highlights that PMP requires careful observation, as
it might be detected after a long-term follow-up period postappendectomy
for appendiceal mucocele. Histology is always
required and should be achieved by laparotomy. The
therapeutic recommendations are controversial due to the rarity
of PMP, the lack of randomized studies, and its complex
biology.
4. Medicine - Health Care - Cosmetics
Fig. 1 Abdominal CT-scan demonstrating mucinous ascites
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