njit-etd2003-081 - New Jersey Institute of Technology

njit-etd2003-081 - New Jersey Institute of Technology njit-etd2003-081 - New Jersey Institute of Technology

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25 and the target cell is the same as the pre- and post- ganglionic neurotransmitter, acetylcholine. Although acetylcholine generally has an excitatory effect, it is also known to have inhibitory effects as well, such as the slowing of the heart by the vagus nerve. In Figure 2.5, it is important to realize that some organs, such as the heart, eyes, and stomach, receive autonomic activity from both the sympathetic and parasympathetic nervous systems. This is often called "dual innervation". Usually, but not always, whatever affects the sympathetic nervous system has on the effector cells; the parasympathetic nervous system has the opposite effect [5]. In general, the sympathetic nervous system increases its response under conditions of stress. It is responsible for what is known as the fight-or-flight response. On the other hand, activity of the parasympathetic nervous system is associated with relaxing and the storing of energy. For example, heart rate increases with sympathetic activity and decreases with parasympathetic activity. Table 2.2 summarizes the effects of the autonomic nervous system on selected organs. Dual innervation by nerve fibers that cause opposite responses provides a very fine degree of control over the effector organ- it is like equipping a car with both an accelerator and a brake [5]. One can slow the car simply by decreasing the pressure on the accelerator; however, the combined effects of releasing the accelerator and applying the brake provide faster and more accurate control. Analogously, the sympathetic and parasympathetic divisions are usually activated reciprocally; that is, as the activity of one division is increased, the activity of the other is decreased. In addition to dual innervation, another important physiological characteristic is that the sympathetic and parasympathetic nervous systems are continually active.

26 Without these sympathetic and parasympathetic tones, each nervous system would only be able to produce one desired output, such as increasing heart rate. For instance, when sympathetic tone increases, heart rate increases. Conversely, when sympathetic tone decreases below its basal rate, the heart rate will decrease because of less sympathetic influence. Figure 2.5 The sympathetic nervous system and parasympathetic nervous system. (From E. N. Marieb, Human Anatomy and Physiology, 3 rd ed. New York: The Benjamin/Cummings Publishing Company, Inc., 1995.)

26<br />

Without these sympathetic and parasympathetic tones, each nervous system would only<br />

be able to produce one desired output, such as increasing heart rate. For instance, when<br />

sympathetic tone increases, heart rate increases. Conversely, when sympathetic tone<br />

decreases below its basal rate, the heart rate will decrease because <strong>of</strong> less sympathetic<br />

influence.<br />

Figure 2.5 The sympathetic nervous system and parasympathetic nervous system. (From<br />

E. N. Marieb, Human Anatomy and Physiology, 3 rd ed. <strong>New</strong> York: The<br />

Benjamin/Cummings Publishing Company, Inc., 1995.)

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