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njit-etd2003-081 - New Jersey Institute of Technology

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229<br />

Figure 5.61 presents a principal component plot <strong>of</strong> the data set containing 47<br />

COPD at rest and 8 normal subjects at 50%, 75% and 100% load. The data set gave the<br />

following principal components (PC):<br />

1 st PC: rsp — The respiration rate.<br />

2nd PC: HF _ coh_ HR_ BP — Coherence <strong>of</strong> HR and BP IIBI signals in the HF range<br />

(0.15 - 0.4 Hz).<br />

3 rd PC: HF_pcoh_HR_BP — Partial Coherence <strong>of</strong> HR and BP IIBI signals in the<br />

HF range (0.15 - 0.4 Hz).<br />

This indicated that the largest variance between COPD at rest and normal subjects<br />

during exercise was the breathing rate (respiration). The second largest variance was the<br />

interrelationships between HR and blood pressure in the HF range. The third largest<br />

variance was the partial interrelationships between HR and blood pressure in the HF<br />

range. The 1 st PC <strong>of</strong> the respiration indicated that the higher breathing rate <strong>of</strong> the COPD<br />

subjects was not the same in the HRV sense even though normal subjects increased their<br />

respiration rate to a similar level. Once the respiration PC was removed, the residual<br />

interrelationship was that between HR and blood pressure in the HF range.

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