njit-etd2003-081 - New Jersey Institute of Technology

njit-etd2003-081 - New Jersey Institute of Technology njit-etd2003-081 - New Jersey Institute of Technology

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145 again repeated over and over for the entire duration of data collection. Hence each COPD subject breathed at the random rate at which the subject was comfortable and still gave a flat power spectrum over the frequencies of interest. These boxes were used for convenience and simplicity without changing the objective of broadband respiration signal generation. 4.2.10 Principal Component Analysis The central idea of Principal component analysis (PCA) is to reduce the dimensionality of the data set while retaining as much as possible the variation in the data set. Principal components (PC's) are linear transformations of the original set of variables. PC's are uncorrelated and ordered so that the first few PC's contain most of the variations in the original data set [63]. The first PC has the geometric interpretation that it is a new set of the coordinate axes that maximizes the variation of the projections of the data points onto the new coordinate axes. In this dissertation a data set obtained from real data and analysis results (coherence, partial coherence) that contained 15 parameters is shown in Table 4.2. The first three parameters were the actual rate values taken from acquired data of normal and COPD subjects (i.e. heart rate in beats per minute, respiration in breaths per minute and blood pressure in beats per minute). The other parameters were obtained from LF and HF weighted values of the coherence/partial coherence cross-spectral analyses.

146 Table 4.2 Parameters That Make Up the Data Set Used for PCA and Cluster Analysis Parameter Respiration Heart Rate Blood Pressure LF Coherence HR-RESP LF Coherence HR-BP LF Coherence BP-RESP HF Coherence HR-RESP HF Coherence HR-BP HF Coherence BP-RESP LF Partial Coherence HR-RESP LF Partial Coherence HR-BP LF Partial Coherence BP-RESP HF Partial Coherence HR-RESP HF Partial Coherence HR-BP HF Partial Coherence BP-RESP Name RSP HR BP LF_coh_HR_rsp LF_coh HR_BP LF coh-BP rsp HF_coh_HR_rsp HF_coh_HR_BP HF_coh_BP_rsp LF_pcoh_HR_rsp LF_pcoh_HR_BP LF_pcoh_BP_rsp HF_pcoh_HR_rsp HF pcoh_HR_BP HF_pcoh_BP_rsp The data set was entered into the Matlab PCA program. The results are three principal components with associated eigenvalues of the covariances calculated from the data set. The range of the eigenvalues was normalized to -1, +1 and the parameter with the highest positive eigenvalues was the principal component of the data set. In the example shown in table 4.3, the three PC's of a fictitious data set were: 1. PC1 = BP with eigenvalue 0.3800 2. PC2 = HF_ coh _ BP_ rsp with eigenvalue 0.4961 3. PC3 = RSP with eigenvalue 0.3099

145<br />

again repeated over and over for the entire duration <strong>of</strong> data collection. Hence each<br />

COPD subject breathed at the random rate at which the subject was comfortable and still<br />

gave a flat power spectrum over the frequencies <strong>of</strong> interest.<br />

These boxes were used for convenience and simplicity without changing the<br />

objective <strong>of</strong> broadband respiration signal generation.<br />

4.2.10 Principal Component Analysis<br />

The central idea <strong>of</strong> Principal component analysis (PCA) is to reduce the dimensionality<br />

<strong>of</strong> the data set while retaining as much as possible the variation in the data set. Principal<br />

components (PC's) are linear transformations <strong>of</strong> the original set <strong>of</strong> variables. PC's are<br />

uncorrelated and ordered so that the first few PC's contain most <strong>of</strong> the variations in the<br />

original data set [63]. The first PC has the geometric interpretation that it is a new set <strong>of</strong><br />

the coordinate axes that maximizes the variation <strong>of</strong> the projections <strong>of</strong> the data points<br />

onto the new coordinate axes.<br />

In this dissertation a data set obtained from real data and analysis results<br />

(coherence, partial coherence) that contained 15 parameters is shown in Table 4.2. The<br />

first three parameters were the actual rate values taken from acquired data <strong>of</strong> normal and<br />

COPD subjects (i.e. heart rate in beats per minute, respiration in breaths per minute and<br />

blood pressure in beats per minute). The other parameters were obtained from LF and<br />

HF weighted values <strong>of</strong> the coherence/partial coherence cross-spectral analyses.

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