WHO monographs on selected medicinal plants - travolekar.ru

<strong>WHO</strong> <strong>monographs</strong> on selected medicinal plants
Alcohol-soluble extractive
Not less than 45% (1).
Loss on drying
To be established in accordance with national requirements.
Pesticide residues
The recommended maximum limit of aldrin and dieldrin is not more
than 0.05 mg/kg (13). For other pesticides see the European Pharmacopoeia
(13) and the <strong>WHO</strong> guidelines on assessing quality of herbal medicines
with reference to contaminants and residues (12) and pesticide
residues (14).
Heavy metals
For maximum limits and analysis of heavy metals, consult the <strong>WHO</strong>
guidelines on assessing quality of herbal medicines with reference to contaminants
and residues (12).
Radioactive residues
Where applicable, consult the <strong>WHO</strong> guidelines on assessing quality of
herbal medicines with reference to contaminants and residues (12).
Chemical assays
To be established in accordance with national requirements.
Major chemical constituents
Contains 5–9% essential oil with major constituents being -thujene (50–
61%), sabinene (5%), -pinene (8%) and -phellandrene (2%). Major
triterpene constituents of biological interest are members of the boswellic
acids (more than 12) including 11-oxo--boswellic acid, 3-O-acetyl-11-
oxo--boswellic acid, -boswellic acid, -boswellic acid, 3-O-acetyl-boswellic
acid, and 3-O-acetyl -boswellic acid (3, 15–17). The structures
of representative boswellic acids are presented below.
Medicinal uses
Uses supported by clinical data
Orally for the management of arthritis, bronchial asthma, Crohn’s disease
and ulcerative colitis (18–22).
Uses described in pharmacopoeias and well established documents
Orally for the treatment of rheumatism and arthritis (1, 2, 23).
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