WHO monographs on selected medicinal plants - travolekar.ru
WHO monographs on selected medicinal plants - travolekar.ru WHO monographs on selected medicinal plants - travolekar.ru
Cortex Viburni Prunifolii pore canals and rounded to irregular lumen, which frequently contain reddish to brownish content. Bast fibres absent. The medullary rays are mostly 1–2 cells wide, and contain either starch, tannin, orange-brownish amorphous masses or calcium oxalate crystals. Rosette aggregates of calcium oxalate found in the cells of the cortex, medullary rays and phloem are up to 54 μm in diameter. Monoclinic crystals also occur in these regions, but are fewer in number and only up to 25 μm in length. Starch grains present in these regions are simple and spheroidal to 2–3-compound, the individual grains being up to 23 μm in diameter (6). Powdered plant material Stem bark: light brown to moderate yellowish-brown. Cork layer in surface view. Stone cells numerous, rounded or elongated, in groups or isolated, with thick, porous, lignified walls and with reddish to brownish lumen and up to 260 μm in length; numerous fragments of lignified cork with brownish walls and polygonal in shape; calcium oxalate in rosette aggregates and monoclinic prisms up to 57 μm in diameter or length; fragments composed of parenchyma cells containing starch grains or calcium oxalate in rosette aggregates or monoclinic prisms, oil globules or orange to olive brown-coloured amorphous masses; starch grains simple or 2- to 3-compound, the individual grains spheroidal, ovate, elliptical, pyriform or plano-convex, up to 23 μm in diameter or length; a few fragments having wood fibres with lignified walls, some with lumen of irregular width and with bordered pores (3, 6). Root bark: to be established in accordance with national requirements. General identity tests Macroscopic and microscopic examinations (3, 6) and thin-layer chromatography (1, 3). Purity tests Microbiological Tests for specific microorganisms and microbial contamination limits are as described in the
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<str<strong>on</strong>g>WHO</str<strong>on</strong>g> <str<strong>on</strong>g>m<strong>on</strong>ographs</str<strong>on</strong>g> <strong>on</strong> <strong>selected</strong> <strong>medicinal</strong> <strong>plants</strong><br />
viewed in cross-secti<strong>on</strong>, the sec<strong>on</strong>dary cortex is characterized by large<br />
subspherical groups of yellow sclereids and radially oriented medullary<br />
rays which are 1–2 cells broad. The parenchyma cells of the sec<strong>on</strong>dary<br />
cortex c<strong>on</strong>tain calcium oxalate prisms (up to 20 μm in length) and oil<br />
droplets. When viewed in l<strong>on</strong>gitudinal secti<strong>on</strong>, the sclereid aggregates are<br />
unusually l<strong>on</strong>g. The calcium oxalate crystals are arranged in l<strong>on</strong>gitudinal<br />
rows. Starch granules are infrequent, but when present, they are subspherical<br />
(2–6 μm in diameter). Scattered through the cortex are groups of<br />
st<strong>on</strong>e cells and occasi<strong>on</strong>al isolated st<strong>on</strong>e cells. Rifts or spaces of natural<br />
origin also occur in this regi<strong>on</strong>. Pericycle c<strong>on</strong>sists of parenchyma similar<br />
to the cortex, embedded with a few pericyclic fibres. The latter, when<br />
observed in l<strong>on</strong>gitudinal secti<strong>on</strong>s, possess an irregular lumen and obtuse<br />
or rounded ends. Phloem is of variable width, c<strong>on</strong>sisting of sieve tissue,<br />
phloem parenchyma and phloem rays; the phloem parenchyma c<strong>on</strong>tains<br />
starch grains, rosette aggregates and m<strong>on</strong>oclinic prisms of calcium oxalate,<br />
tannin, amorphous orange, yellow or olive brown masses and oil.<br />
The phloem rays vary from straight to slightly curved or wavy and, while<br />
mostly 1 to 2 cells in width, may be up to 3 cells in width, as best determined<br />
from tangential-l<strong>on</strong>gitudinal secti<strong>on</strong>s through this regi<strong>on</strong> of the<br />
bark. Scattered through the phloem are numerous groups of st<strong>on</strong>e cells.<br />
The margins of these groups are irregularly rounded, crenate, toothed and<br />
indented. Some of the phloem rays are intercepted in their outward course<br />
by groups of st<strong>on</strong>e cells. As the stems grow older, sec<strong>on</strong>dary cork cambia<br />
originate successively in the cortex, pericycle and outer phloem forming<br />
wavy borke areas in these z<strong>on</strong>es which c<strong>on</strong>tain groups of st<strong>on</strong>e cells and,<br />
in the case of the pericyclic regi<strong>on</strong>, pericyclic fibres. In old stem bark, the<br />
medullary rays (phloem rays) reach outward to the periderm (3, 6).<br />
Root bark: cork of variable thickness, composed of somewhat lignified<br />
cork cells which are tangentially el<strong>on</strong>gated in cross-secti<strong>on</strong>s and polyg<strong>on</strong>al<br />
in surface secti<strong>on</strong>s, many of which possess orange or yellowish-orange or<br />
brownish c<strong>on</strong>tents. Phellogen of tangentially el<strong>on</strong>gated meristematic cells.<br />
A sec<strong>on</strong>dary cortex of a narrow z<strong>on</strong>e of tangentially el<strong>on</strong>gated parenchyma<br />
cells, some of which c<strong>on</strong>tain orange or brownish amorphous masses,<br />
tannin, oil globules, starch, m<strong>on</strong>oclinic prisms and rosette aggregates of<br />
calcium oxalate. Groups of st<strong>on</strong>e cells with irregularly indented margins<br />
and isolated st<strong>on</strong>e cells scattered through the regi<strong>on</strong>. Phloem c<strong>on</strong>sists of a<br />
relatively broad z<strong>on</strong>e comprising a matrix of parenchyma and sieve tubes<br />
separated into a number of obl<strong>on</strong>g or curved phloem patches by medullary<br />
rays which, in cross-secti<strong>on</strong>s, <strong>ru</strong>n nearly straight or curve and c<strong>on</strong>verge<br />
in groups. The st<strong>on</strong>e cell groups are numerous and frequently deeply<br />
notched, the individual st<strong>on</strong>e cells are str<strong>on</strong>gly lignified with prominent<br />
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